ID   C9IY79_HUMAN            Unreviewed;       141 AA.
AC   C9IY79;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 8.
DT   27-MAR-2024, entry version 90.
DE   SubName: Full=Phospholipase D1 {ECO:0000313|Ensembl:ENSP00000400639.1};
DE   Flags: Fragment;
GN   Name=PLD1 {ECO:0000313|Ensembl:ENSP00000400639.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000400639.1, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000400639.1, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J.,
RA   Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P.,
RA   Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A.,
RA   Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L.,
RA   Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G.,
RA   Sodergren E., Song X.Z., Steffen D., Wei S., Wheeler D.A., Wright M.W.,
RA   Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M.,
RA   Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P.,
RA   Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H.,
RA   Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J.,
RA   Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W.,
RA   Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B.,
RA   Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O.,
RA   Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J., Zhang X.,
RA   Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R.,
RA   Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0007829|PubMed:18669648}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=18669648; DOI=10.1073/pnas.0805139105;
RA   Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,
RA   Elledge S.J., Gygi S.P.;
RT   "A quantitative atlas of mitotic phosphorylation.";
RL   Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
RN   [3] {ECO:0000313|Ensembl:ENSP00000400639.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AC008134; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC078953; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; C9IY79; -.
DR   SMR; C9IY79; -.
DR   MassIVE; C9IY79; -.
DR   PeptideAtlas; C9IY79; -.
DR   ProteomicsDB; 7629; -.
DR   Antibodypedia; 3866; 333 antibodies from 40 providers.
DR   Ensembl; ENST00000418087.1; ENSP00000400639.1; ENSG00000075651.17.
DR   UCSC; uc062pys.1; human.
DR   HGNC; HGNC:9067; PLD1.
DR   VEuPathDB; HostDB:ENSG00000075651; -.
DR   GeneTree; ENSGT00940000155015; -.
DR   HOGENOM; CLU_1986653_0_0_1; -.
DR   OMA; EWRLDQI; -.
DR   ChiTaRS; PLD1; human.
DR   Proteomes; UP000005640; Chromosome 3.
DR   Bgee; ENSG00000075651; Expressed in gall bladder and 178 other cell types or tissues.
DR   ExpressionAtlas; C9IY79; baseline and differential.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR   InterPro; IPR001683; PX_dom.
DR   InterPro; IPR036871; PX_dom_sf.
DR   Pfam; PF00787; PX; 1.
DR   SUPFAM; SSF64268; PX domain; 1.
DR   PROSITE; PS50195; PX; 1.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|EPD:C9IY79,
KW   ECO:0007829|MaxQB:C9IY79};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT   DOMAIN          81..141
FT                   /note="PX"
FT                   /evidence="ECO:0000259|PROSITE:PS50195"
FT   NON_TER         141
FT                   /evidence="ECO:0000313|Ensembl:ENSP00000400639.1"
SQ   SEQUENCE   141 AA;  16525 MW;  7C9D5EEF3BEFE369 CRC64;
     MSLKNEPRVN TSALQKIAAD MSNIIENLDT RELHFEGEEV DYDVSPSDPK IQEVYIPFSA
     IYNTQGFKEP NIQTYLSGCP IKAQVLEVER FTSTTRVPSI NLYTIELTHG EFKWQVKRKF
     KHFQEFHREL LKYKAFIRIP I
//