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C9E895

- C9E895_RAT

UniProt

C9E895 - C9E895_RAT

Protein
Submitted name:

Glutamic acid decarboxylase 1, isoform CRA_a

Gene

Gad1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (03 Nov 2009)
      Previous versions | rss
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    Functioni

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. carboxy-lyase activity Source: InterPro
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. carboxylic acid metabolic process Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Glutamic acid decarboxylase 1, isoform CRA_aImported
    Submitted name:
    Glutamic acid decarboxylase 67 variant GAD67CImported
    Gene namesi
    Name:Gad1Imported
    ORF Names:rCG_26162Imported
    OrganismiRattus norvegicus (Rat)
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    Organism-specific databases

    RGDi2652. Gad1.

    Subcellular locationi

    GO - Cellular componenti

    1. axon terminus Source: Ensembl
    2. cell cortex Source: Ensembl
    3. mitochondrion Source: Ensembl
    4. presynaptic active zone Source: Ensembl

    Interactioni

    Protein-protein interaction databases

    STRINGi10116.ENSRNOP00000000008.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    KOiK01580.
    OMAiEYLYTKI.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProiIPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    IPR021115. Pyridoxal-P_BS.
    [Graphical view]
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.
    PROSITEiPS00392. DDC_GAD_HDC_YDC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C9E895-1 [UniParc]FASTAAdd to Basket

    « Hide

    MASSTPSPAT SSNAGADPNT TNLRPTTYDT WCGVAHGCTR KLGLKICGFL    50
    QRTNSLEEKS RLVSAFRERQ ASKNLLSCEN SDPGARFRRT ETDFSNLFAQ 100
    DLLPAKNGEE QTVQFLLEVV DILLNYVRKT FDRSTKVLDF HHPHQLLEGM 150
    EGFNLELSDH PESLEQILVD CRDTLKYGVR TGHPRFFNQL STGLDIIGLA 200
    GEWLTSTANT NMFTYEIAPV FVLMEQITLK KMREIIGWSN KDGDGIFSPG 250
    GAISNMYSIM AARYKYFPEV KTKGMAAVPK LVLFTSEHSH YSIKKAGAAL 300
    GFGTDNVILI KCNERGKIIP ADLEAKILDA KQKGFVPLYV NATAGTTVYG 350
    AFDPIQEIAD ICEKYNLWLH VDAAWGGGLL MSRKHRHKLS GIERANSVTW 400
    NPHKMMGVLL QCSAILVKEK GILQGCNQMC AGYLFQPDKQ YDVSYDTGDK 450
    AIQCGRHVDI FKFWLMWKAK GTVGFENQIN KCLELAEYLY AKIKNREEFE 500
    MVFNGEPEHT NVCFWYIPQS LRGVPDSPER REKLHRVAPK IKALMMESGT 550
    TMVGYQPQGD KANFFRMVIS NPAATQSDID FLIEEIERLG QDL 593
    Length:593
    Mass (Da):66,640
    Last modified:November 3, 2009 - v1
    Checksum:iEF83239C30301F69
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GQ468528 mRNA. Translation: ACV92036.1.
    CH473949 Genomic DNA. Translation: EDL79083.1.
    CH473949 Genomic DNA. Translation: EDL79084.1.
    RefSeqiNP_058703.1. NM_017007.1.
    UniGeneiRn.91245.

    Genome annotation databases

    GeneIDi24379.
    KEGGirno:24379.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GQ468528 mRNA. Translation: ACV92036.1 .
    CH473949 Genomic DNA. Translation: EDL79083.1 .
    CH473949 Genomic DNA. Translation: EDL79084.1 .
    RefSeqi NP_058703.1. NM_017007.1.
    UniGenei Rn.91245.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10116.ENSRNOP00000000008.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 24379.
    KEGGi rno:24379.

    Organism-specific databases

    CTDi 2571.
    RGDi 2652. Gad1.

    Phylogenomic databases

    KOi K01580.
    OMAi EYLYTKI.

    Miscellaneous databases

    NextBioi 603137.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProi IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    IPR021115. Pyridoxal-P_BS.
    [Graphical view ]
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    PROSITEi PS00392. DDC_GAD_HDC_YDC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    2. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    3. "Dynamic regulation of glutamate decarboxylase 67 gene expression by alternative promoters and splicing during rat testis maturation."
      Liu H., Zhang Y., Li S.
      Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Sprague-DawleyImported.

    Entry informationi

    Entry nameiC9E895_RAT
    AccessioniPrimary (citable) accession number: C9E895
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 3, 2009
    Last sequence update: November 3, 2009
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)