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Protein
Submitted name:

Glutamic acid decarboxylase 1, isoform CRA_a

Gene

Gad1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotation
LigandPyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Glutamic acid decarboxylase 1, isoform CRA_aImported
Submitted name:
Glutamic acid decarboxylase 67 variant GAD67CImported
Gene namesi
Name:Gad1Imported
ORF Names:rCG_26162Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi2652 Gad1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei404N6-(pyridoxal phosphate)lysineUniRule annotation1

Expressioni

Gene expression databases

BgeeiENSRNOG00000000007

Structurei

3D structure databases

SMRiC9E895
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0629 Eukaryota
COG0076 LUCA
KOiK01580
OMAiFHKHFFQ
OrthoDBiEOG091G07ZU

Family and domain databases

Gene3Di3.40.640.10, 1 hit
InterProiView protein in InterPro
IPR002129 PyrdxlP-dep_de-COase
IPR015424 PyrdxlP-dep_Trfase
IPR015421 PyrdxlP-dep_Trfase_major
IPR021115 Pyridoxal-P_BS
PfamiView protein in Pfam
PF00282 Pyridoxal_deC, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
PROSITEiView protein in PROSITE
PS00392 DDC_GAD_HDC_YDC, 1 hit

Sequencei

Sequence statusi: Complete.

C9E895-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASSTPSPAT SSNAGADPNT TNLRPTTYDT WCGVAHGCTR KLGLKICGFL
60 70 80 90 100
QRTNSLEEKS RLVSAFRERQ ASKNLLSCEN SDPGARFRRT ETDFSNLFAQ
110 120 130 140 150
DLLPAKNGEE QTVQFLLEVV DILLNYVRKT FDRSTKVLDF HHPHQLLEGM
160 170 180 190 200
EGFNLELSDH PESLEQILVD CRDTLKYGVR TGHPRFFNQL STGLDIIGLA
210 220 230 240 250
GEWLTSTANT NMFTYEIAPV FVLMEQITLK KMREIIGWSN KDGDGIFSPG
260 270 280 290 300
GAISNMYSIM AARYKYFPEV KTKGMAAVPK LVLFTSEHSH YSIKKAGAAL
310 320 330 340 350
GFGTDNVILI KCNERGKIIP ADLEAKILDA KQKGFVPLYV NATAGTTVYG
360 370 380 390 400
AFDPIQEIAD ICEKYNLWLH VDAAWGGGLL MSRKHRHKLS GIERANSVTW
410 420 430 440 450
NPHKMMGVLL QCSAILVKEK GILQGCNQMC AGYLFQPDKQ YDVSYDTGDK
460 470 480 490 500
AIQCGRHVDI FKFWLMWKAK GTVGFENQIN KCLELAEYLY AKIKNREEFE
510 520 530 540 550
MVFNGEPEHT NVCFWYIPQS LRGVPDSPER REKLHRVAPK IKALMMESGT
560 570 580 590
TMVGYQPQGD KANFFRMVIS NPAATQSDID FLIEEIERLG QDL
Length:593
Mass (Da):66,640
Last modified:November 3, 2009 - v1
Checksum:iEF83239C30301F69
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GQ468528 mRNA Translation: ACV92036.1
CH473949 Genomic DNA Translation: EDL79083.1
CH473949 Genomic DNA Translation: EDL79084.1
RefSeqiNP_058703.1, NM_017007.1
XP_017446943.1, XM_017591454.1
XP_017446944.1, XM_017591455.1
UniGeneiRn.91245

Genome annotation databases

GeneIDi24379
KEGGirno:24379

Similar proteinsi

Entry informationi

Entry nameiC9E895_RAT
AccessioniPrimary (citable) accession number: C9E895
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: April 25, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health