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C8XKS6

- C8XKS6_NAKMY

UniProt

C8XKS6 - C8XKS6_NAKMY

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Protein
Phosphoenolpyruvate carboxylase
Gene
ppc, Namu_4447
Organism
Nakamurella multipartita (strain ATCC 700099 / DSM 44233 / JCM 9543 / Y-104) (Microsphaera multipartita)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei163 – 1631 By similarityUniRule annotation
Active sitei605 – 6051 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Enzyme and pathway databases

BioCyciNMUL479431:GHQL-4482-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Namu_4447Imported
OrganismiNakamurella multipartita (strain ATCC 700099 / DSM 44233 / JCM 9543 / Y-104) (Microsphaera multipartita)Imported
Taxonomic identifieri479431 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesFrankineaeNakamurellaceaeNakamurella
ProteomesiUP000002218: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi479431.Namu_4447.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiHERTIAM.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C8XKS6-1 [UniParc]FASTAAdd to Basket

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MTQISDTLGQ SAALADVPPT SPGVDRDAAL RADVRRVGSL LGQTLVRQQG    50
PELLDLVEQV RGLTKQSREA AAATERQSAT LKVREMLAAL PIAVATELVR 100
AFATYFQLAN GAEQVHQVRE LRARETGDDH LAAVVQEIVT TLGTDALREA 150
VEALEVQPVF TAHPTEASRR SVLLKLQALA DILVVPTPAG SAARTRQDRK 200
LAEVIDLLWQ TDEIRQFRPT PVDEARNALF YLEAIVGDTI PALTDDLAAA 250
MAQHGVELSP EATPLLLGSW IGGDRDGNPN VTAAVTREVL ALQHQSAIAI 300
AIGKIDELLL ALSSSTVIAG ASDELVASIR TDLDHLPLLD PRVKELNKDE 350
PIRLKLTCVK AKLINTRARV NAGRAHEPGR DYASKGELLA DLAIVHRSLE 400
QHGGALAAAG ILATAQRALA VSGLNVAYMD IREHSEAHHQ VIAQLVDRLG 450
ELDRPYDSMS RPQRMRWLSK ELTSHRPLTT LPAPLDAAGT KTFSVFSEIK 500
DAQATYGPEV IVTYITSMTM GADDILAAAV LAREAGLIDV YGTPGDPTRG 550
PFAAIGFAPL LETVEELRKS AEVVDELLSD PTYREIVRLR GDVQEIMLGY 600
SDSNKQSGIT TSQWEIHKTE RLLRDLAARH GVSLTLFHGR GGTVGRGGGP 650
TYDSILAQPY GVITGAIKFT EQGEVISGKY GMPDLAKENL ALTVAATLRA 700
TTLHTESRQT AQELRDWDQW MEQVSDAAFA AYVGLIDDPD LPAYFLASTP 750
TEQLGQLNIG SRPARRPDSG GGIGGLRAIP WVFGWTQSRQ IVPGWFGVGS 800
GLRAAREAGG EQMLRTMHRK WHFFRTFISN VEMTLAKTDM GIAAMYVESL 850
VPAPLRRLFE VIKAEHDLTV AEVLRVTGEA ELLDDQPALK RTLGVREPYL 900
APISYLQVDL LNRIRSQADE QVDPQLRRAM LLTINGVAAG MRNTG 945
Length:945
Mass (Da):102,590
Last modified:November 3, 2009 - v1
Checksum:i1B81875B839768F0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001737 Genomic DNA. Translation: ACV80733.1.
RefSeqiYP_003203722.1. NC_013235.1.

Genome annotation databases

EnsemblBacteriaiACV80733; ACV80733; Namu_4447.
GeneIDi8450074.
KEGGinml:Namu_4447.
PATRICi22666596. VBINakMul62011_4510.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001737 Genomic DNA. Translation: ACV80733.1 .
RefSeqi YP_003203722.1. NC_013235.1.

3D structure databases

ModBasei Search...

Protein-protein interaction databases

STRINGi 479431.Namu_4447.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACV80733 ; ACV80733 ; Namu_4447 .
GeneIDi 8450074.
KEGGi nml:Namu_4447.
PATRICi 22666596. VBINakMul62011_4510.

Phylogenomic databases

eggNOGi COG2352.
HOGENOMi HOG000238647.
KOi K01595.
OMAi HERTIAM.
OrthoDBi EOG6TJ7T8.

Enzyme and pathway databases

BioCyci NMUL479431:GHQL-4482-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700099 / DSM 44233 / JCM 9543 / Y-104.

Entry informationi

Entry nameiC8XKS6_NAKMY
AccessioniPrimary (citable) accession number: C8XKS6
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: June 11, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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