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C8WXQ5

- C8WXQ5_ALIAD

UniProt

C8WXQ5 - C8WXQ5_ALIAD

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Protein
UvrABC system protein C
Gene
uvrC, Aaci_1864
Organism
Alicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / 104-1A) (Bacillus acidocaldarius)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision By similarity.UniRule annotationSAAS annotations

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-HAMAP
  2. excinuclease ABC activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. SOS response Source: UniProtKB-HAMAP
  2. nucleotide-excision repair Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Excision nucleaseUniRule annotationSAAS annotations

Keywords - Biological processi

DNA damage, DNA excisionUniRule annotationSAAS annotations, DNA repair, SOS responseUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciAACI521098:GCIO-1923-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit C
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:Aaci_1864Imported
OrganismiAlicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / 104-1A) (Bacillus acidocaldarius)Imported
Taxonomic identifieri521098 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesAlicyclobacillaceaeAlicyclobacillus
ProteomesiUP000001917: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. excinuclease repair complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex By similarity.UniRule annotationSAAS annotations

Protein-protein interaction databases

STRINGi521098.Aaci_1864.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini14 – 9178GIY-YIG By similarityUniRule annotation
Add
BLAST
Domaini196 – 23136UVR By similarityUniRule annotation
Add
BLAST

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation
Contains 1 GIY-YIG domain.UniRule annotation
Contains 1 UVR domain.UniRule annotation
Contains GIY-YIG domain.SAAS annotations
Contains UVR domain.SAAS annotations

Phylogenomic databases

eggNOGiCOG0322.
HOGENOMiHOG000279960.
KOiK03703.
OMAiQTIASCV.
OrthoDBiEOG6K13R9.

Family and domain databases

Gene3Di3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPiMF_00203. UvrC.
InterProiIPR027299. GIY-YIG_dom.
IPR000305. GIY-YIG_SF.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
[Graphical view]
PfamiPF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
[Graphical view]
SMARTiSM00465. GIYc. 1 hit.
SM00278. HhH1. 1 hit.
[Graphical view]
SUPFAMiSSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsiTIGR00194. uvrC. 1 hit.
PROSITEiPS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C8WXQ5-1 [UniParc]FASTAAdd to Basket

« Hide

MNQVIRDKLD LLPQRPGVYL MKGEGGEILY VGKAKVLRNR VRSYFTGTHD    50
TKTQVLVSQI RDFEYIVTDT VAEALLLECN LIKQHQPPYN IMLRDDKSYP 100
YIKLTKERHP RLQIVRQVKR DGAKYFGPYP NATSAQATKR LLDRLYPLRK 150
CKTLKKQVCL YYHIHQCLAP CVYDVDEATY EAMAKEISHF LNGGHQDVVR 200
ELEQKMQAAA ESLEFERAAE LRDLIRHIEQ VMQEQKVTWT DGIDRDVFGF 250
AEDRGLLSVQ VFFVRNGKLI ERQVQIAPHF DDPLTDFMSF VEQFYHERVD 300
LPKEILLPEG VPSEALAMVV DAKVLQPKRG PKRDLVDLAC ENARQALAEK 350
IQLIDRNLDR TLGAVMELGQ VLAIQPPRRI EAFDNSNFQG VDAVSAMVVF 400
IDGKPAKSEY RKYKIRSTQG PDDYEAIREV VRRRYSRLVR EQKPLPDLVV 450
IDGGKGQLRA ALSVLEGELG LEIPVCGLAK DERHRTSQLF FMDEEEPVRI 500
ERHSPAFYLL ERIQDEVHRF AVEFHRLRRS KTGFQSILDE IPGVGPERKK 550
AILRRFGSLK AVAAAQPEDF RGLGIGDKLA REIVARVREE LAARKQADGE 600
MEISSEAPFS 610
Length:610
Mass (Da):69,889
Last modified:November 3, 2009 - v1
Checksum:i6798D19B5FAF965B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001727 Genomic DNA. Translation: ACV58876.1.
RefSeqiYP_003185265.1. NC_013205.1.

Genome annotation databases

EnsemblBacteriaiACV58876; ACV58876; Aaci_1864.
GeneIDi8425381.
KEGGiaac:Aaci_1864.
PATRICi20847162. VBIAliAci73240_1814.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001727 Genomic DNA. Translation: ACV58876.1 .
RefSeqi YP_003185265.1. NC_013205.1.

3D structure databases

ModBasei Search...

Protein-protein interaction databases

STRINGi 521098.Aaci_1864.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACV58876 ; ACV58876 ; Aaci_1864 .
GeneIDi 8425381.
KEGGi aac:Aaci_1864.
PATRICi 20847162. VBIAliAci73240_1814.

Phylogenomic databases

eggNOGi COG0322.
HOGENOMi HOG000279960.
KOi K03703.
OMAi QTIASCV.
OrthoDBi EOG6K13R9.

Enzyme and pathway databases

BioCyci AACI521098:GCIO-1923-MONOMER.

Family and domain databases

Gene3Di 3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPi MF_00203. UvrC.
InterProi IPR027299. GIY-YIG_dom.
IPR000305. GIY-YIG_SF.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
[Graphical view ]
Pfami PF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
[Graphical view ]
SMARTi SM00465. GIYc. 1 hit.
SM00278. HhH1. 1 hit.
[Graphical view ]
SUPFAMi SSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsi TIGR00194. uvrC. 1 hit.
PROSITEi PS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27009 / DSM 446 / 104-1A.

Entry informationi

Entry nameiC8WXQ5_ALIAD
AccessioniPrimary (citable) accession number: C8WXQ5
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: May 14, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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