Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

UvrABC system protein C

Gene

uvrC

Organism
Alicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / JCM 5260 / NBRC 15652 / NCIMB 11725 / NRRL B-14509 / 104-1A) (Bacillus acidocaldarius)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExcision nucleaseUniRule annotationSAAS annotation
Biological processDNA damage, DNA excisionUniRule annotationSAAS annotation, DNA repair, SOS responseUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciAACI521098:G1GFZ-1892-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotationSAAS annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:Aaci_1864Imported
OrganismiAlicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / JCM 5260 / NBRC 15652 / NCIMB 11725 / NRRL B-14509 / 104-1A) (Bacillus acidocaldarius)Imported
Taxonomic identifieri521098 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesAlicyclobacillaceaeAlicyclobacillus
Proteomesi
  • UP000001917 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi521098.Aaci_1864

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 91GIY-YIGInterPro annotationAdd BLAST78
Domaini196 – 231UVRInterPro annotationAdd BLAST36
Domaini247 – 465UVRCInterPro annotationAdd BLAST219

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili199 – 219Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105CII Bacteria
COG0322 LUCA
HOGENOMiHOG000279960
KOiK03703
OMAiLFPIRQC
OrthoDBiPOG091H01BS

Family and domain databases

Gene3Di3.30.420.340, 1 hit
3.40.1440.10, 1 hit
HAMAPiMF_00203 UvrC, 1 hit
InterProiView protein in InterPro
IPR000305 GIY-YIG_endonuc
IPR035901 GIY-YIG_endonuc_sf
IPR010994 RuvA_2-like
IPR001943 UVR_dom
IPR036876 UVR_dom_sf
IPR004791 UvrC
IPR001162 UvrC_homol_region
IPR038476 UvrC_homol_region_sf
PfamiView protein in Pfam
PF01541 GIY-YIG, 1 hit
PF02151 UVR, 1 hit
PF08459 UvrC_HhH_N, 1 hit
SMARTiView protein in SMART
SM00465 GIYc, 1 hit
SUPFAMiSSF46600 SSF46600, 1 hit
SSF47781 SSF47781, 1 hit
SSF82771 SSF82771, 1 hit
TIGRFAMsiTIGR00194 uvrC, 1 hit
PROSITEiView protein in PROSITE
PS50164 GIY_YIG, 1 hit
PS50151 UVR, 1 hit
PS50165 UVRC, 1 hit

Sequencei

Sequence statusi: Complete.

C8WXQ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQVIRDKLD LLPQRPGVYL MKGEGGEILY VGKAKVLRNR VRSYFTGTHD
60 70 80 90 100
TKTQVLVSQI RDFEYIVTDT VAEALLLECN LIKQHQPPYN IMLRDDKSYP
110 120 130 140 150
YIKLTKERHP RLQIVRQVKR DGAKYFGPYP NATSAQATKR LLDRLYPLRK
160 170 180 190 200
CKTLKKQVCL YYHIHQCLAP CVYDVDEATY EAMAKEISHF LNGGHQDVVR
210 220 230 240 250
ELEQKMQAAA ESLEFERAAE LRDLIRHIEQ VMQEQKVTWT DGIDRDVFGF
260 270 280 290 300
AEDRGLLSVQ VFFVRNGKLI ERQVQIAPHF DDPLTDFMSF VEQFYHERVD
310 320 330 340 350
LPKEILLPEG VPSEALAMVV DAKVLQPKRG PKRDLVDLAC ENARQALAEK
360 370 380 390 400
IQLIDRNLDR TLGAVMELGQ VLAIQPPRRI EAFDNSNFQG VDAVSAMVVF
410 420 430 440 450
IDGKPAKSEY RKYKIRSTQG PDDYEAIREV VRRRYSRLVR EQKPLPDLVV
460 470 480 490 500
IDGGKGQLRA ALSVLEGELG LEIPVCGLAK DERHRTSQLF FMDEEEPVRI
510 520 530 540 550
ERHSPAFYLL ERIQDEVHRF AVEFHRLRRS KTGFQSILDE IPGVGPERKK
560 570 580 590 600
AILRRFGSLK AVAAAQPEDF RGLGIGDKLA REIVARVREE LAARKQADGE
610
MEISSEAPFS
Length:610
Mass (Da):69,889
Last modified:November 3, 2009 - v1
Checksum:i6798D19B5FAF965B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001727 Genomic DNA Translation: ACV58876.1
RefSeqiWP_012811162.1, NC_013205.1

Genome annotation databases

EnsemblBacteriaiACV58876; ACV58876; Aaci_1864
KEGGiaac:Aaci_1864

Similar proteinsi

Entry informationi

Entry nameiC8WXQ5_ALIAD
AccessioniPrimary (citable) accession number: C8WXQ5
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: March 28, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health