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C8WXQ5

- C8WXQ5_ALIAD

UniProt

C8WXQ5 - C8WXQ5_ALIAD

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Protein

UvrABC system protein C

Gene

uvrC

Organism
Alicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / 104-1A) (Bacillus acidocaldarius)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotationSAAS annotation

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-HAMAP
  2. excinuclease ABC activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. nucleotide-excision repair Source: UniProtKB-HAMAP
  2. SOS response Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Excision nucleaseUniRule annotationSAAS annotation

Keywords - Biological processi

DNA damage, DNA excisionUniRule annotationSAAS annotation, DNA repair, SOS responseUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciAACI521098:GCIO-1923-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:Aaci_1864Imported
OrganismiAlicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / 104-1A) (Bacillus acidocaldarius)Imported
Taxonomic identifieri521098 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesAlicyclobacillaceaeAlicyclobacillus
ProteomesiUP000001917: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. excinuclease repair complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi521098.Aaci_1864.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini14 – 9178GIY-YIGUniRule annotationAdd
BLAST
Domaini196 – 23136UVRUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation
Contains 1 GIY-YIG domain.UniRule annotation
Contains 1 UVR domain.UniRule annotation
Contains GIY-YIG domain.SAAS annotation
Contains UVR domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG0322.
HOGENOMiHOG000279960.
KOiK03703.
OMAiQTIASCV.
OrthoDBiEOG6K13R9.

Family and domain databases

Gene3Di3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPiMF_00203. UvrC.
InterProiIPR027299. GIY-YIG_dom.
IPR000305. GIY-YIG_SF.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
[Graphical view]
PfamiPF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
[Graphical view]
SMARTiSM00465. GIYc. 1 hit.
SM00278. HhH1. 1 hit.
[Graphical view]
SUPFAMiSSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsiTIGR00194. uvrC. 1 hit.
PROSITEiPS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C8WXQ5 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNQVIRDKLD LLPQRPGVYL MKGEGGEILY VGKAKVLRNR VRSYFTGTHD
60 70 80 90 100
TKTQVLVSQI RDFEYIVTDT VAEALLLECN LIKQHQPPYN IMLRDDKSYP
110 120 130 140 150
YIKLTKERHP RLQIVRQVKR DGAKYFGPYP NATSAQATKR LLDRLYPLRK
160 170 180 190 200
CKTLKKQVCL YYHIHQCLAP CVYDVDEATY EAMAKEISHF LNGGHQDVVR
210 220 230 240 250
ELEQKMQAAA ESLEFERAAE LRDLIRHIEQ VMQEQKVTWT DGIDRDVFGF
260 270 280 290 300
AEDRGLLSVQ VFFVRNGKLI ERQVQIAPHF DDPLTDFMSF VEQFYHERVD
310 320 330 340 350
LPKEILLPEG VPSEALAMVV DAKVLQPKRG PKRDLVDLAC ENARQALAEK
360 370 380 390 400
IQLIDRNLDR TLGAVMELGQ VLAIQPPRRI EAFDNSNFQG VDAVSAMVVF
410 420 430 440 450
IDGKPAKSEY RKYKIRSTQG PDDYEAIREV VRRRYSRLVR EQKPLPDLVV
460 470 480 490 500
IDGGKGQLRA ALSVLEGELG LEIPVCGLAK DERHRTSQLF FMDEEEPVRI
510 520 530 540 550
ERHSPAFYLL ERIQDEVHRF AVEFHRLRRS KTGFQSILDE IPGVGPERKK
560 570 580 590 600
AILRRFGSLK AVAAAQPEDF RGLGIGDKLA REIVARVREE LAARKQADGE
610
MEISSEAPFS
Length:610
Mass (Da):69,889
Last modified:November 3, 2009 - v1
Checksum:i6798D19B5FAF965B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001727 Genomic DNA. Translation: ACV58876.1.
RefSeqiWP_012811162.1. NC_013205.1.
YP_003185265.1. NC_013205.1.

Genome annotation databases

EnsemblBacteriaiACV58876; ACV58876; Aaci_1864.
GeneIDi8425381.
KEGGiaac:Aaci_1864.
PATRICi20847162. VBIAliAci73240_1814.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001727 Genomic DNA. Translation: ACV58876.1 .
RefSeqi WP_012811162.1. NC_013205.1.
YP_003185265.1. NC_013205.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 521098.Aaci_1864.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACV58876 ; ACV58876 ; Aaci_1864 .
GeneIDi 8425381.
KEGGi aac:Aaci_1864.
PATRICi 20847162. VBIAliAci73240_1814.

Phylogenomic databases

eggNOGi COG0322.
HOGENOMi HOG000279960.
KOi K03703.
OMAi QTIASCV.
OrthoDBi EOG6K13R9.

Enzyme and pathway databases

BioCyci AACI521098:GCIO-1923-MONOMER.

Family and domain databases

Gene3Di 3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPi MF_00203. UvrC.
InterProi IPR027299. GIY-YIG_dom.
IPR000305. GIY-YIG_SF.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
[Graphical view ]
Pfami PF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
[Graphical view ]
SMARTi SM00465. GIYc. 1 hit.
SM00278. HhH1. 1 hit.
[Graphical view ]
SUPFAMi SSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsi TIGR00194. uvrC. 1 hit.
PROSITEi PS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27009 / DSM 446 / 104-1AImported.

Entry informationi

Entry nameiC8WXQ5_ALIAD
AccessioniPrimary (citable) accession number: C8WXQ5
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: October 29, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3