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C8WXQ5

- C8WXQ5_ALIAD

UniProt

C8WXQ5 - C8WXQ5_ALIAD

Protein

UvrABC system protein C

Gene

uvrC

Organism
Alicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / 104-1A) (Bacillus acidocaldarius)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (03 Nov 2009)
      Previous versions | rss
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    Functioni

    The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotationSAAS annotation

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-HAMAP
    2. excinuclease ABC activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. nucleotide-excision repair Source: UniProtKB-HAMAP
    2. SOS response Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Excision nucleaseUniRule annotationSAAS annotation

    Keywords - Biological processi

    DNA damage, DNA excisionUniRule annotationSAAS annotation, DNA repair, SOS responseUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciAACI521098:GCIO-1923-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    UvrABC system protein CUniRule annotation
    Short name:
    Protein UvrCUniRule annotation
    Alternative name(s):
    Excinuclease ABC subunit CUniRule annotation
    Gene namesi
    Name:uvrCUniRule annotation
    Ordered Locus Names:Aaci_1864Imported
    OrganismiAlicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / 104-1A) (Bacillus acidocaldarius)Imported
    Taxonomic identifieri521098 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesAlicyclobacillaceaeAlicyclobacillus
    ProteomesiUP000001917: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. excinuclease repair complex Source: InterPro

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Interacts with UvrB in an incision complex.UniRule annotationSAAS annotation

    Protein-protein interaction databases

    STRINGi521098.Aaci_1864.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini14 – 9178GIY-YIGUniRule annotationAdd
    BLAST
    Domaini196 – 23136UVRUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the UvrC family.UniRule annotation
    Contains 1 GIY-YIG domain.UniRule annotation
    Contains 1 UVR domain.UniRule annotation
    Contains GIY-YIG domain.SAAS annotation
    Contains UVR domain.SAAS annotation

    Phylogenomic databases

    eggNOGiCOG0322.
    HOGENOMiHOG000279960.
    KOiK03703.
    OMAiQTIASCV.
    OrthoDBiEOG6K13R9.

    Family and domain databases

    Gene3Di3.40.1440.10. 1 hit.
    4.10.860.10. 1 hit.
    HAMAPiMF_00203. UvrC.
    InterProiIPR027299. GIY-YIG_dom.
    IPR000305. GIY-YIG_SF.
    IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
    IPR010994. RuvA_2-like.
    IPR001943. UVR_dom.
    IPR004791. UvrC.
    IPR001162. UvrC_homol_region.
    [Graphical view]
    PfamiPF01541. GIY-YIG. 1 hit.
    PF02151. UVR. 1 hit.
    PF08459. UvrC_HhH_N. 1 hit.
    [Graphical view]
    SMARTiSM00465. GIYc. 1 hit.
    SM00278. HhH1. 1 hit.
    [Graphical view]
    SUPFAMiSSF46600. SSF46600. 1 hit.
    SSF47781. SSF47781. 1 hit.
    SSF82771. SSF82771. 1 hit.
    TIGRFAMsiTIGR00194. uvrC. 1 hit.
    PROSITEiPS50164. GIY_YIG. 1 hit.
    PS50151. UVR. 1 hit.
    PS50165. UVRC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C8WXQ5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNQVIRDKLD LLPQRPGVYL MKGEGGEILY VGKAKVLRNR VRSYFTGTHD    50
    TKTQVLVSQI RDFEYIVTDT VAEALLLECN LIKQHQPPYN IMLRDDKSYP 100
    YIKLTKERHP RLQIVRQVKR DGAKYFGPYP NATSAQATKR LLDRLYPLRK 150
    CKTLKKQVCL YYHIHQCLAP CVYDVDEATY EAMAKEISHF LNGGHQDVVR 200
    ELEQKMQAAA ESLEFERAAE LRDLIRHIEQ VMQEQKVTWT DGIDRDVFGF 250
    AEDRGLLSVQ VFFVRNGKLI ERQVQIAPHF DDPLTDFMSF VEQFYHERVD 300
    LPKEILLPEG VPSEALAMVV DAKVLQPKRG PKRDLVDLAC ENARQALAEK 350
    IQLIDRNLDR TLGAVMELGQ VLAIQPPRRI EAFDNSNFQG VDAVSAMVVF 400
    IDGKPAKSEY RKYKIRSTQG PDDYEAIREV VRRRYSRLVR EQKPLPDLVV 450
    IDGGKGQLRA ALSVLEGELG LEIPVCGLAK DERHRTSQLF FMDEEEPVRI 500
    ERHSPAFYLL ERIQDEVHRF AVEFHRLRRS KTGFQSILDE IPGVGPERKK 550
    AILRRFGSLK AVAAAQPEDF RGLGIGDKLA REIVARVREE LAARKQADGE 600
    MEISSEAPFS 610
    Length:610
    Mass (Da):69,889
    Last modified:November 3, 2009 - v1
    Checksum:i6798D19B5FAF965B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001727 Genomic DNA. Translation: ACV58876.1.
    RefSeqiYP_003185265.1. NC_013205.1.

    Genome annotation databases

    EnsemblBacteriaiACV58876; ACV58876; Aaci_1864.
    GeneIDi8425381.
    KEGGiaac:Aaci_1864.
    PATRICi20847162. VBIAliAci73240_1814.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001727 Genomic DNA. Translation: ACV58876.1 .
    RefSeqi YP_003185265.1. NC_013205.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 521098.Aaci_1864.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACV58876 ; ACV58876 ; Aaci_1864 .
    GeneIDi 8425381.
    KEGGi aac:Aaci_1864.
    PATRICi 20847162. VBIAliAci73240_1814.

    Phylogenomic databases

    eggNOGi COG0322.
    HOGENOMi HOG000279960.
    KOi K03703.
    OMAi QTIASCV.
    OrthoDBi EOG6K13R9.

    Enzyme and pathway databases

    BioCyci AACI521098:GCIO-1923-MONOMER.

    Family and domain databases

    Gene3Di 3.40.1440.10. 1 hit.
    4.10.860.10. 1 hit.
    HAMAPi MF_00203. UvrC.
    InterProi IPR027299. GIY-YIG_dom.
    IPR000305. GIY-YIG_SF.
    IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
    IPR010994. RuvA_2-like.
    IPR001943. UVR_dom.
    IPR004791. UvrC.
    IPR001162. UvrC_homol_region.
    [Graphical view ]
    Pfami PF01541. GIY-YIG. 1 hit.
    PF02151. UVR. 1 hit.
    PF08459. UvrC_HhH_N. 1 hit.
    [Graphical view ]
    SMARTi SM00465. GIYc. 1 hit.
    SM00278. HhH1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46600. SSF46600. 1 hit.
    SSF47781. SSF47781. 1 hit.
    SSF82771. SSF82771. 1 hit.
    TIGRFAMsi TIGR00194. uvrC. 1 hit.
    PROSITEi PS50164. GIY_YIG. 1 hit.
    PS50151. UVR. 1 hit.
    PS50165. UVRC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 27009 / DSM 446 / 104-1AImported.

    Entry informationi

    Entry nameiC8WXQ5_ALIAD
    AccessioniPrimary (citable) accession number: C8WXQ5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 3, 2009
    Last sequence update: November 3, 2009
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3