C8WX63 (C8WX63_ALIAD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
3-dehydroquinate synthase HAMAP MF_00110
EC=4.2.3.4 HAMAP MF_00110

Gene names

Name:	aroB HAMAP MF_00110
Ordered Locus Names:	Aaci_1673

Organism

Alicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / 104-1A) (Bacillus acidocaldarius) [Complete proteome] [HAMAP]

Taxonomic identifier

521098 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Alicyclobacillaceae › Alicyclobacillus

Protein attributes

Sequence length	363 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110
Cofactor	Divalent metal cations By similarity. HAMAP MF_00110 NAD By similarity. HAMAP MF_00110
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110
Subunit structure	Monomer By similarity. HAMAP MF_00110
Subcellular location	Cytoplasm By similarity HAMAP MF_00110.
Sequence similarities	Belongs to the dehydroquinate synthase family. HAMAP MF_00110

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00110
Cellular component	Cytoplasm HAMAP MF_00110
Ligand	NAD HAMAP MF_00110
Molecular function	Lyase HAMAP MF_00110 EMBL ACV58685.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-dehydroquinate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C8WX63 [UniParc]. Last modified November 3, 2009. Version 1. Checksum: 295BA2A2146ACE32	FASTA	363	39,101
	10 20 30 40 50 60 MIRLEVQSSQ GAYPVLVDAG ARRFVPGLLQ ELGLAGRKIA LITDEIVQRT AFTEELAGAV 70 80 90 100 110 120 REVGREVFVL AFPAGDAHKS LATAVELYHG LLRRGFRRGD VILAVGGGVV GDLAGFVAAT 130 140 150 160 170 180 YMRGVPYVQV PTTLLAHDSA IGGKVGVNLE EGKNLVGAFY PPRAVLFDTE ALCTLDARQW 190 200 210 220 230 240 SNGMAEVIKH AIIADEILFE QLEANPLTGL GDPAAFVDIV ARAMRVKVDV VNRDERETGL 250 260 270 280 290 300 RQVLNVGHTV GHAVEQYSGY TLGHGEAVAI GLVVEAVIAA RRGLLSPADA VRIAAVLERH 310 320 330 340 350 360 GLPIRPPYAD VEAVLRLMAV DKKHTHEGWT FALPTAIGRV EICKVQPDEV RQAYEEVREG HRP

References

[1]

"The complete chromosome of Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N., Ovchinnikova G., Chertkov O., Sims D., Brettin T., Detter J.C., Han C. , Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Pukall R., Klenk H.-P., Eisen J.A. Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27009 / DSM 446 / 104-1A.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001727 Genomic DNA. Translation: ACV58685.1.
RefSeq	YP_003185074.1. NC_013205.1.
3D structure databases
ProteinModelPortal	C8WX63.
ModBase	Search...
Protein-protein interaction databases
STRING	C8WX63.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8425183.
GenomeReviews	Gene locus Aaci_1673 in contig CP001727_GR.
KEGG	aac:Aaci_1673.
PATRIC	20846768. VBIAliAci73240_1624.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	EAFKHGL.
Family and domain databases
HAMAP	MF_00110. DHQ_synthase. [Tree]
InterPro	IPR016037. DHQ_synth_AroB. [Graphical view]
KO	K01735.
PANTHER	PTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSF	PIRSF001455. DHQ_synth. 1 hit.
TIGRFAMs	TIGR01357. AroB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C8WX63_ALIAD

Accession

Primary (citable) accession number: C8WX63

Entry history

Integrated into UniProtKB/TrEMBL:	November 3, 2009
Last sequence update:	November 3, 2009
Last modified:	December 14, 2011
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)