C8WTE6 (C8WTE6_ALIAD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
3-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210 RuleBase RU000531
EC=2.5.1.19 HAMAP MF_00210 RuleBase RU000531

Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase HAMAP MF_00210

Gene names

Name:	aroA HAMAP MF_00210
Ordered Locus Names:	Aaci_0640

Organism

Alicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / 104-1A) (Bacillus acidocaldarius) [Complete proteome] [HAMAP]

Taxonomic identifier

521098 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Alicyclobacillaceae › Alicyclobacillus

Protein attributes

Sequence length	450 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210 RuleBase RU000531
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210
Subunit structure	Monomer By similarity. HAMAP MF_00210
Subcellular location	Cytoplasm By similarity HAMAP MF_00210.
Sequence similarities	Belongs to the EPSP synthase family. HAMAP MF_00210 RuleBase RU004164

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00210 RuleBase RU000531
Cellular component	Cytoplasm HAMAP MF_00210
Molecular function	Transferase HAMAP MF_00210 RuleBase RU000531 EMBL ACV57688.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-phosphoshikimate 1-carboxyvinyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C8WTE6 [UniParc]. Last modified November 3, 2009. Version 1. Checksum: D3647457C8A70B9F	FASTA	450	47,999
	10 20 30 40 50 60 MADARQGADL EARSPWALGG YQLARVGPVQ GPVDADVRVP GSKSVTNRAL VIAALAEGES 70 80 90 100 110 120 VLSGILQSDD AYWCIEALRA LGVPVEVDGD RVRMTGCGGQ FPRSDARVYT GAGGTTARFL 130 140 150 160 170 180 TAALAASRGE YEIRGSRRMN ERPMGELFRA LRVLGAEIEP LERPDTLPIR LRARGLAGGE 190 200 210 220 230 240 VAMSGAQSSQ FVSGVLIAAP YARAPVSVRI VDHIVQHAYV HITLDMMQAF GAKCEAAGDL 250 260 270 280 290 300 AVISVEPGGY RGRAYDIEAD ASTACYFFAA AAVTGGRVRV ANLTRDTRQP DVHFVDVLAK 310 320 330 340 350 360 MGCEVASSDA GIEVRGPEKL RGGFSVSMKE MSDQTLTLAF LAPFADGPIE ITGVGHIRHH 370 380 390 400 410 420 ESDRIRVIVE TLARVGVRAE EREDGVVVYP GAPRPAALPS YDDHRVAMAL SVLALRAEGI 430 440 450 EIEDPGCVSK TCPTFFHHLR EMGVLVDLVP

References

[1]

"The complete chromosome of Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N., Ovchinnikova G., Chertkov O., Sims D., Brettin T., Detter J.C., Han C. , Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Pukall R., Klenk H.-P., Eisen J.A. Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27009 / DSM 446 / 104-1A.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001727 Genomic DNA. Translation: ACV57688.1.
RefSeq	YP_003184077.1. NC_013205.1.
3D structure databases
ProteinModelPortal	C8WTE6.
ModBase	Search...
Protein-protein interaction databases
STRING	C8WTE6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8424131.
GenomeReviews	Gene locus Aaci_0640 in contig CP001727_GR.
KEGG	aac:Aaci_0640.
PATRIC	20844734. VBIAliAci73240_0628.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	GADIEWG.
ProtClustDB	PRK02427.
Family and domain databases
HAMAP	MF_00210. EPSP_synth. [Tree]
InterPro	IPR001986. Enolpyruvate_Tfrase_dom. IPR006264. EPSP_synthase. IPR023193. EPSP_synthase_CS. IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b. [Graphical view]
Gene3D	G3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KO	K00800.
Pfam	PF00275. EPSP_synthase. 1 hit. [Graphical view]
PIRSF	PIRSF000505. EPSPS. 1 hit.
SUPFAM	SSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMs	TIGR01356. AroA. 1 hit.
PROSITE	PS00885. EPSP_SYNTHASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C8WTE6_ALIAD

Accession

Primary (citable) accession number: C8WTE6

Entry history

Integrated into UniProtKB/TrEMBL:	November 3, 2009
Last sequence update:	November 3, 2009
Last modified:	December 14, 2011
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)