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C8WRU4 (C8WRU4_ALIAD) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length432 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
C8WRU4 [UniParc].

Last modified November 3, 2009. Version 1.
Checksum: 2A458EC5689FB640

FASTA43247,978
        10         20         30         40         50         60 
MPTFERYQLP TEGEPITLVD GKLNVPDHPI IPFIEGDGTG PDIWRAAQRV FDAAVEKAYG 

        70         80         90        100        110        120 
GKRKIAWYEV YAGEKAYNMF GEWLPQDTLT ALSEYIVSIK GPLTTPVGGG IRSLNVAVRQ 

       130        140        150        160        170        180 
ELDLYVCQRP VRYFQGVPSP VKHPELVDMV IFRENSEDIY AGIEWQAGTP EVKKVIEFLQ 

       190        200        210        220        230        240 
KEMGVKKIRF PETSGIGVKP VSREGTERLV RAAIEYALRH KRKSVTLVHK GNIMKFTEGA 

       250        260        270        280        290        300 
FKNWGYELAE REFSDKVFTW AQYDRIKAEK GQEAADAAQK EAIEAGKLIV KDVIADAFLQ 

       310        320        330        340        350        360 
QILTRPAEYD VIATLNLNGD YISDALAAQV GGIGIAPGAN INYETGHAVF EATHGTAPKY 

       370        380        390        400        410        420 
AGLDKVNPGS VILSGVMMFE YMGWQEAADL ITRAMEKTIA QKIVTYDFAR LMEGATEVKC 

       430 
SEFGDHIIQN MG 

« Hide

References

[1]"The complete chromosome of Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446."
US DOE Joint Genome Institute (JGI-PGF)
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N., Ovchinnikova G., Chertkov O., Sims D., Brettin T., Detter J.C., Han C. expand/collapse author list , Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Pukall R., Klenk H.-P., Eisen J.A.
Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 27009 / DSM 446 / 104-1A.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001727 Genomic DNA. Translation: ACV59355.1.
RefSeqYP_003185744.1. NC_013205.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING521098.Aaci_2348.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACV59355; ACV59355; Aaci_2348.
GeneID8425877.
KEGGaac:Aaci_2348.
PATRIC20848190. VBIAliAci73240_2318.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0538.
HOGENOMHOG000021113.
KOK00031.
OMACLRPIRY.
OrthoDBEOG6SNDTP.

Enzyme and pathway databases

BioCycAACI521098:GCIO-2419-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC8WRU4_ALIAD
AccessionPrimary (citable) accession number: C8WRU4
Entry history
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: May 14, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)