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Protein

Xylose isomerase

Gene

xylA

Organism
Alicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / JCM 5260 / NBRC 15652 / NCIMB 11725 / NRRL B-14509 / 104-1A) (Bacillus acidocaldarius)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei102UniRule annotation1
Active sitei105UniRule annotation1
Metal bindingi233Magnesium 1UniRule annotation1
Metal bindingi269Magnesium 1UniRule annotation1
Metal bindingi269Magnesium 2UniRule annotation1
Metal bindingi272Magnesium 2UniRule annotation1
Metal bindingi297Magnesium 1UniRule annotation1
Metal bindingi308Magnesium 2UniRule annotation1
Metal bindingi310Magnesium 2UniRule annotation1
Metal bindingi340Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processCarbohydrate metabolism, Xylose metabolismUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciAACI521098:G1GFZ-2209-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotationSAAS annotation (EC:5.3.1.5UniRule annotationSAAS annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:Aaci_2180Imported
OrganismiAlicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / JCM 5260 / NBRC 15652 / NCIMB 11725 / NRRL B-14509 / 104-1A) (Bacillus acidocaldarius)Imported
Taxonomic identifieri521098 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesAlicyclobacillaceaeAlicyclobacillus
Proteomesi

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi521098.Aaci_2180

Structurei

3D structure databases

ProteinModelPortaliC8WR20
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini96 – 285AP_endonuc_2InterPro annotationAdd BLAST190

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili113 – 133Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105C93 Bacteria
COG2115 LUCA
HOGENOMiHOG000252293
KOiK01805
OMAiHTFQHEL
OrthoDBiPOG091H07LC

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013022 Xyl_isomerase-like_TIM-brl
IPR013452 Xylose_isom_bac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PfamiView protein in Pfam
PF01261 AP_endonuc_2, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02630 xylose_isom_A, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

C8WR20-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDVATYFPEV TRIAYEGKRS DNPLSFKYYN PDEIVLGKPM KEHLRFSVAY
60 70 80 90 100
WHTFTLSGAD PFGLPNMIRP WDGATGMDLA KRRVEAAFEF MTKLGVEYFC
110 120 130 140 150
FHDRDIAPEG DTLRETNRNL DEIVALIKEY MQSTGIKLLW NTQNLFSNPR
160 170 180 190 200
FAHGAATAPD ADVFAYAAAQ VKKSLEIAKE LGAENYVFWG GREGYETLLN
210 220 230 240 250
TDLKLELDNY ARLLQMAVDY ADEIGFTGQF LIEPKPKEPT KHQYDFDVQS
260 270 280 290 300
GLAFLYHYGL KDRFKFNIEA NHATLAGHTF QHELRFARIH GLLGSVDANQ
310 320 330 340 350
GDPLLGWDTD EFPTNLYETT LAMYEILLNG GLAPGGLNFD AKVRRASMTP
360 370 380 390 400
IDLFYGHIAG MDSFARGLKV AAKLLEDRVF EREIEERYES YRTGIGKDIV
410 420 430 440
EGRATLKSLE SYVIDKRVTA TRSGRQEVLL AKLNQYLLET E
Length:441
Mass (Da):50,094
Last modified:November 3, 2009 - v1
Checksum:iFE0920E34DE4394E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001727 Genomic DNA Translation: ACV59189.1
RefSeqiWP_012811447.1, NC_013205.1

Genome annotation databases

EnsemblBacteriaiACV59189; ACV59189; Aaci_2180
KEGGiaac:Aaci_2180

Similar proteinsi

Entry informationi

Entry nameiC8WR20_ALIAD
AccessioniPrimary (citable) accession number: C8WR20
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: May 23, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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