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C8WN09

- C8WN09_EGGLE

UniProt

C8WN09 - C8WN09_EGGLE

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Protein
Alanine racemase
Gene
Elen_2785
Organism
Eggerthella lenta (strain ATCC 25559 / DSM 2243 / JCM 9979 / NCTC 11813 / VPI 0255) (Eubacterium lentum)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei100 – 1001Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei198 – 1981Substrate By similarityUniRule annotation
Active sitei327 – 3271Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei375 – 3751Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciELEN479437:GHWY-2836-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Elen_2785Imported
OrganismiEggerthella lenta (strain ATCC 25559 / DSM 2243 / JCM 9979 / NCTC 11813 / VPI 0255) (Eubacterium lentum)Imported
Taxonomic identifieri479437 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCoriobacteridaeCoriobacterialesCoriobacterineaeCoriobacteriaceaeEggerthella
ProteomesiUP000001377: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei100 – 1001N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi479437.Elen_2785.

Structurei

3D structure databases

ProteinModelPortaliC8WN09.

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031444.
KOiK01775.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C8WN09-1 [UniParc]FASTAAdd to Basket

« Hide

MGTPRYVGEQ PPAGNAANKG AYEAATAAFS SGAEGAFQYA RDHARPDGEP    50
AQFDPDKLRL IPDVDRRWSW TEIDLNAIRH NTSAVKQRID NGVRLMAVVK 100
ADGYGHGAVR CAKTALNSGA DYLGVATVNE AIELREALVN APILVLSQPP 150
ETAIPLLLAY KVMPSVYTSE FAIQYAEAAD AYGVRAPYHL AVNTGMNRIG 200
VRHDEVVEFM GQVSFHRALD LVGTFTHFAT ADSAETLDFQ IQVKRFIEAV 250
TALRTAGVNP GIVHAANSAA AIRYPDVQFD MVRLGIAMYG LHPSGVTRPM 300
IDLHPAMSVH ARITDVRTVP MSEGVSYGMN YRSPGSVKIC TVPVGYADGL 350
RRGLSGRTDV ILKGQRCHQV GNICMDQCMF EVDLRVYGSR RRLDPMIGDE 400
VLLVGREGDS VITLDDMANT LGTINYELAC GFSLRMPRVY V 441
Length:441
Mass (Da):47,990
Last modified:November 3, 2009 - v1
Checksum:iD53B377D9FCFAAEA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001726 Genomic DNA. Translation: ACV56732.1.
RefSeqiYP_003183121.1. NC_013204.1.

Genome annotation databases

EnsemblBacteriaiACV56732; ACV56732; Elen_2785.
GeneIDi8417111.
KEGGiele:Elen_2785.
PATRICi21846353. VBIEggLen106823_2859.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001726 Genomic DNA. Translation: ACV56732.1 .
RefSeqi YP_003183121.1. NC_013204.1.

3D structure databases

ProteinModelPortali C8WN09.
ModBasei Search...

Protein-protein interaction databases

STRINGi 479437.Elen_2785.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACV56732 ; ACV56732 ; Elen_2785 .
GeneIDi 8417111.
KEGGi ele:Elen_2785.
PATRICi 21846353. VBIEggLen106823_2859.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000031444.
KOi K01775.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci ELEN479437:GHWY-2836-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25559 / DSM 2243 / JCM 9979 / NCTC 11813 / VPI 0255.

Entry informationi

Entry nameiC8WN09_EGGLE
AccessioniPrimary (citable) accession number: C8WN09
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: July 9, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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