ID   C8WKS1_EGGLE            Unreviewed;       454 AA.
AC   C8WKS1;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   SubName: Full=Metal dependent phosphohydrolase {ECO:0000313|EMBL:ACV54377.1};
GN   OrderedLocusNames=Elen_0387 {ECO:0000313|EMBL:ACV54377.1};
OS   Eggerthella lenta (strain ATCC 25559 / DSM 2243 / CCUG 17323 / JCM 9979 /
OS   KCTC 3265 / NCTC 11813 / VPI 0255 / 1899 B) (Eubacterium lentum).
OC   Bacteria; Actinomycetota; Coriobacteriia; Eggerthellales; Eggerthellaceae;
OC   Eggerthella.
OX   NCBI_TaxID=479437 {ECO:0000313|EMBL:ACV54377.1, ECO:0000313|Proteomes:UP000001377};
RN   [1] {ECO:0000313|EMBL:ACV54377.1, ECO:0000313|Proteomes:UP000001377}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25559 / DSM 2243 / CCUG 17323 / JCM 9979 / KCTC 3265 /
RC   NCTC 11813 / VPI 0255 / 1899 B {ECO:0000313|Proteomes:UP000001377};
RX   PubMed=21304654; DOI=10.4056/sigs.33592;
RA   Saunders E., Pukall R., Abt B., Lapidus A., Glavina Del Rio T.,
RA   Copeland A., Tice H., Cheng J.F., Lucas S., Chen F., Nolan M., Bruce D.,
RA   Goodwin L., Pitluck S., Ivanova N., Mavromatis K., Ovchinnikova G.,
RA   Pati A., Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J.,
RA   Jeffries C.D., Chain P., Meincke L., Sims D., Brettin T., Detter J.C.,
RA   Goker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA   Kyrpides N.C., Klenk H.P., Han C.;
RT   "Complete genome sequence of Eggerthella lenta type strain (IPP VPI
RT   0255).";
RL   Stand. Genomic Sci. 1:174-182(2009).
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DR   EMBL; CP001726; ACV54377.1; -; Genomic_DNA.
DR   AlphaFoldDB; C8WKS1; -.
DR   STRING; 479437.Elen_0387; -.
DR   PaxDb; 479437-Elen_0387; -.
DR   KEGG; ele:Elen_0387; -.
DR   eggNOG; COG2206; Bacteria.
DR   HOGENOM; CLU_040286_2_0_11; -.
DR   Proteomes; UP000001377; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd00077; HDc; 2.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 2.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR037522; HD_GYP_dom.
DR   PANTHER; PTHR43155:SF2; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108; 1.
DR   PANTHER; PTHR43155; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108-RELATED; 1.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF13487; HD_5; 1.
DR   SMART; SM00471; HDc; 2.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 2.
DR   PROSITE; PS51832; HD_GYP; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ACV54377.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001377}.
FT   DOMAIN          227..422
FT                   /note="HD-GYP"
FT                   /evidence="ECO:0000259|PROSITE:PS51832"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   454 AA;  50352 MW;  E49ADF2A971E22B7 CRC64;
     MSESGKTYAG GPTVSRRSRF SHPEGFDDGL SIIAVSIMVQ RALNCVDPRL VDHGLRVAAV
     LDAMLEAKGV TDPTQRRAAY LVALLHDVGA YRTEEIDRMV AFETESVWEH SFYGYLFFKE
     LTPLGAYADV ILYHHLPYDR FTDQDPYVKF LAGAVHVADR VDVLLLERPQ ADVVEVERLL
     AASRPGAFSP EAVALFFEAQ RRFDVLARLR SGVKQPDRSH IVDDPDGTGS ASSFLDMLVH
     VIDFRSRHTV THTVTTAWVA YELALRLIGD QRAAARVYTS ALVHDVGKIG IPLSILEKPG
     KLDDEEMKVM RTHVELTEDI LEGCIEPVLL QAAARHHEKL DGSGYPRGLH AAELSMPDRI
     IAVADIVSAL VGTRSYKKAY PKEKVLELLA WHVETGKIDC IVVETMTRDY DAIMLSVAAA
     CQPVAAAYER VQSAYALMLG KLKRWQAENE GRSA
//