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C8WJE1

- C8WJE1_EGGLE

UniProt

C8WJE1 - C8WJE1_EGGLE

Protein

Glutamate decarboxylase

Gene

Elen_0149

Organism
Eggerthella lenta (strain ATCC 25559 / DSM 2243 / JCM 9979 / NCTC 11813 / VPI 0255) (Eubacterium lentum)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (03 Nov 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. glutamate decarboxylase activity Source: InterPro
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. glutamate metabolic process Source: InterPro

    Keywords - Molecular functioni

    DecarboxylaseUniRule annotation, Lyase

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Enzyme and pathway databases

    BioCyciELEN479437:GHWY-158-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
    Gene namesi
    Ordered Locus Names:Elen_0149Imported
    OrganismiEggerthella lenta (strain ATCC 25559 / DSM 2243 / JCM 9979 / NCTC 11813 / VPI 0255) (Eubacterium lentum)Imported
    Taxonomic identifieri479437 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaCoriobacteridaeCoriobacterialesCoriobacterineaeCoriobacteriaceaeEggerthella
    ProteomesiUP000001377: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi479437.Elen_0149.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0076.
    HOGENOMiHOG000070228.
    KOiK01580.
    OrthoDBiEOG6TFCPW.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    InterProiIPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view]
    PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    C8WJE1-1 [UniParc]FASTAAdd to Basket

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    MKEQTSTSKI LDSMDEGTKY STPIFGSEAS DVAMPRLKMN DKPVEPRITY    50
    EMIKEYLSIE GNATQNLTTF CQTYMEPMAT KIMAETMEKN AIDKDEYPMT 100
    ADLENRCVAM IGNLWHADPA EEPMGTSTVG SSEACMLGGL GMLFRWKKLA 150
    KDAGIDIYTA QRPNLVISAG YQVCWEKFCR YWDIEMRLVP LEKDHLSLNM 200
    DTVMDYVDDH TIGIAAILGI TYTGKFDDVQ KLDELVEAYN QQHPKLPIRI 250
    HVDGASGGMF APFVEPDLVW DFQLKNVWSI NCSGHKYGLV YPGIGWVVWR 300
    SKEALPEDLI FWVSYLGGEE ATMAINFSRS ASQIVGQYYV LMRNGFEGFK 350
    EIQERTLDVA RYLAAELKEM GVFEIYEDAS HIPIVCWGLK DDAGVEWSLY 400
    DLSDRLRMSG WLVPAYPMPA DMQDTTVQRV VARADFSMQL AIKLVEDMKK 450
    EMDTLNKAKF VTGNTQGVIR TGFNHGGRSA VDKGEKVQTK APTPQK 496
    Length:496
    Mass (Da):55,965
    Last modified:November 3, 2009 - v1
    Checksum:i4615E18F418E7729
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001726 Genomic DNA. Translation: ACV54143.1.
    RefSeqiWP_015759836.1. NC_013204.1.
    YP_003180532.1. NC_013204.1.

    Genome annotation databases

    EnsemblBacteriaiACV54143; ACV54143; Elen_0149.
    GeneIDi8414433.
    KEGGiele:Elen_0149.
    PATRICi21840878. VBIEggLen106823_0158.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001726 Genomic DNA. Translation: ACV54143.1 .
    RefSeqi WP_015759836.1. NC_013204.1.
    YP_003180532.1. NC_013204.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 479437.Elen_0149.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACV54143 ; ACV54143 ; Elen_0149 .
    GeneIDi 8414433.
    KEGGi ele:Elen_0149.
    PATRICi 21840878. VBIEggLen106823_0158.

    Phylogenomic databases

    eggNOGi COG0076.
    HOGENOMi HOG000070228.
    KOi K01580.
    OrthoDBi EOG6TFCPW.

    Enzyme and pathway databases

    BioCyci ELEN479437:GHWY-158-MONOMER.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    InterProi IPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view ]
    PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 25559 / DSM 2243 / JCM 9979 / NCTC 11813 / VPI 0255Imported.

    Entry informationi

    Entry nameiC8WJE1_EGGLE
    AccessioniPrimary (citable) accession number: C8WJE1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 3, 2009
    Last sequence update: November 3, 2009
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3