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C8WJE1

- C8WJE1_EGGLE

UniProt

C8WJE1 - C8WJE1_EGGLE

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Protein

Glutamate decarboxylase

Gene

Elen_0149

Organism
Eggerthella lenta (strain ATCC 25559 / DSM 2243 / JCM 9979 / NCTC 11813 / VPI 0255) (Eubacterium lentum)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

Pyridoxal phosphate.UniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciELEN479437:GHWY-158-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:Elen_0149Imported
OrganismiEggerthella lenta (strain ATCC 25559 / DSM 2243 / JCM 9979 / NCTC 11813 / VPI 0255) (Eubacterium lentum)Imported
Taxonomic identifieri479437 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCoriobacteridaeCoriobacterialesCoriobacterineaeCoriobacteriaceaeEggerthella
ProteomesiUP000001377: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi479437.Elen_0149.

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OrthoDBiEOG6TFCPW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

C8WJE1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKEQTSTSKI LDSMDEGTKY STPIFGSEAS DVAMPRLKMN DKPVEPRITY
60 70 80 90 100
EMIKEYLSIE GNATQNLTTF CQTYMEPMAT KIMAETMEKN AIDKDEYPMT
110 120 130 140 150
ADLENRCVAM IGNLWHADPA EEPMGTSTVG SSEACMLGGL GMLFRWKKLA
160 170 180 190 200
KDAGIDIYTA QRPNLVISAG YQVCWEKFCR YWDIEMRLVP LEKDHLSLNM
210 220 230 240 250
DTVMDYVDDH TIGIAAILGI TYTGKFDDVQ KLDELVEAYN QQHPKLPIRI
260 270 280 290 300
HVDGASGGMF APFVEPDLVW DFQLKNVWSI NCSGHKYGLV YPGIGWVVWR
310 320 330 340 350
SKEALPEDLI FWVSYLGGEE ATMAINFSRS ASQIVGQYYV LMRNGFEGFK
360 370 380 390 400
EIQERTLDVA RYLAAELKEM GVFEIYEDAS HIPIVCWGLK DDAGVEWSLY
410 420 430 440 450
DLSDRLRMSG WLVPAYPMPA DMQDTTVQRV VARADFSMQL AIKLVEDMKK
460 470 480 490
EMDTLNKAKF VTGNTQGVIR TGFNHGGRSA VDKGEKVQTK APTPQK
Length:496
Mass (Da):55,965
Last modified:November 3, 2009 - v1
Checksum:i4615E18F418E7729
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001726 Genomic DNA. Translation: ACV54143.1.
RefSeqiWP_015759836.1. NC_013204.1.
YP_003180532.1. NC_013204.1.

Genome annotation databases

EnsemblBacteriaiACV54143; ACV54143; Elen_0149.
GeneIDi8414433.
KEGGiele:Elen_0149.
PATRICi21840878. VBIEggLen106823_0158.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001726 Genomic DNA. Translation: ACV54143.1 .
RefSeqi WP_015759836.1. NC_013204.1.
YP_003180532.1. NC_013204.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 479437.Elen_0149.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACV54143 ; ACV54143 ; Elen_0149 .
GeneIDi 8414433.
KEGGi ele:Elen_0149.
PATRICi 21840878. VBIEggLen106823_0158.

Phylogenomic databases

eggNOGi COG0076.
HOGENOMi HOG000070228.
KOi K01580.
OrthoDBi EOG6TFCPW.

Enzyme and pathway databases

BioCyci ELEN479437:GHWY-158-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
InterProi IPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
Pfami PF00282. Pyridoxal_deC. 1 hit.
[Graphical view ]
SUPFAMi SSF53383. SSF53383. 1 hit.
TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25559 / DSM 2243 / JCM 9979 / NCTC 11813 / VPI 0255Imported.

Entry informationi

Entry nameiC8WJE1_EGGLE
AccessioniPrimary (citable) accession number: C8WJE1
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: October 29, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3