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Protein

Guanylate kinase

Gene

gmk

Organism
Eggerthella lenta (strain ATCC 25559 / DSM 2243 / JCM 9979 / NCTC 11813 / VPI 0255) (Eubacterium lentum)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotationSAAS annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi11 – 18ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinaseUniRule annotationSAAS annotationImported, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotationSAAS annotation (EC:2.7.4.8UniRule annotationSAAS annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:Elen_1660Imported
OrganismiEggerthella lenta (strain ATCC 25559 / DSM 2243 / JCM 9979 / NCTC 11813 / VPI 0255) (Eubacterium lentum)Imported
Taxonomic identifieri479437 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCoriobacteriiaEggerthellalesEggerthellaceaeEggerthella
Proteomesi
  • UP000001377 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi479437.Elen_1660.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 182Guanylate kinase-likeInterPro annotationAdd BLAST179

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4108UHA. Bacteria.
COG0194. LUCA.
HOGENOMiHOG000037640.
KOiK00942.
OMAiYGTLKSE.
OrthoDBiPOG091H01Q4.

Family and domain databases

HAMAPiMF_00328. Guanylate_kinase. 1 hit.
InterProiView protein in InterPro
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR017665. Guanylate_kinase.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
SMARTiView protein in SMART
SM00072. GuKc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
PROSITEiView protein in PROSITE
PS50052. GUANYLATE_KINASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

C8WHN7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRHGNLFVIS GPSGAGKGTL VARLLREIPD AWVSMSVTTR KPREGEVDGV
60 70 80 90 100
HYRFASPEEF QELVDEDGLL EWATYGGNCY GTPRATVEEH IACGDQVILE
110 120 130 140 150
IDVQGGFQVR DKFPSAHLVF IEPPSLDVLE ARLRGRGTET EEAIATRMET
160 170 180 190
ARVELSRKME YDIRLVNDDL DEAVRALAGY VNEQAEKIRG
Length:190
Mass (Da):21,147
Last modified:November 3, 2009 - v1
Checksum:i12D21F4FD291574F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001726 Genomic DNA. Translation: ACV55628.1.
RefSeqiWP_009608702.1. NC_013204.1.

Genome annotation databases

EnsemblBacteriaiACV55628; ACV55628; Elen_1660.
KEGGiele:Elen_1660.

Similar proteinsi

Entry informationi

Entry nameiC8WHN7_EGGLE
AccessioniPrimary (citable) accession number: C8WHN7
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: September 27, 2017
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported