C8WBE0 (C8WBE0_ZYMMN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
tRNA pseudouridine synthase A HAMAP-Rule MF_00171
EC=5.4.99.12 HAMAP-Rule MF_00171

Alternative name(s):
tRNA pseudouridine(38-40) synthase HAMAP-Rule MF_00171
tRNA pseudouridylate synthase I HAMAP-Rule MF_00171
tRNA-uridine isomerase I HAMAP-Rule MF_00171

Gene names

Name:	truA HAMAP-Rule MF_00171
Ordered Locus Names:	Za10_0476 EMBL ACV75026.1

Organism

Zymomonas mobilis subsp. mobilis (strain NCIB 11163) [Complete proteome] [HAMAP] EMBL ACV75026.1

Taxonomic identifier

622759 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Sphingomonadaceae › Zymomonas › Zymomonas mobilis › Zymomonas mobilis subsp. mobilis

Protein attributes

Sequence length	245 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs By similarity. HAMAP-Rule MF_00171 SAAS SAAS020094
Catalytic activity	tRNA uridine = tRNA pseudouridine. RuleBase RU003792 tRNA uridine(38-40) = tRNA pseudouridine(38-40). HAMAP-Rule MF_00171 SAAS SAAS020094
Subunit structure	Homodimer By similarity. HAMAP-Rule MF_00171
Sequence similarities	Belongs to the tRNA pseudouridine synthase TruA family. HAMAP-Rule MF_00171 RuleBase RU003792

Ontologies

Keywords
Biological process	tRNA processing HAMAP-Rule MF_00171 SAAS SAAS020094 RuleBase RU003792
Molecular function	Isomerase HAMAP-Rule MF_00171 SAAS SAAS020094 RuleBase RU003792 EMBL ACV75026.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tRNA pseudouridine synthesis Inferred from electronic annotation. Source: HAMAP
Molecular_function	RNA binding Inferred from electronic annotation. Source: InterPro pseudouridine synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	52	1	Nucleophile By similarity HAMAP-Rule MF_00171
	Binding site	111	1	Substrate By similarity HAMAP-Rule MF_00171

Sequences

	Sequence		Length	Mass (Da)
	C8WBE0 [UniParc]. Last modified November 3, 2009. Version 1. Checksum: 6DE58C360928D760	FASTA	245	27,412
	10 20 30 40 50 60 MNRYRLTVEF DGRNFMGWQR QKHGATIQGS IEEAGASIAG QPTPVQAAGR TDAGVHGLAM 70 80 90 100 110 120 TAHIDVARDF TPFRLMEALN ARLKPRPIAI LSCEQVDPEW HARFSCIGRR YLYRIINRRP 130 140 150 160 170 180 PLTLEAGRAW HVIKPLDAET MDIAAKRLIG LHDFTTFRSV HCQSKSPVKT LDHLDVRRIG 190 200 210 220 230 240 DQIEITAAAR SFLHHQVRSM VGCLVLVGQG QWTADDMTTA LEARNRAALG FNAPPDGLYF TQAIY

References

[1]

"Complete genome sequence of the ethanol producer Zymomonas mobilis NCIMB 11163." Kouvelis V.N., Saunders E., Brettin T.S., Bruce D., Detter C., Han C., Typas M.A., Pappas K.M. J. Bacteriol. 191:7140-7141(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCIB 11163.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001722 Genomic DNA. Translation: ACV75026.1.
RefSeq	YP_003225610.1. NC_013355.1.
3D structure databases
ProteinModelPortal	C8WBE0.
ModBase	Search...
Protein-protein interaction databases
STRING	622759.Za10_0476.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACV75026; ACV75026; Za10_0476.
GeneID	8471570.
KEGG	zmn:Za10_0476.
PATRIC	24154002. VBIZymMob135463_0532.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0101.
HOGENOM	HOG000248672.
KO	K06173.
ProtClustDB	PRK00021.
Family and domain databases
Gene3D	3.30.70.580. 1 hit. 3.30.70.660. 1 hit.
HAMAP	MF_00171. TruA.
InterPro	IPR020103. PsdUridine_synth_cat_dom. IPR001406. PsdUridine_synth_TruA. IPR020097. PsdUridine_synth_TruA_a/b_dom. IPR020095. PsdUridine_synth_TruA_C. IPR020094. PsdUridine_synth_TruA_N. [Graphical view]
PANTHER	PTHR11142. PTHR11142. 1 hit.
Pfam	PF01416. PseudoU_synth_1. 2 hits. [Graphical view]
PIRSF	PIRSF001430. tRNA_psdUrid_synth. 1 hit.
SUPFAM	SSF55120. PsdUridine_synth_cat_dom. 1 hit.
TIGRFAMs	TIGR00071. hisT_truA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C8WBE0_ZYMMN

Accession

Primary (citable) accession number: C8WBE0

Entry history

Integrated into UniProtKB/TrEMBL:	November 3, 2009
Last sequence update:	November 3, 2009
Last modified:	May 1, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)