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C8WBE0 (C8WBE0_ZYMMN) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
tRNA pseudouridine synthase A HAMAP-Rule MF_00171

EC=5.4.99.12 HAMAP-Rule MF_00171
Alternative name(s):
tRNA pseudouridine(38-40) synthase HAMAP-Rule MF_00171
tRNA pseudouridylate synthase I HAMAP-Rule MF_00171
tRNA-uridine isomerase I HAMAP-Rule MF_00171
Gene names
Name:truA HAMAP-Rule MF_00171
Ordered Locus Names:Za10_0476 EMBL ACV75026.1
OrganismZymomonas mobilis subsp. mobilis (strain NCIB 11163) [Complete proteome] [HAMAP] EMBL ACV75026.1
Taxonomic identifier622759 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeZymomonas

Protein attributes

Sequence length245 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs By similarity. HAMAP-Rule MF_00171 SAAS SAAS020097

Catalytic activity

tRNA uridine(38-40) = tRNA pseudouridine(38-40). HAMAP-Rule MF_00171 RuleBase RU003792 SAAS SAAS020097

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00171

Sequence similarities

Belongs to the tRNA pseudouridine synthase TruA family. HAMAP-Rule MF_00171 RuleBase RU003792

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site521Nucleophile By similarity HAMAP-Rule MF_00171 PIRSR PIRSR001430-1
Binding site1111Substrate By similarity HAMAP-Rule MF_00171 PIRSR PIRSR001430-2

Sequences

Sequence LengthMass (Da)Tools
C8WBE0 [UniParc].

Last modified November 3, 2009. Version 1.
Checksum: 6DE58C360928D760

FASTA24527,412
        10         20         30         40         50         60 
MNRYRLTVEF DGRNFMGWQR QKHGATIQGS IEEAGASIAG QPTPVQAAGR TDAGVHGLAM 

        70         80         90        100        110        120 
TAHIDVARDF TPFRLMEALN ARLKPRPIAI LSCEQVDPEW HARFSCIGRR YLYRIINRRP 

       130        140        150        160        170        180 
PLTLEAGRAW HVIKPLDAET MDIAAKRLIG LHDFTTFRSV HCQSKSPVKT LDHLDVRRIG 

       190        200        210        220        230        240 
DQIEITAAAR SFLHHQVRSM VGCLVLVGQG QWTADDMTTA LEARNRAALG FNAPPDGLYF 


TQAIY 

« Hide

References

[1]"Complete genome sequence of the ethanol producer Zymomonas mobilis NCIMB 11163."
Kouvelis V.N., Saunders E., Brettin T.S., Bruce D., Detter C., Han C., Typas M.A., Pappas K.M.
J. Bacteriol. 191:7140-7141(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NCIB 11163.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001722 Genomic DNA. Translation: ACV75026.1.
RefSeqYP_003225610.1. NC_013355.1.

3D structure databases

ProteinModelPortalC8WBE0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING622759.Za10_0476.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACV75026; ACV75026; Za10_0476.
GeneID8471570.
KEGGzmn:Za10_0476.
PATRIC24154002. VBIZymMob135463_0532.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0101.
HOGENOMHOG000248672.
KOK06173.
OrthoDBEOG6Z9B4R.

Enzyme and pathway databases

BioCycZMOB622759:GI1C-590-MONOMER.

Family and domain databases

Gene3D3.30.70.580. 1 hit.
3.30.70.660. 1 hit.
HAMAPMF_00171. TruA.
InterProIPR020103. PsdUridine_synth_cat_dom.
IPR001406. PsdUridine_synth_TruA.
IPR020097. PsdUridine_synth_TruA_a/b_dom.
IPR020095. PsdUridine_synth_TruA_C.
IPR020094. PsdUridine_synth_TruA_N.
[Graphical view]
PANTHERPTHR11142. PTHR11142. 1 hit.
PfamPF01416. PseudoU_synth_1. 2 hits.
[Graphical view]
PIRSFPIRSF001430. tRNA_psdUrid_synth. 1 hit.
SUPFAMSSF55120. SSF55120. 1 hit.
TIGRFAMsTIGR00071. hisT_truA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC8WBE0_ZYMMN
AccessionPrimary (citable) accession number: C8WBE0
Entry history
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: June 11, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)