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C8WBE0

- C8WBE0_ZYMMN

UniProt

C8WBE0 - C8WBE0_ZYMMN

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Protein

tRNA pseudouridine synthase A

Gene

truA

Organism
Zymomonas mobilis subsp. mobilis (strain NCIB 11163)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.UniRule annotationSAAS annotation

Catalytic activityi

tRNA uridine(38-40) = tRNA pseudouridine(38-40).UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei52 – 521NucleophileUniRule annotation
Binding sitei111 – 1111SubstrateUniRule annotation

GO - Molecular functioni

  1. pseudouridine synthase activity Source: UniProtKB-HAMAP
  2. RNA binding Source: InterPro

GO - Biological processi

  1. tRNA pseudouridine synthesis Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

tRNA processingUniRule annotation

Enzyme and pathway databases

BioCyciZMOB622759:GI1C-590-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase AUniRule annotation (EC:5.4.99.12UniRule annotation)
Alternative name(s):
tRNA pseudouridine(38-40) synthaseUniRule annotation
tRNA pseudouridylate synthase IUniRule annotation
tRNA-uridine isomerase IUniRule annotation
Gene namesi
Name:truAUniRule annotation
Ordered Locus Names:Za10_0476Imported
OrganismiZymomonas mobilis subsp. mobilis (strain NCIB 11163)Imported
Taxonomic identifieri622759 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeZymomonas
ProteomesiUP000000319: Chromosome

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi622759.Za10_0476.

Structurei

3D structure databases

ProteinModelPortaliC8WBE0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tRNA pseudouridine synthase TruA family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0101.
HOGENOMiHOG000248672.
KOiK06173.
OrthoDBiEOG6Z9B4R.

Family and domain databases

Gene3Di3.30.70.580. 1 hit.
3.30.70.660. 1 hit.
HAMAPiMF_00171. TruA.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR001406. PsdUridine_synth_TruA.
IPR020097. PsdUridine_synth_TruA_a/b_dom.
IPR020095. PsdUridine_synth_TruA_C.
IPR020094. PsdUridine_synth_TruA_N.
[Graphical view]
PANTHERiPTHR11142. PTHR11142. 1 hit.
PfamiPF01416. PseudoU_synth_1. 2 hits.
[Graphical view]
PIRSFiPIRSF001430. tRNA_psdUrid_synth. 1 hit.
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00071. hisT_truA. 1 hit.

Sequencei

Sequence statusi: Complete.

C8WBE0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNRYRLTVEF DGRNFMGWQR QKHGATIQGS IEEAGASIAG QPTPVQAAGR
60 70 80 90 100
TDAGVHGLAM TAHIDVARDF TPFRLMEALN ARLKPRPIAI LSCEQVDPEW
110 120 130 140 150
HARFSCIGRR YLYRIINRRP PLTLEAGRAW HVIKPLDAET MDIAAKRLIG
160 170 180 190 200
LHDFTTFRSV HCQSKSPVKT LDHLDVRRIG DQIEITAAAR SFLHHQVRSM
210 220 230 240
VGCLVLVGQG QWTADDMTTA LEARNRAALG FNAPPDGLYF TQAIY
Length:245
Mass (Da):27,412
Last modified:November 3, 2009 - v1
Checksum:i6DE58C360928D760
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001722 Genomic DNA. Translation: ACV75026.1.
RefSeqiYP_003225610.1. NC_013355.1.

Genome annotation databases

EnsemblBacteriaiACV75026; ACV75026; Za10_0476.
GeneIDi8471570.
KEGGizmn:Za10_0476.
PATRICi24154002. VBIZymMob135463_0532.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001722 Genomic DNA. Translation: ACV75026.1 .
RefSeqi YP_003225610.1. NC_013355.1.

3D structure databases

ProteinModelPortali C8WBE0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 622759.Za10_0476.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACV75026 ; ACV75026 ; Za10_0476 .
GeneIDi 8471570.
KEGGi zmn:Za10_0476.
PATRICi 24154002. VBIZymMob135463_0532.

Phylogenomic databases

eggNOGi COG0101.
HOGENOMi HOG000248672.
KOi K06173.
OrthoDBi EOG6Z9B4R.

Enzyme and pathway databases

BioCyci ZMOB622759:GI1C-590-MONOMER.

Family and domain databases

Gene3Di 3.30.70.580. 1 hit.
3.30.70.660. 1 hit.
HAMAPi MF_00171. TruA.
InterProi IPR020103. PsdUridine_synth_cat_dom.
IPR001406. PsdUridine_synth_TruA.
IPR020097. PsdUridine_synth_TruA_a/b_dom.
IPR020095. PsdUridine_synth_TruA_C.
IPR020094. PsdUridine_synth_TruA_N.
[Graphical view ]
PANTHERi PTHR11142. PTHR11142. 1 hit.
Pfami PF01416. PseudoU_synth_1. 2 hits.
[Graphical view ]
PIRSFi PIRSF001430. tRNA_psdUrid_synth. 1 hit.
SUPFAMi SSF55120. SSF55120. 1 hit.
TIGRFAMsi TIGR00071. hisT_truA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of the ethanol producer Zymomonas mobilis NCIMB 11163."
    Kouvelis V.N., Saunders E., Brettin T.S., Bruce D., Detter C., Han C., Typas M.A., Pappas K.M.
    J. Bacteriol. 191:7140-7141(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NCIB 11163Imported.

Entry informationi

Entry nameiC8WBE0_ZYMMN
AccessioniPrimary (citable) accession number: C8WBE0
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: November 26, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3