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C8WBE0

- C8WBE0_ZYMMN

UniProt

C8WBE0 - C8WBE0_ZYMMN

Protein

tRNA pseudouridine synthase A

Gene

truA

Organism
Zymomonas mobilis subsp. mobilis (strain NCIB 11163)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 34 (01 Oct 2014)
      Sequence version 1 (03 Nov 2009)
      Previous versions | rss
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    Functioni

    Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.UniRule annotationSAAS annotation

    Catalytic activityi

    tRNA uridine(38-40) = tRNA pseudouridine(38-40).UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei52 – 521NucleophileUniRule annotation
    Binding sitei111 – 1111SubstrateUniRule annotation

    GO - Molecular functioni

    1. pseudouridine synthase activity Source: UniProtKB-HAMAP
    2. RNA binding Source: InterPro

    GO - Biological processi

    1. tRNA pseudouridine synthesis Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    tRNA processingUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciZMOB622759:GI1C-590-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    tRNA pseudouridine synthase AUniRule annotation (EC:5.4.99.12UniRule annotation)
    Alternative name(s):
    tRNA pseudouridine(38-40) synthaseUniRule annotation
    tRNA pseudouridylate synthase IUniRule annotation
    tRNA-uridine isomerase IUniRule annotation
    Gene namesi
    Name:truAUniRule annotation
    Ordered Locus Names:Za10_0476Imported
    OrganismiZymomonas mobilis subsp. mobilis (strain NCIB 11163)Imported
    Taxonomic identifieri622759 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeZymomonas
    ProteomesiUP000000319: Chromosome

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi622759.Za10_0476.

    Structurei

    3D structure databases

    ProteinModelPortaliC8WBE0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the tRNA pseudouridine synthase TruA family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0101.
    HOGENOMiHOG000248672.
    KOiK06173.
    OrthoDBiEOG6Z9B4R.

    Family and domain databases

    Gene3Di3.30.70.580. 1 hit.
    3.30.70.660. 1 hit.
    HAMAPiMF_00171. TruA.
    InterProiIPR020103. PsdUridine_synth_cat_dom.
    IPR001406. PsdUridine_synth_TruA.
    IPR020097. PsdUridine_synth_TruA_a/b_dom.
    IPR020095. PsdUridine_synth_TruA_C.
    IPR020094. PsdUridine_synth_TruA_N.
    [Graphical view]
    PANTHERiPTHR11142. PTHR11142. 1 hit.
    PfamiPF01416. PseudoU_synth_1. 2 hits.
    [Graphical view]
    PIRSFiPIRSF001430. tRNA_psdUrid_synth. 1 hit.
    SUPFAMiSSF55120. SSF55120. 1 hit.
    TIGRFAMsiTIGR00071. hisT_truA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    C8WBE0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNRYRLTVEF DGRNFMGWQR QKHGATIQGS IEEAGASIAG QPTPVQAAGR    50
    TDAGVHGLAM TAHIDVARDF TPFRLMEALN ARLKPRPIAI LSCEQVDPEW 100
    HARFSCIGRR YLYRIINRRP PLTLEAGRAW HVIKPLDAET MDIAAKRLIG 150
    LHDFTTFRSV HCQSKSPVKT LDHLDVRRIG DQIEITAAAR SFLHHQVRSM 200
    VGCLVLVGQG QWTADDMTTA LEARNRAALG FNAPPDGLYF TQAIY 245
    Length:245
    Mass (Da):27,412
    Last modified:November 3, 2009 - v1
    Checksum:i6DE58C360928D760
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001722 Genomic DNA. Translation: ACV75026.1.
    RefSeqiYP_003225610.1. NC_013355.1.

    Genome annotation databases

    EnsemblBacteriaiACV75026; ACV75026; Za10_0476.
    GeneIDi8471570.
    KEGGizmn:Za10_0476.
    PATRICi24154002. VBIZymMob135463_0532.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001722 Genomic DNA. Translation: ACV75026.1 .
    RefSeqi YP_003225610.1. NC_013355.1.

    3D structure databases

    ProteinModelPortali C8WBE0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 622759.Za10_0476.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACV75026 ; ACV75026 ; Za10_0476 .
    GeneIDi 8471570.
    KEGGi zmn:Za10_0476.
    PATRICi 24154002. VBIZymMob135463_0532.

    Phylogenomic databases

    eggNOGi COG0101.
    HOGENOMi HOG000248672.
    KOi K06173.
    OrthoDBi EOG6Z9B4R.

    Enzyme and pathway databases

    BioCyci ZMOB622759:GI1C-590-MONOMER.

    Family and domain databases

    Gene3Di 3.30.70.580. 1 hit.
    3.30.70.660. 1 hit.
    HAMAPi MF_00171. TruA.
    InterProi IPR020103. PsdUridine_synth_cat_dom.
    IPR001406. PsdUridine_synth_TruA.
    IPR020097. PsdUridine_synth_TruA_a/b_dom.
    IPR020095. PsdUridine_synth_TruA_C.
    IPR020094. PsdUridine_synth_TruA_N.
    [Graphical view ]
    PANTHERi PTHR11142. PTHR11142. 1 hit.
    Pfami PF01416. PseudoU_synth_1. 2 hits.
    [Graphical view ]
    PIRSFi PIRSF001430. tRNA_psdUrid_synth. 1 hit.
    SUPFAMi SSF55120. SSF55120. 1 hit.
    TIGRFAMsi TIGR00071. hisT_truA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of the ethanol producer Zymomonas mobilis NCIMB 11163."
      Kouvelis V.N., Saunders E., Brettin T.S., Bruce D., Detter C., Han C., Typas M.A., Pappas K.M.
      J. Bacteriol. 191:7140-7141(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NCIB 11163Imported.

    Entry informationi

    Entry nameiC8WBE0_ZYMMN
    AccessioniPrimary (citable) accession number: C8WBE0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 3, 2009
    Last sequence update: November 3, 2009
    Last modified: October 1, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3