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C8W9G2

- C8W9G2_ATOPD

UniProt

C8W9G2 - C8W9G2_ATOPD

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Protein
Submitted name:

D-alanine--D-alanine ligase

Gene

Apar_0319

Organism
Atopobium parvulum (strain ATCC 33793 / DSM 20469 / JCM 10300 / VPI 0546) (Streptococcus parvulus) (Peptostreptococcus parvulus)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Cell wall formation.SAAS annotation

Catalytic activityi

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotation

Cofactori

Note: Binds 2 magnesium or manganese ions per subunit.SAAS annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. D-alanine-D-alanine ligase activity Source: UniProtKB-EC
  3. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. cell wall organization Source: UniProtKB-KW
  2. peptidoglycan biosynthetic process Source: UniProtKB-UniPathway
  3. regulation of cell shape Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseSAAS annotationImported

Keywords - Biological processi

Cell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, MagnesiumSAAS annotation, ManganeseSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciAPAR521095:GH57-329-MONOMER.
UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Submitted name:
D-alanine--D-alanine ligaseImported (EC:6.3.2.4Imported)
Gene namesi
Ordered Locus Names:Apar_0319Imported
OrganismiAtopobium parvulum (strain ATCC 33793 / DSM 20469 / JCM 10300 / VPI 0546) (Streptococcus parvulus) (Peptostreptococcus parvulus)Imported
Taxonomic identifieri521095 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCoriobacteridaeCoriobacterialesCoriobacterineaeCoriobacteriaceaeAtopobium
ProteomesiUP000000960: Chromosome

Subcellular locationi

Cytoplasm SAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi521095.Apar_0319.

Structurei

3D structure databases

ProteinModelPortaliC8W9G2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains ATP-grasp domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG1181.
HOGENOMiHOG000011592.
KOiK01921.
OMAiMGGASFE.
OrthoDBiEOG6ND0KB.

Family and domain databases

Gene3Di3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
InterProiIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERiPTHR23132. PTHR23132. 1 hit.
PfamiPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMiSSF52440. SSF52440. 1 hit.
PROSITEiPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C8W9G2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MATKVAVIMG GASFERNFSL KSGALVSEAL EKCGYEVLPL DADAHLVDTL
60 70 80 90 100
RAEKPDVAFV CLHGAGGEDG AVPALLEFLK IPYVGSRPAS CRAAWNKADM
110 120 130 140 150
PFIVRQAWSK EESEVIWPPQ IVLTASAFKD LGAAAALDMV PERLGGGVGF
160 170 180 190 200
PLAVKPVHGG SAMGLSKVDS ADQLGKALLG ALGFDDSVII QQWVDGVEVS
210 220 230 240 250
VTVLSDADGE KTLPPVEISV IKGIYDTDAR LDPERIEHFC PVRSESLAAL
260 270 280 290 300
GADPVAAREA LERAALEVFT AYGCRDLARI DFIWDGHHVM VMGLKTFPGL
310 320 330
TETSLVPMAI EAAGYAVEDV LAQLVEGALK RGN
Length:333
Mass (Da):35,252
Last modified:November 3, 2009 - v1
Checksum:i8F58F0D102398546
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001721 Genomic DNA. Translation: ACV50750.1.
RefSeqiWP_012808408.1. NC_013203.1.
YP_003179341.1. NC_013203.1.

Genome annotation databases

EnsemblBacteriaiACV50750; ACV50750; Apar_0319.
GeneIDi8413167.
KEGGiapv:Apar_0319.
PATRICi21006125. VBIAtoPar109073_0313.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001721 Genomic DNA. Translation: ACV50750.1 .
RefSeqi WP_012808408.1. NC_013203.1.
YP_003179341.1. NC_013203.1.

3D structure databases

ProteinModelPortali C8W9G2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 521095.Apar_0319.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACV50750 ; ACV50750 ; Apar_0319 .
GeneIDi 8413167.
KEGGi apv:Apar_0319.
PATRICi 21006125. VBIAtoPar109073_0313.

Phylogenomic databases

eggNOGi COG1181.
HOGENOMi HOG000011592.
KOi K01921.
OMAi MGGASFE.
OrthoDBi EOG6ND0KB.

Enzyme and pathway databases

UniPathwayi UPA00219 .
BioCyci APAR521095:GH57-329-MONOMER.

Family and domain databases

Gene3Di 3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
InterProi IPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view ]
PANTHERi PTHR23132. PTHR23132. 1 hit.
Pfami PF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view ]
SUPFAMi SSF52440. SSF52440. 1 hit.
PROSITEi PS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33793 / DSM 20469 / JCM 10300 / VPI 0546Imported.

Entry informationi

Entry nameiC8W9G2_ATOPD
AccessioniPrimary (citable) accession number: C8W9G2
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: November 26, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3