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C8W9G2

- C8W9G2_ATOPD

UniProt

C8W9G2 - C8W9G2_ATOPD

Protein
Submitted name:

D-alanine--D-alanine ligase

Gene

Apar_0319

Organism
Atopobium parvulum (strain ATCC 33793 / DSM 20469 / JCM 10300 / VPI 0546) (Streptococcus parvulus) (Peptostreptococcus parvulus)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 33 (01 Oct 2014)
      Sequence version 1 (03 Nov 2009)
      Previous versions | rss
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    Functioni

    Cell wall formation.SAAS annotation

    Catalytic activityi

    ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotation

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.SAAS annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. D-alanine-D-alanine ligase activity Source: UniProtKB-EC
    3. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. peptidoglycan biosynthetic process Source: UniProtKB-UniPathway
    2. regulation of cell shape Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseSAAS annotationImported

    Keywords - Biological processi

    Cell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation

    Keywords - Ligandi

    ATP-bindingSAAS annotation, MagnesiumSAAS annotation, ManganeseSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciAPAR521095:GH57-329-MONOMER.
    UniPathwayiUPA00219.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    D-alanine--D-alanine ligaseImported (EC:6.3.2.4Imported)
    Gene namesi
    Ordered Locus Names:Apar_0319Imported
    OrganismiAtopobium parvulum (strain ATCC 33793 / DSM 20469 / JCM 10300 / VPI 0546) (Streptococcus parvulus) (Peptostreptococcus parvulus)Imported
    Taxonomic identifieri521095 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaCoriobacteridaeCoriobacterialesCoriobacterineaeCoriobacteriaceaeAtopobium
    ProteomesiUP000000960: Chromosome

    Subcellular locationi

    Cytoplasm SAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmSAAS annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi521095.Apar_0319.

    Structurei

    3D structure databases

    ProteinModelPortaliC8W9G2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 ATP-grasp domain.
    Contains ATP-grasp domain.SAAS annotation

    Phylogenomic databases

    eggNOGiCOG1181.
    HOGENOMiHOG000011592.
    KOiK01921.
    OMAiMGGASFE.
    OrthoDBiEOG6ND0KB.

    Family and domain databases

    Gene3Di3.30.1490.20. 1 hit.
    3.30.470.20. 2 hits.
    3.40.50.20. 1 hit.
    InterProiIPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR000291. D-Ala_lig_Van_CS.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    IPR011127. Dala_Dala_lig_N.
    IPR016185. PreATP-grasp_dom.
    [Graphical view]
    PANTHERiPTHR23132. PTHR23132. 1 hit.
    PfamiPF07478. Dala_Dala_lig_C. 1 hit.
    PF01820. Dala_Dala_lig_N. 2 hits.
    [Graphical view]
    SUPFAMiSSF52440. SSF52440. 1 hit.
    PROSITEiPS50975. ATP_GRASP. 1 hit.
    PS00843. DALA_DALA_LIGASE_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C8W9G2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MATKVAVIMG GASFERNFSL KSGALVSEAL EKCGYEVLPL DADAHLVDTL    50
    RAEKPDVAFV CLHGAGGEDG AVPALLEFLK IPYVGSRPAS CRAAWNKADM 100
    PFIVRQAWSK EESEVIWPPQ IVLTASAFKD LGAAAALDMV PERLGGGVGF 150
    PLAVKPVHGG SAMGLSKVDS ADQLGKALLG ALGFDDSVII QQWVDGVEVS 200
    VTVLSDADGE KTLPPVEISV IKGIYDTDAR LDPERIEHFC PVRSESLAAL 250
    GADPVAAREA LERAALEVFT AYGCRDLARI DFIWDGHHVM VMGLKTFPGL 300
    TETSLVPMAI EAAGYAVEDV LAQLVEGALK RGN 333
    Length:333
    Mass (Da):35,252
    Last modified:November 3, 2009 - v1
    Checksum:i8F58F0D102398546
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001721 Genomic DNA. Translation: ACV50750.1.
    RefSeqiYP_003179341.1. NC_013203.1.

    Genome annotation databases

    EnsemblBacteriaiACV50750; ACV50750; Apar_0319.
    GeneIDi8413167.
    KEGGiapv:Apar_0319.
    PATRICi21006125. VBIAtoPar109073_0313.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001721 Genomic DNA. Translation: ACV50750.1 .
    RefSeqi YP_003179341.1. NC_013203.1.

    3D structure databases

    ProteinModelPortali C8W9G2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 521095.Apar_0319.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACV50750 ; ACV50750 ; Apar_0319 .
    GeneIDi 8413167.
    KEGGi apv:Apar_0319.
    PATRICi 21006125. VBIAtoPar109073_0313.

    Phylogenomic databases

    eggNOGi COG1181.
    HOGENOMi HOG000011592.
    KOi K01921.
    OMAi MGGASFE.
    OrthoDBi EOG6ND0KB.

    Enzyme and pathway databases

    UniPathwayi UPA00219 .
    BioCyci APAR521095:GH57-329-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1490.20. 1 hit.
    3.30.470.20. 2 hits.
    3.40.50.20. 1 hit.
    InterProi IPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR000291. D-Ala_lig_Van_CS.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    IPR011127. Dala_Dala_lig_N.
    IPR016185. PreATP-grasp_dom.
    [Graphical view ]
    PANTHERi PTHR23132. PTHR23132. 1 hit.
    Pfami PF07478. Dala_Dala_lig_C. 1 hit.
    PF01820. Dala_Dala_lig_N. 2 hits.
    [Graphical view ]
    SUPFAMi SSF52440. SSF52440. 1 hit.
    PROSITEi PS50975. ATP_GRASP. 1 hit.
    PS00843. DALA_DALA_LIGASE_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 33793 / DSM 20469 / JCM 10300 / VPI 0546Imported.

    Entry informationi

    Entry nameiC8W9G2_ATOPD
    AccessioniPrimary (citable) accession number: C8W9G2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 3, 2009
    Last sequence update: November 3, 2009
    Last modified: October 1, 2014
    This is version 33 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3