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C8W9G2

- C8W9G2_ATOPD

UniProt

C8W9G2 - C8W9G2_ATOPD

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Protein
Submitted name: D-alanine--D-alanine ligase
Gene
Apar_0319
Organism
Atopobium parvulum (strain ATCC 33793 / DSM 20469 / JCM 10300 / VPI 0546) (Streptococcus parvulus) (Peptostreptococcus parvulus)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Cell wall formation By similarity.SAAS annotations

Catalytic activityi

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotations

Cofactori

Binds 2 magnesium or manganese ions per subunit By similarity.SAAS annotations

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. D-alanine-D-alanine ligase activity Source: UniProtKB-EC
  3. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

  1. peptidoglycan biosynthetic process Source: UniProtKB-UniPathway
  2. regulation of cell shape Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseSAAS annotationsImported

Keywords - Biological processi

Cell shape, Cell wall biogenesis/degradationSAAS annotations, Peptidoglycan synthesisSAAS annotations

Keywords - Ligandi

ATP-bindingSAAS annotations, MagnesiumSAAS annotations, ManganeseSAAS annotations, Metal-bindingSAAS annotations, Nucleotide-binding

Enzyme and pathway databases

BioCyciAPAR521095:GH57-329-MONOMER.
UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Submitted name:
D-alanine--D-alanine ligaseImported (EC:6.3.2.4Imported)
Gene namesi
Ordered Locus Names:Apar_0319Imported
OrganismiAtopobium parvulum (strain ATCC 33793 / DSM 20469 / JCM 10300 / VPI 0546) (Streptococcus parvulus) (Peptostreptococcus parvulus)Imported
Taxonomic identifieri521095 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCoriobacteridaeCoriobacterialesCoriobacterineaeCoriobacteriaceaeAtopobium
ProteomesiUP000000960: Chromosome

Subcellular locationi

Cytoplasm By similarity SAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmSAAS annotations

Interactioni

Protein-protein interaction databases

STRINGi521095.Apar_0319.

Structurei

3D structure databases

ProteinModelPortaliC8W9G2.

Family & Domainsi

Sequence similaritiesi

Contains 1 ATP-grasp domain.
Contains ATP-grasp domain.SAAS annotations

Phylogenomic databases

eggNOGiCOG1181.
HOGENOMiHOG000011592.
KOiK01921.
OMAiMGGASFE.
OrthoDBiEOG6ND0KB.

Family and domain databases

Gene3Di3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
InterProiIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERiPTHR23132. PTHR23132. 1 hit.
PfamiPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMiSSF52440. SSF52440. 1 hit.
PROSITEiPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C8W9G2-1 [UniParc]FASTAAdd to Basket

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MATKVAVIMG GASFERNFSL KSGALVSEAL EKCGYEVLPL DADAHLVDTL    50
RAEKPDVAFV CLHGAGGEDG AVPALLEFLK IPYVGSRPAS CRAAWNKADM 100
PFIVRQAWSK EESEVIWPPQ IVLTASAFKD LGAAAALDMV PERLGGGVGF 150
PLAVKPVHGG SAMGLSKVDS ADQLGKALLG ALGFDDSVII QQWVDGVEVS 200
VTVLSDADGE KTLPPVEISV IKGIYDTDAR LDPERIEHFC PVRSESLAAL 250
GADPVAAREA LERAALEVFT AYGCRDLARI DFIWDGHHVM VMGLKTFPGL 300
TETSLVPMAI EAAGYAVEDV LAQLVEGALK RGN 333
Length:333
Mass (Da):35,252
Last modified:November 3, 2009 - v1
Checksum:i8F58F0D102398546
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001721 Genomic DNA. Translation: ACV50750.1.
RefSeqiYP_003179341.1. NC_013203.1.

Genome annotation databases

EnsemblBacteriaiACV50750; ACV50750; Apar_0319.
GeneIDi8413167.
KEGGiapv:Apar_0319.
PATRICi21006125. VBIAtoPar109073_0313.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001721 Genomic DNA. Translation: ACV50750.1 .
RefSeqi YP_003179341.1. NC_013203.1.

3D structure databases

ProteinModelPortali C8W9G2.
ModBasei Search...

Protein-protein interaction databases

STRINGi 521095.Apar_0319.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACV50750 ; ACV50750 ; Apar_0319 .
GeneIDi 8413167.
KEGGi apv:Apar_0319.
PATRICi 21006125. VBIAtoPar109073_0313.

Phylogenomic databases

eggNOGi COG1181.
HOGENOMi HOG000011592.
KOi K01921.
OMAi MGGASFE.
OrthoDBi EOG6ND0KB.

Enzyme and pathway databases

UniPathwayi UPA00219 .
BioCyci APAR521095:GH57-329-MONOMER.

Family and domain databases

Gene3Di 3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
InterProi IPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view ]
PANTHERi PTHR23132. PTHR23132. 1 hit.
Pfami PF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view ]
SUPFAMi SSF52440. SSF52440. 1 hit.
PROSITEi PS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33793 / DSM 20469 / JCM 10300 / VPI 0546.

Entry informationi

Entry nameiC8W9G2_ATOPD
AccessioniPrimary (citable) accession number: C8W9G2
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: May 14, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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