ID   C8W8H6_LANP1            Unreviewed;       394 AA.
AC   C8W8H6;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   27-MAR-2024, entry version 71.
DE   RecName: Full=protein-serine/threonine phosphatase {ECO:0000256|ARBA:ARBA00013081};
DE            EC=3.1.3.16 {ECO:0000256|ARBA:ARBA00013081};
GN   OrderedLocusNames=Apar_1343 {ECO:0000313|EMBL:ACV51767.1};
OS   Lancefieldella parvula (strain ATCC 33793 / DSM 20469 / CCUG 32760 / JCM
OS   10300 / KCTC 3663 / VPI 0546 / 1246) (Atopobium parvulum).
OC   Bacteria; Actinomycetota; Coriobacteriia; Coriobacteriales; Atopobiaceae;
OC   Lancefieldella.
OX   NCBI_TaxID=521095 {ECO:0000313|EMBL:ACV51767.1, ECO:0000313|Proteomes:UP000000960};
RN   [1] {ECO:0000313|EMBL:ACV51767.1, ECO:0000313|Proteomes:UP000000960}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33793 / DSM 20469 / CCUG 32760 / JCM 10300 / KCTC 3663 /
RC   VPI 0546 / 1246 {ECO:0000313|Proteomes:UP000000960};
RX   PubMed=21304653; DOI=10.4056/sigs.29547;
RA   Copeland A., Sikorski J., Lapidus A., Nolan M., Del Rio T.G., Lucas S.,
RA   Chen F., Tice H., Pitluck S., Cheng J.F., Pukall R., Chertkov O.,
RA   Brettin T., Han C., Detter J.C., Kuske C., Bruce D., Goodwin L.,
RA   Ivanova N., Mavromatis K., Mikhailova N., Chen A., Palaniappan K.,
RA   Chain P., Rohde M., Goker M., Bristow J., Eisen J.A., Markowitz V.,
RA   Hugenholtz P., Kyrpides N.C., Klenk H.P., Detter J.C.;
RT   "Complete genome sequence of Atopobium parvulum type strain (IPP 1246).";
RL   Stand. Genomic Sci. 1:166-173(2009).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] +
CC         phosphate; Xref=Rhea:RHEA:20629, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC         COMP:11604, ChEBI:CHEBI:15377, ChEBI:CHEBI:29999, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:83421; EC=3.1.3.16;
CC         Evidence={ECO:0000256|ARBA:ARBA00001512};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] +
CC         phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA-
CC         COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:61977; EC=3.1.3.16;
CC         Evidence={ECO:0000256|ARBA:ARBA00001482};
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DR   EMBL; CP001721; ACV51767.1; -; Genomic_DNA.
DR   AlphaFoldDB; C8W8H6; -.
DR   STRING; 521095.Apar_1343; -.
DR   KEGG; apv:Apar_1343; -.
DR   eggNOG; COG0631; Bacteria.
DR   HOGENOM; CLU_025431_2_1_11; -.
DR   Proteomes; UP000000960; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
DR   CDD; cd00143; PP2Cc; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR015050; BofC_C.
DR   InterPro; IPR015655; PP2C.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   NCBIfam; NF033484; Stp1_PP2C_phos; 1.
DR   PANTHER; PTHR47992:SF267; ALPHABET, ISOFORM E; 1.
DR   PANTHER; PTHR47992; PROTEIN PHOSPHATASE; 1.
DR   Pfam; PF08955; BofC_C; 1.
DR   Pfam; PF13672; PP2C_2; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SMART; SM00332; PP2Cc; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   PROSITE; PS51746; PPM_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000960};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        265..287
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          20..248
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS51746"
FT   REGION          362..394
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        374..394
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   394 AA;  41577 MW;  33032BA1DE5DED7F CRC64;
     MPLDGRGDTE AVSGSNTFIS WGARSDVGLV RDHNEDSFLL RTPLFAICDG MGGHAAGEVA
     SSIAVKVIAE QAPSTADDVR LGAAIEAANQ EVIDAPAKGV GKPGMGSTAS AVLIEGNQMA
     VAHVGDSRIY LLHHGTLVRI THDHSYVEEL IDSGQITADE ARTHPSRSVV TRALGSDPDM
     YADHFSLEVS DGDRIILCSD GLSGMVPDDE IESIAVSNVT PQKAADNLVS AALTYGGSDN
     ITVIVIDVLD DGIADQTRRH LTRGVIATFI SFLALFAATI AVFFLFVSSE WYLGINGTTV
     GVYRGIPTTI AGINMSSLVE TTSIEIKDLP DAVQDSLADG IRVKDEDEAH STVEDYRKQI
     DDANNRAVKK KEDAQSSGTP TTETTTSTTN SGGE
//