ID   C8W350_DESAS            Unreviewed;       705 AA.
AC   C8W350;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   27-MAR-2024, entry version 74.
DE   SubName: Full=Protein serine/threonine phosphatase {ECO:0000313|EMBL:ACV61817.1};
GN   OrderedLocusNames=Dtox_0924 {ECO:0000313|EMBL:ACV61817.1};
OS   Desulfofarcimen acetoxidans (strain ATCC 49208 / DSM 771 / KCTC 5769 / VKM
OS   B-1644 / 5575) (Desulfotomaculum acetoxidans).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Peptococcaceae;
OC   Desulfofarcimen.
OX   NCBI_TaxID=485916 {ECO:0000313|EMBL:ACV61817.1, ECO:0000313|Proteomes:UP000002217};
RN   [1] {ECO:0000313|EMBL:ACV61817.1, ECO:0000313|Proteomes:UP000002217}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49208 / DSM 771 / VKM B-1644
RC   {ECO:0000313|Proteomes:UP000002217};
RX   PubMed=21304664; DOI=10.4056/sigs.39508;
RA   Spring S., Lapidus A., Schroder M., Gleim D., Sims D., Meincke L.,
RA   Glavina Del Rio T., Tice H., Copeland A., Cheng J.F., Lucas S., Chen F.,
RA   Nolan M., Bruce D., Goodwin L., Pitluck S., Ivanova N., Mavromatis K.,
RA   Mikhailova N., Pati A., Chen A., Palaniappan K., Land M., Hauser L.,
RA   Chang Y.J., Jeffries C.D., Chain P., Saunders E., Brettin T., Detter J.C.,
RA   Goker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA   Kyrpides N.C., Klenk H.P., Han C.;
RT   "Complete genome sequence of Desulfotomaculum acetoxidans type strain
RT   (5575).";
RL   Stand. Genomic Sci. 1:242-253(2009).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; CP001720; ACV61817.1; -; Genomic_DNA.
DR   AlphaFoldDB; C8W350; -.
DR   STRING; 485916.Dtox_0924; -.
DR   KEGG; dae:Dtox_0924; -.
DR   eggNOG; COG2208; Bacteria.
DR   eggNOG; COG2770; Bacteria.
DR   HOGENOM; CLU_020306_1_0_9; -.
DR   OrthoDB; 9763484at2; -.
DR   Proteomes; UP000002217; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd18773; PDC1_HK_sensor; 1.
DR   CDD; cd12912; PDC2_MCP_like; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   InterPro; IPR029151; Sensor-like_sf.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF158472; HAMP domain-like; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   SUPFAM; SSF103190; Sensory domain-like; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS51746; PPM_2; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002217};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        14..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        365..385
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          389..441
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          481..695
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS51746"
FT   COILED          436..463
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   705 AA;  78553 MW;  A49712C83B4B1124 CRC64;
     MNQLVLKFGI RNKLLLLVLG ISLVSLLIFA YISYDAMKKL GNYAVESSAK LGTSAANDSQ
     NALEKQTGEY ILRVAKDQAD ISDKMLQHVK DNINEMAEYA AALWNNPNAF VSNPPLSLID
     AGTRVRVPYY LEVPGAIDPA AMKKELGLLG NMKYIFSPIL SNNLNISVVS IGTPSGITVL
     FSNSPPFDNK GFDPRVRPWY QKAMKQKDVI WTEPYEDAFG GGLMVTCAKA CYTKKGQFVG
     VVSADVTLNA LKEQIINTQI GNMGYALLMD EKGEFIVSPE TGLEHEKWNT SLINTVIERK
     TGVELNSFGY ENKYVAYAPV SSTNWILAVI MPQNEIIKPI VETKHKIAAS TRKSNEYITD
     SIKSVLTRFA VMLVIMLSII IFLAVRLSDK MVKPLLALSN GVKIVGGGNL EYNLAVHTKD
     EIEDLAAAFN KMTFDLNTYI KNLEETTAEK ERIESELKIA HAIQNSMLPR IFPPFPERKE
     INIFASMEPA KEVGGDFYDF FFIDQHKLCF VIADVSGKGV PAALFMVITK TLIKNHALLG
     LPADEIMTVV NDMLCEDNDE NMFVTAFLAI LDVHTGSLTF ANAGHNYPLL CRNGGEYDWL
     TSKKSFVLGG LENIEYQLNE LVLDQGDKLF IYTDGITEAM DDEERLYSEM RLQKTVNRLK
     DFAEAELVEG IKKDIREHVK GMSQSDDITM LVLRYNGCEN NATVL
//