Skip Header

Contribute Send feedback
Read comments (?) or add your own

C8W071 (C8W071_DESAS) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Methionyl-tRNA formyltransferase HAMAP-Rule MF_00182
EC=2.1.2.9 HAMAP-Rule MF_00182
Gene names
Name:fmt HAMAP-Rule MF_00182
Ordered Locus Names:Dtox_2313
OrganismDesulfotomaculum acetoxidans (strain ATCC 49208 / DSM 771 / VKM B-1644) [Complete proteome] [HAMAP] EMBL ACV63126.1
Taxonomic identifier485916 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Peptococcaceae › Desulfotomaculum ›

Protein attributes

Sequence length312 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP By similarity. HAMAP-Rule MF_00182 SAAS SAAS001555

Catalytic activity

10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = tetrahydrofolate + N-formylmethionyl-tRNA(fMet). HAMAP-Rule MF_00182 SAAS SAAS001555

Sequence similarities

Belongs to the fmt family. HAMAP-Rule MF_00182

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region109 – 1124Tetrahydrofolate (THF) binding By similarity HAMAP-Rule MF_00182

Sequences

Sequence LengthMass (Da)Tools
C8W071 [UniParc].

Last modified November 3, 2009. Version 1.
Checksum: 46DA37831138B477

FASTA31234,306
        10         20         30         40         50         60 
MKTVFMGSPD FAVPSLEKLY KMGFDIAGVV TQPDRPKGRG KKLLPTPVKI FAQSAGLKIF 

        70         80         90        100        110        120 
QPEKIKTPEF IRLLRNLSPQ VIVVVAFGQL LSPELLQIPQ FGCINVHASL LPKYRGAAPI 

       130        140        150        160        170        180 
HRAVINGEKV TGVTTMYMDE GLDTGDMILS QELPVEKQDT VGMVHDRLAV LGAEVLERTL 

       190        200        210        220        230        240 
QLVDDGEAPR QKQQDSSATY APLLTKADEI INWHSSAREI CNHIRGMNPW PGTCTYLDGQ 

       250        260        270        280        290        300 
VIKIWQATYG KRLVDAIGLP GQVMASDAGG IIIQAGQDQV CIKELQLQCC KRMMTADFLR 

       310 
GKQIPEGRCL GD

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001720 Genomic DNA. Translation: ACV63126.1.
RefSeqYP_003191749.1. NC_013216.1.

3D structure databases

ProteinModelPortalC8W071.
ModBaseSearch...

Protein-protein interaction databases

STRING485916.Dtox_2313.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACV63126; ACV63126; Dtox_2313.
GeneID8429297.
KEGGdae:Dtox_2313.
PATRIC21721485. VBIDesAce42372_2352.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0223.
HOGENOMHOG000261177.
KOK00604.
OMAGITLMQM.

Enzyme and pathway databases

BioCycDACE485916:GHUF-2378-MONOMER.

Family and domain databases

Gene3D3.10.25.10. 1 hit.
3.40.50.170. 1 hit.
HAMAPMF_00182. Formyl_trans.
InterProIPR005794. Fmt.
IPR005793. Formyl_trans_C.
IPR002376. Formyl_transf_N.
IPR011034. Formyl_transferase_C-like.
IPR001555. GART_AS.
IPR015518. Met_tRNA_Form_TA-like.
[Graphical view]
PANTHERPTHR11138. PTHR11138. 1 hit.
PfamPF02911. Formyl_trans_C. 1 hit.
PF00551. Formyl_trans_N. 1 hit.
[Graphical view]
SUPFAMSSF50486. FMT_C_like. 1 hit.
SSF53328. formyl_transf. 1 hit.
TIGRFAMsTIGR00460. fmt. 1 hit.
PROSITEPS00373. GART. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC8W071_DESAS
AccessionPrimary (citable) accession number: C8W071
Entry history
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: May 1, 2013
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info