C8VW47 (C8VW47_DESAS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Ribonuclease PH HAMAP-Rule MF_00564
Short name=RNase PH HAMAP-Rule MF_00564
EC=2.7.7.56 HAMAP-Rule MF_00564

Alternative name(s):
tRNA nucleotidyltransferase HAMAP-Rule MF_00564

Gene names

Name:	rph HAMAP-Rule MF_00564
Ordered Locus Names:	Dtox_3622

Organism

Desulfotomaculum acetoxidans (strain ATCC 49208 / DSM 771 / VKM B-1644) [Complete proteome] [HAMAP] EMBL ACV64334.1

Taxonomic identifier

485916 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Clostridia › Clostridiales › Peptococcaceae › Desulfotomaculum › Desulfotomaculum acetoxidans

Protein attributes

Sequence length	244 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates By similarity. HAMAP-Rule MF_00564 SAAS SAAS002381
Catalytic activity	tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate. HAMAP-Rule MF_00564 SAAS SAAS002381
Sequence similarities	Belongs to the RNase PH family. HAMAP-Rule MF_00564

Ontologies

Keywords
Biological process	tRNA processing HAMAP-Rule MF_00564 SAAS SAAS002381
Molecular function	Nucleotidyltransferase HAMAP-Rule MF_00564 SAAS SAAS002381 EMBL ACV64334.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tRNA processing Inferred from electronic annotation. Source: HAMAP
Molecular_function	tRNA binding Inferred from electronic annotation. Source: HAMAP tRNA nucleotidyltransferase activity Inferred from electronic annotation. Source: HAMAP tRNA-specific ribonuclease activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C8VW47 [UniParc]. Last modified November 3, 2009. Version 1. Checksum: 3E44300A21F95A25	FASTA	244	26,492
	10 20 30 40 50 60 MSRVDGRKPD EMRQVRMTRN FNKYAEGSVL IEVGDTHVLC TATVEDKVPP FLRGANKGWV 70 80 90 100 110 120 TAEYAMLPRA TDLRTGRERG KVSGRTMEIQ RLIGRALRSV VNLEALGERT VLVDCDVLQA 130 140 150 160 170 180 DGGTRTASIT GAFVAMTDAL YKLAVNGQIK KFPIKEFIAA TSVGRVNNEM VLDLCYKEDS 190 200 210 220 230 240 AAEVDMNIVM TGGDRFVEIQ GTGEEATFSR AEVNSLLDLA AGGIKSLIAF QSEVLGSIAK KVGV

References

[1]

"Complete genome sequence of Desulfotomaculum acetoxidans type strain (5575)." Spring S., Lapidus A., Schroder M., Gleim D., Sims D., Meincke L., Glavina Del Rio T., Tice H., Copeland A., Cheng J.F., Lucas S., Chen F., Nolan M., Bruce D., Goodwin L., Pitluck S., Ivanova N., Mavromatis K. , Mikhailova N., Pati A., Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D., Chain P., Saunders E., Brettin T., Detter J.C., Goker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P., Han C. Stand. Genomic Sci. 1:242-253(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49208 / DSM 771 / VKM B-1644.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001720 Genomic DNA. Translation: ACV64334.1.
RefSeq	YP_003192957.1. NC_013216.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	485916.Dtox_3622.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACV64334; ACV64334; Dtox_3622.
GeneID	8430630.
KEGG	dae:Dtox_3622.
PATRIC	21724199. VBIDesAce42372_3686.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0689.
HOGENOM	HOG000229516.
KO	K00989.
OMA	MLPRATG.
ProtClustDB	PRK00173.
Enzyme and pathway databases
BioCyc	DACE485916:GHUF-3711-MONOMER.
Family and domain databases
HAMAP	MF_00564. RNase_PH.
InterPro	IPR001247. ExoRNase_PH_dom1. IPR015847. ExoRNase_PH_dom2. IPR020568. Ribosomal_S5_D2-typ_fold. IPR002381. RNase_PH_bac-type. IPR018336. RNase_PH_CS. [Graphical view]
Pfam	PF01138. RNase_PH. 1 hit. PF03725. RNase_PH_C. 1 hit. [Graphical view]
SUPFAM	SSF55666. 3_ExoRNase. 1 hit. SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMs	TIGR01966. RNasePH. 1 hit.
PROSITE	PS01277. RIBONUCLEASE_PH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C8VW47_DESAS

Accession

Primary (citable) accession number: C8VW47

Entry history

Integrated into UniProtKB/TrEMBL:	November 3, 2009
Last sequence update:	November 3, 2009
Last modified:	May 1, 2013
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)