C8UIR8 (C8UIR8_ECO1A) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Copper transporter CopA EMBL BAI34496.1

Gene names

Name:	copA EMBL BAI34496.1
Ordered Locus Names:	ECO111_0519 EMBL BAI34496.1

Organism

Escherichia coli O111:H- (strain 11128 / EHEC) [Complete proteome] [HAMAP] EMBL BAI34496.1

Taxonomic identifier

585396 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli › Escherichia coli O111:H-

Protein attributes

Sequence length	834 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the cation transport ATPase (P-type) family. RuleBase RU000653

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane RuleBase RU000653
Ligand	ATP-binding RuleBase RU000653 Nucleotide-binding
Molecular function	Hydrolase RuleBase RU000653
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	metal ion transport Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cation-transporting ATPase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C8UIR8 [UniParc]. Last modified November 3, 2009. Version 1. Checksum: 1FDAE23F11466931	FASTA	834	87,937
	10 20 30 40 50 60 MSQIIDLTLD GLSCGHCVKR VKESLEQRPD VEQADVSITE AHVTGTASAE QLIETIKQAG 70 80 90 100 110 120 YDASVSHPKA KPLAESSIPS EALTAVSEAL PAATADDDDS QQLLLSGMSC ASCVTRVQNA 130 140 150 160 170 180 LQSVPGVTQA RVNLAERTAL VMGSASPQDL VQAVEKAGYG AEAIEDDAKR RERQQETAVA 190 200 210 220 230 240 TMKRFRWQAI VALAVGIPVM VWGMIGDNMM VTADNRSLWL VIGLITLAVM VFAGGHFYRS 250 260 270 280 290 300 AWKSLLNGAA TMDTLVALGT GVAWLYSMSV NLWPQWFPME ARHLYYEASA MIIGLINLGH 310 320 330 340 350 360 MLEARARQRS SKALEKLLDL TPPTARLVTD EGEKSVPLAE VQPGMLLRLT TGDRVPVDGE 370 380 390 400 410 420 ITQGEAWLDE AMLTGEPIPQ QKGEGESVHA GTVVQDGSVL FRASAVGSHT TLSRIIRMVR 430 440 450 460 470 480 QAQSSKPEIG QLADKISAVF VPVVVVIALV SAAIWYFFGP APQIVYTLVI ATTVLIIACP 490 500 510 520 530 540 CALGLATPMS IISGVGRAAE FGVLVRDADA LQRASTLDTV VFDKTGTLTE GKPQVVAVKT 550 560 570 580 590 600 FADVDEAQAL RLAAALEQGS SHPLARAILD KAGDMQLPQV NGFRTLRGLG VSGEAEGHAL 610 620 630 640 650 660 LLGNQALLNE QQVGTKAIEA EITAQASQGA TPVLLAVDGK AVALLAVRDP LRSDSVAALQ 670 680 690 700 710 720 RLHKAGYRLV MLTGDNPTTA NAIAKEAGID EVIAGVLPDG KAEAIKRLQS EGRQVAMVGD 730 740 750 760 770 780 GINDAPALAQ ADVGIAMGGG SDVAIETAAI TLMRHSLMGV ADALAISRAT LRNMKQNLLG 790 800 810 820 830 AFIYNSIGIP VAAGILWPFT GTLLNPVVAG AAMALSSITV VSNANRLLRF KPKE

References

[1]

"Comparative genomics reveal the mechanism of the parallel evolution of O157 and non-O157 enterohemorrhagic Escherichia coli." Ogura Y., Ooka T., Iguchi A., Toh H., Asadulghani M., Oshima K., Kodama T., Abe H., Nakayama K., Kurokawa K., Tobe T., Hattori M., Hayashi T. Proc. Natl. Acad. Sci. U.S.A. 106:17939-17944(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 11128 / EHEC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP010960 Genomic DNA. Translation: BAI34496.1.
RefSeq	YP_003233047.1. NC_013364.1.
3D structure databases
ProteinModelPortal	C8UIR8.
ModBase	Search...
Protein-protein interaction databases
STRING	585396.ECO111_0519.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAI34496; BAI34496; ECO111_0519.
GeneID	8488496.
KEGG	eoi:ECO111_0519.
PATRIC	32104096. VBIEscCol143187_0539.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2217.
HOGENOM	HOG000250397.
KO	K01533.
OMA	MHCATCV.
ProtClustDB	PRK10671.
Enzyme and pathway databases
BioCyc	ECOL585396:GJCW-531-MONOMER.
Family and domain databases
Gene3D	2.70.150.10. 1 hit. 3.40.1110.10. 1 hit. 3.40.50.1000. 2 hits.
InterPro	IPR023299. ATPase_P-typ_cyto_domN. IPR018303. ATPase_P-typ_P_site. IPR008250. ATPase_P-typ_transduc_dom_A. IPR027256. Cation_transp_P-typ_ATPase_IB. IPR001757. Cation_transp_P_typ_ATPase. IPR023214. HAD-like_dom. IPR017969. Heavy-metal-associated_CS. IPR006121. HeavyMe-assoc_HMA. [Graphical view]
PANTHER	PTHR24093. PTHR24093. 1 hit.
Pfam	PF00122. E1-E2_ATPase. 1 hit. PF00403. HMA. 2 hits. PF00702. Hydrolase. 1 hit. [Graphical view]
PRINTS	PR00119. CATATPASE. PR00120. HATPASE.
SUPFAM	SSF56784. HAD-like_dom. 1 hit. SSF55008. HeavyMe_transpt. 2 hits.
TIGRFAMs	TIGR01525. ATPase-IB_hvy. 1 hit. TIGR01494. ATPase_P-type. 1 hit.
PROSITE	PS00154. ATPASE_E1_E2. 1 hit. PS01047. HMA_1. 1 hit. PS50846. HMA_2. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C8UIR8_ECO1A

Accession

Primary (citable) accession number: C8UIR8

Entry history

Integrated into UniProtKB/TrEMBL:	November 3, 2009
Last sequence update:	November 3, 2009
Last modified:	May 1, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)