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Protein

Putative Holliday junction resolvase

Gene

yqgF

Organism
Escherichia coli O111:H- (strain 11128 / EHEC)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Could be a nuclease that resolves Holliday junction intermediates in genetic recombination.UniRule annotationSAAS annotation

GO - Molecular functioni

  1. nuclease activity Source: UniProtKB-KW
  2. nucleic acid binding Source: InterPro

GO - Biological processi

  1. DNA recombination Source: UniProtKB-HAMAP
  2. DNA repair Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, NucleaseUniRule annotationSAAS annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotationSAAS annotation, DNA repairUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciECOL585396:GJCW-3828-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative Holliday junction resolvaseUniRule annotationSAAS annotation (EC:3.1.-.-UniRule annotationSAAS annotation)
Gene namesi
Name:yqgFUniRule annotationImported
Ordered Locus Names:ECO111_3697Imported
OrganismiEscherichia coli O111:H- (strain 11128 / EHEC)Imported
Taxonomic identifieri585396 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000001614: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi585396.ECO111_3697.

Structurei

3D structure databases

ProteinModelPortaliC8UFG5.
SMRiC8UFG5. Positions 1-138.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the YqgF HJR family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0816.
HOGENOMiHOG000016954.
KOiK07447.
OMAiPMGWTAQ.
OrthoDBiEOG6N94FV.

Family and domain databases

Gene3Di3.30.420.140. 1 hit.
HAMAPiMF_00651. HJR_YqgF.
InterProiIPR005227. Resolv_Hlld_junc_YqgF-like.
IPR012337. RNaseH-like_dom.
IPR006641. YqgF/RNaseH-like_dom.
[Graphical view]
PfamiPF03652. UPF0081. 1 hit.
[Graphical view]
SMARTiSM00732. YqgFc. 1 hit.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 1 hit.
TIGRFAMsiTIGR00250. RNAse_H_YqgF. 1 hit.

Sequencei

Sequence statusi: Complete.

C8UFG5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGTLLAFDF GTKSIGVAVG QRITGTARPL PAIKAQDGTP DWNLIERLLK
60 70 80 90 100
EWQPDEIIVG LPLNMDGTEQ PLTARARKFA NRIHGRFGVE VKLHDERLST
110 120 130
VEARSGLFEQ GGYRALNKGK VDSASAVIIL ESYFEQGY
Length:138
Mass (Da):15,186
Last modified:November 3, 2009 - v1
Checksum:i8E627612AA2C1B05
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP010960 Genomic DNA. Translation: BAI37487.1.
RefSeqiYP_003236038.1. NC_013364.1.

Genome annotation databases

EnsemblBacteriaiBAI37487; BAI37487; ECO111_3697.
GeneIDi8489731.
KEGGieoi:ECO111_3697.
PATRICi32110818. VBIEscCol143187_3823.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP010960 Genomic DNA. Translation: BAI37487.1.
RefSeqiYP_003236038.1. NC_013364.1.

3D structure databases

ProteinModelPortaliC8UFG5.
SMRiC8UFG5. Positions 1-138.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi585396.ECO111_3697.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAI37487; BAI37487; ECO111_3697.
GeneIDi8489731.
KEGGieoi:ECO111_3697.
PATRICi32110818. VBIEscCol143187_3823.

Phylogenomic databases

eggNOGiCOG0816.
HOGENOMiHOG000016954.
KOiK07447.
OMAiPMGWTAQ.
OrthoDBiEOG6N94FV.

Enzyme and pathway databases

BioCyciECOL585396:GJCW-3828-MONOMER.

Family and domain databases

Gene3Di3.30.420.140. 1 hit.
HAMAPiMF_00651. HJR_YqgF.
InterProiIPR005227. Resolv_Hlld_junc_YqgF-like.
IPR012337. RNaseH-like_dom.
IPR006641. YqgF/RNaseH-like_dom.
[Graphical view]
PfamiPF03652. UPF0081. 1 hit.
[Graphical view]
SMARTiSM00732. YqgFc. 1 hit.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 1 hit.
TIGRFAMsiTIGR00250. RNAse_H_YqgF. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Comparative genomics reveal the mechanism of the parallel evolution of O157 and non-O157 enterohemorrhagic Escherichia coli."
    Ogura Y., Ooka T., Iguchi A., Toh H., Asadulghani M., Oshima K., Kodama T., Abe H., Nakayama K., Kurokawa K., Tobe T., Hattori M., Hayashi T.
    Proc. Natl. Acad. Sci. U.S.A. 106:17939-17944(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 11128 / EHECImported.

Entry informationi

Entry nameiC8UFG5_ECO1A
AccessioniPrimary (citable) accession number: C8UFG5
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: March 4, 2015
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.