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C8UAU3 (C8UAU3_ECO10) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Agmatinase HAMAP MF_01418
EC=3.5.3.11 HAMAP MF_01418
Alternative name(s):
Agmatine ureohydrolase HAMAP MF_01418
Gene names
Name:speB HAMAP MF_01418 EMBL BAI32251.1
Ordered Locus Names:ECO103_3517
OrganismEscherichia coli O103:H2 (strain 12009 / EHEC) [Complete proteome] [HAMAP]
Taxonomic identifier585395 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length306 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of putrescine from agmatine By similarity. SAAS SAAS023696 HAMAP MF_01418

Catalytic activity

Agmatine + H2O = putrescine + urea. HAMAP MF_01418 SAAS SAAS023696

Cofactor

Manganese By similarity. SAAS SAAS023696 HAMAP MF_01418

Pathway

Amine and polyamine biosynthesis; putrescine biosynthesis via agmatine pathway; putrescine from agmatine: step 1/1. HAMAP MF_01418

Sequence similarities

Belongs to the arginase family. Agmatinase subfamily. HAMAP MF_01418

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding1261Manganese By similarity HAMAP MF_01418
Metal binding1491Manganese By similarity HAMAP MF_01418
Metal binding1511Manganese By similarity HAMAP MF_01418
Metal binding1531Manganese By similarity HAMAP MF_01418
Metal binding2301Manganese By similarity HAMAP MF_01418
Metal binding2321Manganese By similarity HAMAP MF_01418

Sequences

Sequence LengthMass (Da)Tools
C8UAU3 [UniParc].

Last modified November 3, 2009. Version 1.
Checksum: 48208BF2CF155570

FASTA30633,557
        10         20         30         40         50         60 
MSTLGHQYDN SLVSNAFGFL RLPMNFQPYD SDADWVITGV PFDMATSGRA GGRHGPAAIR 

        70         80         90        100        110        120 
QVSTNLAWEH NRFPWNFDMR ERLNVVDCGD LVYAFGDARE MSEKLQAHAE KLLAAGKRML 

       130        140        150        160        170        180 
SFGGDHFVTL PLLRAHAKHF GKMALVHFDA HTDTYANGCE FDHGTMFYTA PKEGLIDPNH 

       190        200        210        220        230        240 
SVQIGIRTEF DKDNGFTVLD ACQVNDRSVD DVIAQVKQIV GDMPVYLTFD IDCLDPAFAP 

       250        260        270        280        290        300 
GTGTPVIGGL TSDRAIKLVR GLKDLNIVGM DVVEVAPAYD QSEITALAAA TLALEMLYIQ 


AAKKGE

« Hide

References

[1]"Comparative genomics reveal the mechanism of the parallel evolution of O157 and non-O157 enterohemorrhagic Escherichia coli."
Ogura Y., Ooka T., Iguchi A., Toh H., Asadulghani M., Oshima K., Kodama T., Abe H., Nakayama K., Kurokawa K., Tobe T., Hattori M., Hayashi T.
Proc. Natl. Acad. Sci. U.S.A. 106:17939-17944(2009) [PubMed: 19815525] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 12009 EMBL BAI32251.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP010958 Genomic DNA. Translation: BAI32251.1.
RefSeqYP_003223385.1. NC_013353.1.

3D structure databases

ProteinModelPortalC8UAU3.
SMRC8UAU3. Positions 12-304.
ModBaseSearch...

Protein-protein interaction databases

STRINGC8UAU3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBESCT00000176871; EBESCP00000169389; EBESCG00000178603.
GeneID8474141.
GenomeReviewsGene locus ECO103_3517 in contig AP010958_GR.
KEGGeoh:ECO103_3517.
PATRIC32099037. VBIEscCol146794_3676.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000009564.
OMAIRTEYDH.
ProtClustDBPRK02190.

Family and domain databases

HAMAPMF_01418. SpeB.
[Tree]
InterProIPR023694. Agmatinase.
IPR005925. Agmatinase-rel.
IPR006035. Ureohydrolase.
IPR023696. Ureohydrolase_domain.
IPR020855. Ureohydrolase_Mn_BS.
[Graphical view]
Gene3DG3DSA:3.40.800.10. Ureohydrolase. 1 hit.
KOK01480.
PANTHERPTHR11358. Ureohydrolase. 1 hit.
PfamPF00491. Arginase. 1 hit.
[Graphical view]
PIRSFPIRSF036979. Arginase. 1 hit.
TIGRFAMsTIGR01230. Agmatinase. 1 hit.
PROSITEPS01053. ARGINASE_1. 1 hit.
PS51409. ARGINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC8UAU3_ECO10
AccessionPrimary (citable) accession number: C8UAU3
Entry history
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: December 14, 2011
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info