C8U995 (C8U995_ECO10) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
4-aminobutyrate aminotransferase, PLP-dependent EMBL BAI31954.1

Gene names

Name:	gabT EMBL BAI31954.1
Ordered Locus Names:	ECO103_3203 EMBL BAI31954.1

Organism

Escherichia coli O103:H2 (strain 12009 / EHEC) [Complete proteome] [HAMAP] EMBL BAI31954.1

Taxonomic identifier

585395 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli › Escherichia coli O103:H2

Protein attributes

Sequence length	426 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. RuleBase RU003560

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU003560
Molecular function	Aminotransferase EMBL BAI31954.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	gamma-aminobutyric acid metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	4-aminobutyrate transaminase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C8U995 [UniParc]. Last modified November 3, 2009. Version 1. Checksum: 625875AD3268CB7F	FASTA	426	45,747
	10 20 30 40 50 60 MSSNKELMQR RSQAIPRGVG QIHPIFADRA ENCRVWDVEG REYLDFAGGI AVLNTGHLHP 70 80 90 100 110 120 KVVAAVEAQL KKLSHTCFQV LAYEPYLELC EIMNQKVPGN FAKKTLLVTT GSEAVENAVK 130 140 150 160 170 180 IARAATKRSG TIAFSGAYHG RTHYTLALTG KVNPYSAGMG LMPGHVYRAL YPCPLHGISE 190 200 210 220 230 240 DDAIASIHRI FKNDAAPEDI AAIVIEPVQG EGGFYASSPA FMQRLRALCD EHGIMLIADE 250 260 270 280 290 300 VQSGAGRTGT LFAMEQMGVA PDLTTFAKSI AGGFPLAGVT GRAEVMDAVA PGGLGGTYAG 310 320 330 340 350 360 NPIACVAALE VLKVFEQENL LQKANDLGQK LKDGLLAIAE KHPEIGDVRG LGAMIAIELF 370 380 390 400 410 420 EDGDHNKPDA KLTAEIVARA RDKGLILLSC GPYYNVLRIL VPLTIEDAQI RQGLEIISQC FDEAKQ

References

[1]

"Comparative genomics reveal the mechanism of the parallel evolution of O157 and non-O157 enterohemorrhagic Escherichia coli." Ogura Y., Ooka T., Iguchi A., Toh H., Asadulghani M., Oshima K., Kodama T., Abe H., Nakayama K., Kurokawa K., Tobe T., Hattori M., Hayashi T. Proc. Natl. Acad. Sci. U.S.A. 106:17939-17944(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 12009 / EHEC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP010958 Genomic DNA. Translation: BAI31954.1.
RefSeq	YP_003223088.1. NC_013353.1.
3D structure databases
ProteinModelPortal	C8U995.
SMR	C8U995. Positions 2-426.
ModBase	Search...
Protein-protein interaction databases
STRING	585395.ECO103_3203.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAI31954; BAI31954; ECO103_3203.
GeneID	8475405.
KEGG	eoh:ECO103_3203.
PATRIC	32098359. VBIEscCol146794_3346.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0160.
HOGENOM	HOG000020206.
KO	K07250.
OMA	NLCAEAN.
ProtClustDB	PRK08088.
Enzyme and pathway databases
BioCyc	ECOL585395:GJA9-3311-MONOMER.
Family and domain databases
Gene3D	3.40.640.10. 1 hit. 3.90.1150.10. 1 hit.
InterPro	IPR004632. 4NH2But_aminotransferase_bac. IPR005814. Aminotrans_3. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
PANTHER	PTHR11986. PTHR11986. 1 hit.
Pfam	PF00202. Aminotran_3. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR00700. GABAtrnsam. 1 hit.
PROSITE	PS00600. AA_TRANSFER_CLASS_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C8U995_ECO10

Accession

Primary (citable) accession number: C8U995

Entry history

Integrated into UniProtKB/TrEMBL:	November 3, 2009
Last sequence update:	November 3, 2009
Last modified:	May 1, 2013
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)