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C8U864

- C8U864_ECO10

UniProt

C8U864 - C8U864_ECO10

Protein
Submitted name:

Fermentative D-lactate dehydrogenase, NAD-dependent

Gene

ldhA

Organism
Escherichia coli O103:H2 (strain 12009 / EHEC)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
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    • History
      Entry version 37 (01 Oct 2014)
      Sequence version 1 (03 Nov 2009)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. NAD binding Source: InterPro
    2. oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotation

    Enzyme and pathway databases

    BioCyciECOL585395:GJA9-1561-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Fermentative D-lactate dehydrogenase, NAD-dependentImported
    Gene namesi
    Name:ldhAImported
    Ordered Locus Names:ECO103_1516Imported
    OrganismiEscherichia coli O103:H2 (strain 12009 / EHEC)Imported
    Taxonomic identifieri585395 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000000959: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi585395.ECO103_1516.

    Structurei

    3D structure databases

    ProteinModelPortaliC8U864.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1052.
    HOGENOMiHOG000136695.
    KOiK03778.
    OMAiFNMHGRT.
    OrthoDBiEOG61VZ8G.

    Family and domain databases

    Gene3Di3.40.50.720. 2 hits.
    InterProiIPR006139. D-isomer_2_OHA_DH_cat_dom.
    IPR006140. D-isomer_DH_NAD-bd.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PfamiPF00389. 2-Hacid_dh. 1 hit.
    PF02826. 2-Hacid_dh_C. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C8U864-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKLAVYSTKQ YDKKYLQQVN ESFGFELEFF DFLLTEKTAK TANGCEAVCI    50
    FVNDDGSRPV LEELKKHGVK YIALRCAGFN NVDLDAAKEL GLKVVRVPAY 100
    DPEAVAEHAI GMMMTLNRRI HRAYQRTRDA NFSLEGLTGF TMYGKTAGVI 150
    GTGKIGVAML RILKGFGMRL LAFDPYPSAA ALELGVEYVD LPTLFSESDV 200
    ISLHCPLTPE NYHLLNEAAF DQMKNGVMIV NTSRGALIDS QAAIEALKNQ 250
    KIGSLGMDVY ENERDLFFED KSNDVIQDDV FRRLSACHNV LFTGHQAFLT 300
    AEALTSISQT TLQNLSNLEK GETCPNELV 329
    Length:329
    Mass (Da):36,521
    Last modified:November 3, 2009 - v1
    Checksum:i84E8F685F913993C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP010958 Genomic DNA. Translation: BAI30342.1.
    RefSeqiYP_003221476.1. NC_013353.1.

    Genome annotation databases

    EnsemblBacteriaiBAI30342; BAI30342; ECO103_1516.
    GeneIDi8475663.
    KEGGieoh:ECO103_1516.
    PATRICi32094779. VBIEscCol146794_1591.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP010958 Genomic DNA. Translation: BAI30342.1 .
    RefSeqi YP_003221476.1. NC_013353.1.

    3D structure databases

    ProteinModelPortali C8U864.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 585395.ECO103_1516.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAI30342 ; BAI30342 ; ECO103_1516 .
    GeneIDi 8475663.
    KEGGi eoh:ECO103_1516.
    PATRICi 32094779. VBIEscCol146794_1591.

    Phylogenomic databases

    eggNOGi COG1052.
    HOGENOMi HOG000136695.
    KOi K03778.
    OMAi FNMHGRT.
    OrthoDBi EOG61VZ8G.

    Enzyme and pathway databases

    BioCyci ECOL585395:GJA9-1561-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.720. 2 hits.
    InterProi IPR006139. D-isomer_2_OHA_DH_cat_dom.
    IPR006140. D-isomer_DH_NAD-bd.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    Pfami PF00389. 2-Hacid_dh. 1 hit.
    PF02826. 2-Hacid_dh_C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Comparative genomics reveal the mechanism of the parallel evolution of O157 and non-O157 enterohemorrhagic Escherichia coli."
      Ogura Y., Ooka T., Iguchi A., Toh H., Asadulghani M., Oshima K., Kodama T., Abe H., Nakayama K., Kurokawa K., Tobe T., Hattori M., Hayashi T.
      Proc. Natl. Acad. Sci. U.S.A. 106:17939-17944(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 12009 / EHECImported.

    Entry informationi

    Entry nameiC8U864_ECO10
    AccessioniPrimary (citable) accession number: C8U864
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 3, 2009
    Last sequence update: November 3, 2009
    Last modified: October 1, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3