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C8U864

- C8U864_ECO10

UniProt

C8U864 - C8U864_ECO10

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Protein
Submitted name:

Fermentative D-lactate dehydrogenase, NAD-dependent

Gene

ldhA

Organism
Escherichia coli O103:H2 (strain 12009 / EHEC)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. NAD binding Source: InterPro
  2. oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Enzyme and pathway databases

BioCyciECOL585395:GJA9-1561-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Fermentative D-lactate dehydrogenase, NAD-dependentImported
Gene namesi
Name:ldhAImported
Ordered Locus Names:ECO103_1516Imported
OrganismiEscherichia coli O103:H2 (strain 12009 / EHEC)Imported
Taxonomic identifieri585395 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000959: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi585395.ECO103_1516.

Structurei

3D structure databases

ProteinModelPortaliC8U864.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1052.
HOGENOMiHOG000136695.
KOiK03778.
OMAiFNMHGRT.
OrthoDBiEOG61VZ8G.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR006139. D-isomer_2_OHA_DH_cat_dom.
IPR029753. D-isomer_DH_CS.
IPR029752. D-isomer_DH_CS1.
IPR006140. D-isomer_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00389. 2-Hacid_dh. 1 hit.
PF02826. 2-Hacid_dh_C. 1 hit.
[Graphical view]
PROSITEiPS00065. D_2_HYDROXYACID_DH_1. 1 hit.
PS00670. D_2_HYDROXYACID_DH_2. 1 hit.
PS00671. D_2_HYDROXYACID_DH_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C8U864-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKLAVYSTKQ YDKKYLQQVN ESFGFELEFF DFLLTEKTAK TANGCEAVCI
60 70 80 90 100
FVNDDGSRPV LEELKKHGVK YIALRCAGFN NVDLDAAKEL GLKVVRVPAY
110 120 130 140 150
DPEAVAEHAI GMMMTLNRRI HRAYQRTRDA NFSLEGLTGF TMYGKTAGVI
160 170 180 190 200
GTGKIGVAML RILKGFGMRL LAFDPYPSAA ALELGVEYVD LPTLFSESDV
210 220 230 240 250
ISLHCPLTPE NYHLLNEAAF DQMKNGVMIV NTSRGALIDS QAAIEALKNQ
260 270 280 290 300
KIGSLGMDVY ENERDLFFED KSNDVIQDDV FRRLSACHNV LFTGHQAFLT
310 320
AEALTSISQT TLQNLSNLEK GETCPNELV
Length:329
Mass (Da):36,521
Last modified:November 3, 2009 - v1
Checksum:i84E8F685F913993C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP010958 Genomic DNA. Translation: BAI30342.1.
RefSeqiYP_003221476.1. NC_013353.1.

Genome annotation databases

EnsemblBacteriaiBAI30342; BAI30342; ECO103_1516.
GeneIDi8475663.
KEGGieoh:ECO103_1516.
PATRICi32094779. VBIEscCol146794_1591.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP010958 Genomic DNA. Translation: BAI30342.1 .
RefSeqi YP_003221476.1. NC_013353.1.

3D structure databases

ProteinModelPortali C8U864.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 585395.ECO103_1516.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAI30342 ; BAI30342 ; ECO103_1516 .
GeneIDi 8475663.
KEGGi eoh:ECO103_1516.
PATRICi 32094779. VBIEscCol146794_1591.

Phylogenomic databases

eggNOGi COG1052.
HOGENOMi HOG000136695.
KOi K03778.
OMAi FNMHGRT.
OrthoDBi EOG61VZ8G.

Enzyme and pathway databases

BioCyci ECOL585395:GJA9-1561-MONOMER.

Family and domain databases

Gene3Di 3.40.50.720. 2 hits.
InterProi IPR006139. D-isomer_2_OHA_DH_cat_dom.
IPR029753. D-isomer_DH_CS.
IPR029752. D-isomer_DH_CS1.
IPR006140. D-isomer_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
Pfami PF00389. 2-Hacid_dh. 1 hit.
PF02826. 2-Hacid_dh_C. 1 hit.
[Graphical view ]
PROSITEi PS00065. D_2_HYDROXYACID_DH_1. 1 hit.
PS00670. D_2_HYDROXYACID_DH_2. 1 hit.
PS00671. D_2_HYDROXYACID_DH_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Comparative genomics reveal the mechanism of the parallel evolution of O157 and non-O157 enterohemorrhagic Escherichia coli."
    Ogura Y., Ooka T., Iguchi A., Toh H., Asadulghani M., Oshima K., Kodama T., Abe H., Nakayama K., Kurokawa K., Tobe T., Hattori M., Hayashi T.
    Proc. Natl. Acad. Sci. U.S.A. 106:17939-17944(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 12009 / EHECImported.

Entry informationi

Entry nameiC8U864_ECO10
AccessioniPrimary (citable) accession number: C8U864
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: October 29, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3