C8U864 (C8U864_ECO10) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Fermentative D-lactate dehydrogenase, NAD-dependent EMBL BAI30342.1

Gene names

Name:	ldhA EMBL BAI30342.1
Ordered Locus Names:	ECO103_1516 EMBL BAI30342.1

Organism

Escherichia coli O103:H2 (strain 12009 / EHEC) [Complete proteome] [HAMAP] EMBL BAI30342.1

Taxonomic identifier

585395 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli › Escherichia coli O103:H2

Protein attributes

Sequence length	329 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. RuleBase RU003719

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU003720
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	NAD binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C8U864 [UniParc]. Last modified November 3, 2009. Version 1. Checksum: 84E8F685F913993C	FASTA	329	36,521
	10 20 30 40 50 60 MKLAVYSTKQ YDKKYLQQVN ESFGFELEFF DFLLTEKTAK TANGCEAVCI FVNDDGSRPV 70 80 90 100 110 120 LEELKKHGVK YIALRCAGFN NVDLDAAKEL GLKVVRVPAY DPEAVAEHAI GMMMTLNRRI 130 140 150 160 170 180 HRAYQRTRDA NFSLEGLTGF TMYGKTAGVI GTGKIGVAML RILKGFGMRL LAFDPYPSAA 190 200 210 220 230 240 ALELGVEYVD LPTLFSESDV ISLHCPLTPE NYHLLNEAAF DQMKNGVMIV NTSRGALIDS 250 260 270 280 290 300 QAAIEALKNQ KIGSLGMDVY ENERDLFFED KSNDVIQDDV FRRLSACHNV LFTGHQAFLT 310 320 AEALTSISQT TLQNLSNLEK GETCPNELV

References

[1]

"Comparative genomics reveal the mechanism of the parallel evolution of O157 and non-O157 enterohemorrhagic Escherichia coli." Ogura Y., Ooka T., Iguchi A., Toh H., Asadulghani M., Oshima K., Kodama T., Abe H., Nakayama K., Kurokawa K., Tobe T., Hattori M., Hayashi T. Proc. Natl. Acad. Sci. U.S.A. 106:17939-17944(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 12009 / EHEC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP010958 Genomic DNA. Translation: BAI30342.1.
RefSeq	YP_003221476.1. NC_013353.1.
3D structure databases
ProteinModelPortal	C8U864.
ModBase	Search...
Protein-protein interaction databases
STRING	585395.ECO103_1516.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAI30342; BAI30342; ECO103_1516.
GeneID	8475663.
KEGG	eoh:ECO103_1516.
PATRIC	32094779. VBIEscCol146794_1591.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1052.
HOGENOM	HOG000136695.
KO	K03778.
OMA	QQFGYEL.
ProtClustDB	CLSK869554.
Enzyme and pathway databases
BioCyc	ECOL585395:GJA9-1561-MONOMER.
Family and domain databases
Gene3D	3.40.50.720. 2 hits.
InterPro	IPR006139. D-isomer_2_OHA_DH_cat_dom. IPR006140. D-isomer_2_OHA_DH_NAD-bd. IPR016040. NAD(P)-bd_dom. [Graphical view]
Pfam	PF00389. 2-Hacid_dh. 1 hit. PF02826. 2-Hacid_dh_C. 1 hit. [Graphical view]
PROSITE	PS00065. D_2_HYDROXYACID_DH_1. 1 hit. PS00670. D_2_HYDROXYACID_DH_2. 1 hit. PS00671. D_2_HYDROXYACID_DH_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C8U864_ECO10

Accession

Primary (citable) accession number: C8U864

Entry history

Integrated into UniProtKB/TrEMBL:	November 3, 2009
Last sequence update:	November 3, 2009
Last modified:	May 1, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)