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C8U6W6 (C8U6W6_ECO10) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptidyl-tRNA hydrolase HAMAP-Rule MF_00083
Short name=PTH HAMAP-Rule MF_00083
EC=3.1.1.29 HAMAP-Rule MF_00083
Gene names
Name:pth HAMAP-Rule MF_00083 EMBL BAI30140.1
Ordered Locus Names:ECO103_1306 EMBL BAI30140.1
OrganismEscherichia coli O103:H2 (strain 12009 / EHEC) [Complete proteome] [HAMAP] EMBL BAI30140.1
Taxonomic identifier585395 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia ›

Protein attributes

Sequence length194 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis By similarity. HAMAP-Rule MF_00083

Catalytic activity

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA. HAMAP-Rule MF_00083 RuleBase RU000673

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00083

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00083.

Sequence similarities

Belongs to the PTH family. HAMAP-Rule MF_00083 RuleBase RU004320

Ontologies

Keywords
   Cellular componentCytoplasm HAMAP-Rule MF_00083
   Molecular functionHydrolase HAMAP-Rule MF_00083 RuleBase RU000673 EMBL BAI30140.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtranslation

Inferred from electronic annotation. Source: HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionaminoacyl-tRNA hydrolase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
C8U6W6 [UniParc].

Last modified November 3, 2009. Version 1.
Checksum: A28A69A63F2DD530

FASTA19421,082
        10         20         30         40         50         60 
MTIKLIVGLA NPGAEYAATR HNAGAWFVDL LAERLRAPLR EEAKFFGYTS RVTLGGEDVR 

        70         80         90        100        110        120 
LLVPTTFMNL SGKAVAAMAS FFRINPDEIL VAHDELDLPP GVAKFKLGGG HGGHNGLKDI 

       130        140        150        160        170        180 
ISKLGNNPNF HRLRIGIGHP GDKNKVVGFV LGKPPVSEQK LIDEAIDEAA RCTEMWFTDG 

       190 
LTKATNRLHA FKAQ

« Hide

References

[1]"Comparative genomics reveal the mechanism of the parallel evolution of O157 and non-O157 enterohemorrhagic Escherichia coli."
Ogura Y., Ooka T., Iguchi A., Toh H., Asadulghani M., Oshima K., Kodama T., Abe H., Nakayama K., Kurokawa K., Tobe T., Hattori M., Hayashi T.
Proc. Natl. Acad. Sci. U.S.A. 106:17939-17944(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 12009 / EHEC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP010958 Genomic DNA. Translation: BAI30140.1.
RefSeqYP_003221274.1. NC_013353.1.

3D structure databases

ProteinModelPortalC8U6W6.
SMRC8U6W6. Positions 2-194.
ModBaseSearch...

Protein-protein interaction databases

STRING585395.ECO103_1306.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAI30140; BAI30140; ECO103_1306.
GeneID8477459.
KEGGeoh:ECO103_1306.
PATRIC32094340. VBIEscCol146794_1374.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0193.
HOGENOMHOG000004796.
KOK01056.
OMAIKFKTGG.
ProtClustDBPRK05426.

Enzyme and pathway databases

BioCycECOL585395:GJA9-1343-MONOMER.

Family and domain databases

Gene3D3.40.50.1470. 1 hit.
HAMAPMF_00083. Pept_tRNA_hydro_bact.
InterProIPR001328. Pept_tRNA_hydro.
IPR018171. Pept_tRNA_hydro_CS.
[Graphical view]
PANTHERPTHR17224. PTHR17224. 1 hit.
PfamPF01195. Pept_tRNA_hydro. 1 hit.
[Graphical view]
SUPFAMSSF53178. Pept_tRNA_hydro. 1 hit.
TIGRFAMsTIGR00447. pth. 1 hit.
PROSITEPS01195. PEPT_TRNA_HYDROL_1. 1 hit.
PS01196. PEPT_TRNA_HYDROL_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC8U6W6_ECO10
AccessionPrimary (citable) accession number: C8U6W6
Entry history
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: May 1, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info