C8U226 (C8U226_ECO10) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Citrate synthase PIRNR PIRNR001369

Gene names

Name:	prpC EMBL BAI29184.1
Ordered Locus Names:	ECO103_0315 EMBL BAI29184.1

Organism

Escherichia coli O103:H2 (strain 12009 / EHEC) [Complete proteome] [HAMAP] EMBL BAI29184.1

Taxonomic identifier

585395 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli › Escherichia coli O103:H2

Protein attributes

Sequence length	389 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the citrate synthase family. RuleBase RU003406 PIRNR PIRNR001369

Ontologies

Keywords
Molecular function	Transferase RuleBase RU003406 PIRNR PIRNR001369 SAAS SAAS016143
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	cellular carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular_function	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	274	1	By similarity PIRSR PIRSR001369-1
	Active site	325	1	By similarity PIRSR PIRSR001369-1

Sequences

	Sequence		Length	Mass (Da)
	C8U226 [UniParc]. Last modified November 3, 2009. Version 1. Checksum: 947B5163C1E1EB24	FASTA	389	43,103
	10 20 30 40 50 60 MSDTTILQNS THVIKPKKSV ALSGVPAGNT ALCTVGKSGN DLHYRGYDIL DLAEHCEFEE 70 80 90 100 110 120 VAHLLIHGKL PTRDELAAYK TKLKALRGLP ANVRTVLEAL PAASHPMDVM RTGVSALGCT 130 140 150 160 170 180 LPEKEGHTVS GARDIADKLL ASLSSILLYW YHYSHNGERI QPETDDDSIG GHFLHLLHGE 190 200 210 220 230 240 KPSQSWEKAM HISLVLYAEH EFNASTFTSR VIAGTGSDMY SAIIGAIGAL RGPKHGGANE 250 260 270 280 290 300 VSLEIQQRYE TPDEAEADIR KRVENKEVVI GFGHPVYTIA DPRHQVIKRV AKQLSQEGGS 310 320 330 340 350 360 LKMYNIADRL ETVMWESKKM FPNLDWFSAV SYNMMGVPTE MFTPLFVIAR VTGWAAHIIE 370 380 QRQDNKIIRP SANYVGPEDR PFVALDKRQ

References

[1]

"Comparative genomics reveal the mechanism of the parallel evolution of O157 and non-O157 enterohemorrhagic Escherichia coli." Ogura Y., Ooka T., Iguchi A., Toh H., Asadulghani M., Oshima K., Kodama T., Abe H., Nakayama K., Kurokawa K., Tobe T., Hattori M., Hayashi T. Proc. Natl. Acad. Sci. U.S.A. 106:17939-17944(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 12009 / EHEC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP010958 Genomic DNA. Translation: BAI29184.1.
RefSeq	YP_003220318.1. NC_013353.1.
3D structure databases
ProteinModelPortal	C8U226.
ModBase	Search...
Protein-protein interaction databases
STRING	585395.ECO103_0315.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAI29184; BAI29184; ECO103_0315.
GeneID	8476411.
KEGG	eoh:ECO103_0315.
PATRIC	32092210. VBIEscCol146794_0330.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0372.
HOGENOM	HOG000021225.
KO	K01659.
OMA	HVIEYVE.
ProtClustDB	PRK12351.
Enzyme and pathway databases
BioCyc	ECOL585395:GJA9-325-MONOMER.
Family and domain databases
Gene3D	1.10.230.10. 1 hit. 1.10.580.10. 1 hit.
InterPro	IPR011278. 2-MeCitrate/Citrate_synth_I. IPR016142. Citrate_synth-like_lrg_a-sub. IPR016143. Citrate_synth-like_sm_a-sub. IPR002020. Citrate_synthase-like. IPR016141. Citrate_synthase-like_core. IPR019810. Citrate_synthase_AS. IPR024176. Citrate_synthase_bac-typ. [Graphical view]
PANTHER	PTHR11739. PTHR11739. 1 hit.
Pfam	PF00285. Citrate_synt. 1 hit. [Graphical view]
PIRSF	PIRSF001369. Citrate_synth. 1 hit.
PRINTS	PR00143. CITRTSNTHASE.
SUPFAM	SSF48256. Citrate_synthase_core. 1 hit.
TIGRFAMs	TIGR01800. cit_synth_II. 1 hit.
PROSITE	PS00480. CITRATE_SYNTHASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C8U226_ECO10

Accession

Primary (citable) accession number: C8U226

Entry history

Integrated into UniProtKB/TrEMBL:	November 3, 2009
Last sequence update:	November 3, 2009
Last modified:	May 1, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)