C8TPH1 (C8TPH1_ECO26) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Fused glucose-specific PTS enzymes: IIB component /IIC component EMBL BAI24735.1

Gene names

Name:	ptsG EMBL BAI24735.1
Ordered Locus Names:	ECO26_1434 EMBL BAI24735.1

Organism

Escherichia coli O26:H11 (strain 11368 / EHEC) [Complete proteome] [HAMAP] EMBL BAI24735.1

Taxonomic identifier

573235 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli › Escherichia coli O26:H11

Protein attributes

Sequence length	477 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate. SAAS SAAS011535
Sequence similarities	Contains 1 PTS EIIB type-1 domain. SAAS SAAS011535 Contains 1 PTS EIIC type-1 domain. SAAS SAAS018113

Ontologies

Keywords
Biological process	Phosphotransferase system SAAS SAAS011535 Sugar transport SAAS SAAS011535 Transport
Cellular component	Cell membrane SAAS SAAS011535 Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS011535
Molecular function	Kinase SAAS SAAS011535 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	glucose transmembrane transporter activity Inferred from electronic annotation. Source: InterPro kinase activity Inferred from electronic annotation. Source: UniProtKB-KW protein-N(PI)-phosphohistidine-sugar phosphotransferase activity Inferred from electronic annotation. Source: InterPro sugar:hydrogen symporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C8TPH1 [UniParc]. Last modified November 3, 2009. Version 1. Checksum: 1E9CA1FCA205A8C3	FASTA	477	50,721
	10 20 30 40 50 60 MFKNAFANLQ KVGKSLMLPV SVLPIAGILL GVGSANFSWL PAVVSHVMAE AGGSVFANMP 70 80 90 100 110 120 LIFAIGVALG FTNNDGVSAL AAVVAYGIMV KTMDVVAPLV LHLPAEEIAS KHLADTGVLG 130 140 150 160 170 180 GIISGAIAAY MFNRFYRIKL PEYLGFFAGK RFVPIISGLA AIFTGVVLSF IWPPIGSAIQ 190 200 210 220 230 240 TFSQWAAYQN PVVAFGIYGF IERCLVPFGL HHIWNVPFQM QIGEYTNAAG QVFHGDIPRY 250 260 270 280 290 300 MAGDPTAGKL SGGFLFKMYG LPAAAIAIWH SAKPENRAKV GGIMISAALT SFLTGITEPI 310 320 330 340 350 360 EFSFMFVAPI LYIIHAILAG LAFPICILLG MRDGTSFSHG LIDFIVLSGN SSKLWLFPIV 370 380 390 400 410 420 GIGYAIVYYT IFRVLIKALD LKTPGREDAT EDAKATGTSE MAPALVAAFG GKENITNLDA 430 440 450 460 470 CITRLRVSVA DVSKVDQAGL KKLGAAGVVV AGSGVQAIFG TKSDNLKTEM DEYIRNH

References

[1]

"Comparative genomics reveal the mechanism of the parallel evolution of O157 and non-O157 enterohemorrhagic Escherichia coli." Ogura Y., Ooka T., Iguchi A., Toh H., Asadulghani M., Oshima K., Kodama T., Abe H., Nakayama K., Kurokawa K., Tobe T., Hattori M., Hayashi T. Proc. Natl. Acad. Sci. U.S.A. 106:17939-17944(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 11368 / EHEC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP010953 Genomic DNA. Translation: BAI24735.1.
RefSeq	YP_003228475.1. NC_013361.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	573235.ECO26_1434.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAI24735; BAI24735; ECO26_1434.
GeneID	8483233.
KEGG	eoj:ECO26_1434.
PATRIC	18398419. VBIEscCol24965_1467.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1263.
HOGENOM	HOG000250993.
KO	K02778. K02779.
ProtClustDB	PRK11089.
Family and domain databases
Gene3D	3.30.1360.60. 1 hit.
InterPro	IPR018113. PTrfase_EIIB/Cys_phosph_CS. IPR004719. PTrfase_sys_maltose/Glc-sp_IIC. IPR001996. PTS_EIIB_1. IPR003352. PTS_EIIC. IPR013013. PTS_EIIC_1. IPR011535. PTS_Glc-like_IIB_component. IPR011299. PTS_IIBC_glc. [Graphical view]
Pfam	PF00367. PTS_EIIB. 1 hit. PF02378. PTS_EIIC. 1 hit. [Graphical view]
SUPFAM	SSF55604. PTS_EIIB. 1 hit.
TIGRFAMs	TIGR00826. EIIB_glc. 1 hit. TIGR00852. pts-Glc. 1 hit. TIGR02002. PTS-II-BC-glcB. 1 hit.
PROSITE	PS51098. PTS_EIIB_TYPE_1. 1 hit. PS01035. PTS_EIIB_TYPE_1_CYS. 1 hit. PS51103. PTS_EIIC_TYPE_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C8TPH1_ECO26

Accession

Primary (citable) accession number: C8TPH1

Entry history

Integrated into UniProtKB/TrEMBL:	November 3, 2009
Last sequence update:	November 3, 2009
Last modified:	May 1, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)