C8NMP8 (C8NMP8_COREF) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
2-oxoglutarate dehydrogenase E1 component EMBL EEW50133.1
EC=1.2.4.2 EMBL EEW50133.1

Gene names

Name:	odhA EMBL EEW50133.1
ORF Names:	HMPREF0290_1273 EMBL EEW50133.1

Organism

Corynebacterium efficiens YS-314 EMBL EEW50133.1

Taxonomic identifier

196164 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	1234 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the 2-oxoacid dehydrogenase family. RuleBase RU003423

Ontologies

Keywords
Ligand	Thiamine pyrophosphate SAAS SAAS001017
Molecular function	Oxidoreductase EMBL EEW50133.1
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular function	oxoglutarate dehydrogenase (succinyl-transferring) activity Inferred from electronic annotation. Source: EC thiamine pyrophosphate binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring acyl groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C8NMP8 [UniParc]. Last modified November 3, 2009. Version 1. Checksum: 1159885EF3B38768	FASTA	1,234	135,664
	10 20 30 40 50 60 MSSASTFGQN AWLVDEMFQQ FKKDPQSVDK EWRELFESQG GPQAEKATPA TPEAKKAASS 70 80 90 100 110 120 QSSTSGQSTA KAAPAAKTAP ASAPAKAAPV KQNQASKPAK KAKESPLSKP AAMPEPGTTP 130 140 150 160 170 180 LRGIFKSIAK NMDLSLEVPT ATSVRDMPAR LMFENRAMVN DQLKRTRGGK ISFTHIIGYA 190 200 210 220 230 240 MVKAVMAHPD MNNSYDIVDG KPSLVVPEHI NLGLAIDLPQ KDGSRALVVA AIKETEKMTF 250 260 270 280 290 300 SQFLEAYEDV VARSRVGKLT MDDYQGVTIS LTNPGGIGTR HSIPRLTKGQ GTIIGVGSMD 310 320 330 340 350 360 YPAEFQGASE DRLAELGVGK LVTITSTYDH RVIQGAESGE FLRTMSQLLV DDAFWDHIFE 370 380 390 400 410 420 EMNVPYTPMR WAQDLPNTGV DKNTRVMQLI EAYRSRGHLI ADTNPLPWVQ PGMPVPDHRD 430 440 450 460 470 480 LDIETHGLTL WDLDRTFHVG GFGGKETMTL REVLSRLRAA YTLKVGSEYT HILDRDERTW 490 500 510 520 530 540 LQDRLEAGMP KPTAAEQKYI LQKLNAAEAF ENFLQTKYVG QKRFSLEGAE SLIPLMDSAI 550 560 570 580 590 600 DTAAGQGLDE VVIGMPHRGR LNVLFNIVGK PLASIFNEFE GQMEQGQIGG SGDVKYHLGS 610 620 630 640 650 660 EGTHLQMFGD GEIKVSLTAN PSHLEAVNPV VEGIVRAKQD ILDKGPDGYT VVPLLLHGDA 670 680 690 700 710 720 AFAGLGIVPE TINLAALRGY DVGGTIHIVV NNQIGFTTTP DSSRSMHYAT DCAKAFGCPV 730 740 750 760 770 780 FHVNGDDPEA VVWVGQLATE YRRRFGKDVF IDLICYRLRG HNEADDPSMT QPKMYELITG 790 800 810 820 830 840 RDSVRATYTE DLLGRGDLSP EDAEAVVRDF HDQMESVFNE VKEAGKKQPD EQTGITGSQE 850 860 870 880 890 900 LTRGLDTNIT REELVELGQA FVNTPEGFTY HPRVAPVAKK RAESVTEGGI DWAWGELIAF 910 920 930 940 950 960 GSLATSGRLV RLAGEDSRRG TFTQRHAVAI DPNTAEEFNP LHELAQAKGG GKFLVYNSAL 970 980 990 1000 1010 1020 TEYAGMGFEY GYSVGNPDAV VSWEAQFGDF ANGAQTIIDE YISSGEAKWG QTSSVILLLP 1030 1040 1050 1060 1070 1080 HGYEGQGPDH SSARIERFLQ LCAEGSMTIA QPTTPANYFH LLRRHALGKM KRPLVVFTPK 1090 1100 1110 1120 1130 1140 SMLRNKAATS APEEFTEVTR FKSVIDDPNV ADASKVKKIM LCSGKIYYEL AKRKEKDNRD 1150 1160 1170 1180 1190 1200 DIAIVRIEML HPIPFNRLRD AFDGYPNAEE ILFVQDEPAN QGAWPFYQEH LPNLIEGMLP 1210 1220 1230 MRRISRRSQS STATGIAKVH TIEQQKLLDD AFNA

References

[1]

Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V., Kovar C., Mata R., Mathew T., Ngo R. , Nguyen L., Nguyen N., Okwuonu G., Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A., Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C., Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S., Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S., Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L., Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P., Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K., Petrosino J., Highlander S., Gibbs R. Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: YS-314 EMBL EEW50133.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	ACLI01000069 Genomic DNA. Translation: EEW50133.1.
RefSeq	NP_737800.1. NC_004369.1.
3D structure databases
ProteinModelPortal	C8NMP8.
ModBase	Search...
Protein-protein interaction databases
STRING	C8NMP8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1031967.
PATRIC	21488508. VBICorEff9312_1188.
Phylogenomic databases
OMA	EGDEPAF.
ProtClustDB	PRK12270.
Family and domain databases
InterPro	IPR001078. 2-oxoacid_DH_actylTfrase. IPR011603. 2oxoglutarate_DH_E1. IPR023213. CAT-like_dom. IPR001017. DH_E1. IPR005475. Transketolase-like_Pyr-bd. [Graphical view]
Gene3D	G3DSA:3.30.559.10. CAT-like_dom. 1 hit.
PANTHER	PTHR23152. 2oxoglutarate_DH_E1. 1 hit.
Pfam	PF00198. 2-oxoacid_dh. 1 hit. PF00676. E1_dh. 1 hit. PF02779. Transket_pyr. 1 hit. [Graphical view]
PIRSF	PIRSF000157. Oxoglu_dh_E1. 1 hit.
SMART	SM00861. Transket_pyr. 1 hit. [Graphical view]
TIGRFAMs	TIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C8NMP8_COREF

Accession

Primary (citable) accession number: C8NMP8

Entry history

Integrated into UniProtKB/TrEMBL:	November 3, 2009
Last sequence update:	November 3, 2009
Last modified:	December 14, 2011
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)