C8N258 (C8N258_STAAU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Fructose-bisphosphate aldolase class 1 HAMAP MF_00729
EC=4.1.2.13 HAMAP MF_00729

Alternative name(s):
Fructose-biphosphate aldolase class I HAMAP MF_00729

Gene names

Name:	fda HAMAP MF_00729
ORF Names:	SAOG_01600 EMBL EEV26699.1

Organism

Staphylococcus aureus A9781 EMBL EEV26699.1

Taxonomic identifier

553596 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	296 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate. HAMAP MF_00729
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4. HAMAP MF_00729
Sequence similarities	Belongs to the class I fructose-bisphosphate aldolase family. HAMAP MF_00729

Ontologies

Keywords
Biological process	Glycolysis HAMAP MF_00729
Ligand	Schiff base HAMAP MF_00729
Molecular function	Lyase HAMAP MF_00729
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: HAMAP
Molecular function	fructose-bisphosphate aldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	175	1	Proton acceptor By similarity HAMAP MF_00729
	Active site	212	1	Schiff-base intermediate with dihydroxyacetone-P By similarity HAMAP MF_00729

Sequences

	Sequence		Length	Mass (Da)
	C8N258 [UniParc]. Last modified November 3, 2009. Version 1. Checksum: D63B1A3C7646725B	FASTA	296	33,042
	10 20 30 40 50 60 MNKEQLEKMK NGKGFIAALD QSGGSTPKAL KEYGVNEDQY SNEDEMFQLV HDMRTRVVTS 70 80 90 100 110 120 PSFSPDKILG AILFEQTMDR EVEGKYTADY LADKGVVPFL KVDKGLAEEQ NGVQLMKPID 130 140 150 160 170 180 NLDSLLDRAN ERHIFGTKMR SNILELNEQG IKDVVEQQFE VAKQIIAKGL VPIIEPEVNI 190 200 210 220 230 240 NAKDKAEIEK VLKAELKKGL DSLNADQLVM LKLTIPTEPN LYKELAEHPN VVRVVVLSGG 250 260 270 280 290 YSREKANELL KDNDELIASF SRALASDLRA DQSKEEFDKA LGDAVESIYD ASVNKN

References

[1]

"The Genome Sequence of Staphylococcus aureus strain A9781." The Broad Institute Genome Sequencing Platform Ward D., Young S.K., Zeng Q., Koehrsen M., Godfrey P., Alvarado L., Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C. , Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Peleg A.Y., Galagan J., Nusbaum C., Birren B. Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: A9781 EMBL EEV26699.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	ACKL01000031 Genomic DNA. Translation: EEV26699.1.
3D structure databases
ProteinModelPortal	C8N258.
SMR	C8N258. Positions 1-294.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	26198053. VBIStaAur77373_1273.
Family and domain databases
HAMAP	MF_00729. FBP_aldolase_1. [Tree]
InterPro	IPR000741. Aldolase_I. IPR013785. Aldolase_TIM. IPR023014. FBP_aldolase_I_bac. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
Pfam	PF00274. Glycolytic. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C8N258_STAAU

Accession

Primary (citable) accession number: C8N258

Entry history

Integrated into UniProtKB/TrEMBL:	November 3, 2009
Last sequence update:	November 3, 2009
Last modified:	December 14, 2011
This is version 7 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)