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Protein
Submitted name:

IgG-binding protein

Gene

SAHG_00235

Organism
Staphylococcus aureus A6224
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  1. pathogenesis Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
IgG-binding proteinImported
Gene namesi
ORF Names:SAHG_00235Imported
OrganismiStaphylococcus aureus A6224Imported
Taxonomic identifieri553568 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2WY7X-ray1.70Q198-266[»]
2WY8X-ray1.70Q198-266[»]
ProteinModelPortaliC8LN82.
SMRiC8LN82. Positions 47-89, 97-130, 198-266.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiC8LN82.

Family & Domainsi

Family and domain databases

InterProiIPR009063. Ig/albumin-bd.
IPR021657. IgG-binding_Sbi_domIV.
IPR003132. Protein_A_Ig-bd.
[Graphical view]
PfamiPF02216. B. 2 hits.
PF11621. Sbi-IV. 1 hit.
[Graphical view]
SUPFAMiSSF46997. SSF46997. 2 hits.

Sequencei

Sequence statusi: Complete.

C8LN82-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKNKYISKLL VGAATITLAT MISNGEAKAS ENTQQTSTKH QTTQNNYVTD
60 70 80 90 100
QQKAFYQVLH LKGITEEQRN QYIKTLREHP ERAQEVFSES LKDSKNPDRR
110 120 130 140 150
VAQQNAFYNV LKNDNLTEQE KNNYIAQIKE NPDRSQQVWV ESVQSSKAKE
160 170 180 190 200
RQNIENADKA IKDFQDNKAP HDKSAAYEAN SKLPKDLRDK NNRFVEKVSI
210 220 230 240 250
EKAIVRHDER VKSANDAISK LNEKDSIENR RLAQREVNKA PMDVKEHLQK
260 270 280 290 300
QLDALVAQKD AEKKVAPKVE APQIQSPQIE KPKAESPKVE VPQSKLLGYY
310 320 330 340 350
QSLKDSFNYG YKYLTDTYKS YKEKYDTAKY YYNTYYKYKG AIDQTVLTVL
360 370 380 390 400
GSGSKSYIQP LKVDDKNGYL AKSYAQVRNY VTESINTGKV LYTFYQNPTL
410 420
VKTAIKAQET ASSIKNTLSN LLSFWK
Length:426
Mass (Da):48,936
Last modified:November 3, 2009 - v1
Checksum:iE61F85563B118AEE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACKE01000047 Genomic DNA. Translation: EEV79401.1.

Genome annotation databases

EnsemblBacteriaiEEV79401; EEV79401; SAHG_00235.
PATRICi29482945. VBIStaAur3166_2751.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACKE01000047 Genomic DNA. Translation: EEV79401.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2WY7X-ray1.70Q198-266[»]
2WY8X-ray1.70Q198-266[»]
ProteinModelPortaliC8LN82.
SMRiC8LN82. Positions 47-89, 97-130, 198-266.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiEEV79401; EEV79401; SAHG_00235.
PATRICi29482945. VBIStaAur3166_2751.

Miscellaneous databases

EvolutionaryTraceiC8LN82.

Family and domain databases

InterProiIPR009063. Ig/albumin-bd.
IPR021657. IgG-binding_Sbi_domIV.
IPR003132. Protein_A_Ig-bd.
[Graphical view]
PfamiPF02216. B. 2 hits.
PF11621. Sbi-IV. 1 hit.
[Graphical view]
SUPFAMiSSF46997. SSF46997. 2 hits.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: A6224Imported.
  2. "A structural basis for Staphylococcal complement subversion: X-ray structure of the complement-binding domain of Staphylococcus aureus protein Sbi in complex with ligand C3d."
    Clark E.A., Crennell S., Upadhyay A., Zozulya A.V., Mackay J.D., Svergun D.I., Bagby S., van den Elsen J.M.
    Mol. Immunol. 48:452-462(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS) OF 198-266.
  3. "Serine/threonine phosphatase Stp1 contributes to reduced susceptibility to vancomycin and virulence in Staphylococcus aureus."
    Cameron D.R., Ward D.V., Kostoulias X., Howden B.P., Moellering R.C.Jr., Eliopoulos G.M., Peleg A.Y.
    J. Infect. Dis. 205:1677-1687(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: A6224Imported.

Entry informationi

Entry nameiC8LN82_STAAU
AccessioniPrimary (citable) accession number: C8LN82
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: January 7, 2015
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

3D-structureCombined sources

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.