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C8CHS6

- C8CHS6_RAT

UniProt

C8CHS6 - C8CHS6_RAT

Protein
Submitted name:

Mitochondrial superoxide dismutase 2

Gene

Sod2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. metal ion binding Source: InterPro
    2. superoxide dismutase activity Source: InterPro

    GO - Biological processi

    1. age-dependent response to reactive oxygen species Source: Ensembl
    2. detection of oxygen Source: Ensembl
    3. erythrophore differentiation Source: Ensembl
    4. glutathione metabolic process Source: Ensembl
    5. heart development Source: Ensembl
    6. hemopoiesis Source: Ensembl
    7. intrinsic apoptotic signaling pathway in response to DNA damage Source: Ensembl
    8. intrinsic apoptotic signaling pathway in response to oxidative stress Source: Ensembl
    9. iron ion homeostasis Source: Ensembl
    10. liver development Source: Ensembl
    11. locomotory behavior Source: Ensembl
    12. negative regulation of fat cell differentiation Source: Ensembl
    13. negative regulation of fibroblast proliferation Source: Ensembl
    14. negative regulation of neuron apoptotic process Source: Ensembl
    15. negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway Source: Ensembl
    16. neuron development Source: Ensembl
    17. oxygen homeostasis Source: Ensembl
    18. positive regulation of nitric oxide biosynthetic process Source: Ensembl
    19. post-embryonic development Source: Ensembl
    20. protein homotetramerization Source: Ensembl
    21. regulation of catalytic activity Source: Ensembl
    22. regulation of mitochondrial membrane potential Source: Ensembl
    23. regulation of transcription from RNA polymerase II promoter Source: Ensembl
    24. release of cytochrome c from mitochondria Source: Ensembl
    25. respiratory electron transport chain Source: Ensembl
    26. response to activity Source: Ensembl
    27. response to axon injury Source: Ensembl
    28. response to gamma radiation Source: Ensembl
    29. response to hydrogen peroxide Source: Ensembl
    30. response to hyperoxia Source: Ensembl
    31. superoxide anion generation Source: Ensembl
    32. vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Mitochondrial superoxide dismutase 2Imported
    Gene namesi
    Name:Sod2Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    Organism-specific databases

    RGDi3732. Sod2.

    Subcellular locationi

    GO - Cellular componenti

    1. mitochondrial inner membrane Source: Ensembl

    Interactioni

    Protein-protein interaction databases

    STRINGi10116.ENSRNOP00000025794.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the iron/manganese superoxide dismutase family.UniRule annotation

    Family and domain databases

    InterProiIPR001189. Mn/Fe_SOD.
    IPR019831. Mn/Fe_SOD_N.
    [Graphical view]
    PANTHERiPTHR11404. PTHR11404. 1 hit.
    PfamiPF00081. Sod_Fe_N. 1 hit.
    [Graphical view]
    PRINTSiPR01703. MNSODISMTASE.
    SUPFAMiSSF46609. SSF46609. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    C8CHS6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLCRAACSAG RRLGPAASTA GSRHKHSLPD LPYDYGALEP HINAQIMQLH   50
    HSKHHATYVN NLNVTEEKYH EA 72
    Length:72
    Mass (Da):7,988
    Last modified:October 13, 2009 - v1
    Checksum:i0A7BCC5B21AF1DCD
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei72 – 721Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GQ404503 mRNA. Translation: ACV32533.1.
    UniGeneiRn.10488.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GQ404503 mRNA. Translation: ACV32533.1 .
    UniGenei Rn.10488.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10116.ENSRNOP00000025794.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    RGDi 3732. Sod2.

    Miscellaneous databases

    NextBioi 35565364.

    Family and domain databases

    InterProi IPR001189. Mn/Fe_SOD.
    IPR019831. Mn/Fe_SOD_N.
    [Graphical view ]
    PANTHERi PTHR11404. PTHR11404. 1 hit.
    Pfami PF00081. Sod_Fe_N. 1 hit.
    [Graphical view ]
    PRINTSi PR01703. MNSODISMTASE.
    SUPFAMi SSF46609. SSF46609. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Rana T., Das S., Bera A.K., Pan D., De S., Sikdar S., Bandyopadhyay S., Bhattacharya D., Das S.K.
      Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: WImported.

    Entry informationi

    Entry nameiC8CHS6_RAT
    AccessioniPrimary (citable) accession number: C8CHS6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 13, 2009
    Last sequence update: October 13, 2009
    Last modified: October 1, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)