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C8CHS6

- C8CHS6_RAT

UniProt

C8CHS6 - C8CHS6_RAT

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Protein
Submitted name:

Mitochondrial superoxide dismutase 2

Gene

Sod2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. metal ion binding Source: InterPro
  2. superoxide dismutase activity Source: InterPro

GO - Biological processi

  1. age-dependent response to reactive oxygen species Source: Ensembl
  2. detection of oxygen Source: Ensembl
  3. erythrophore differentiation Source: Ensembl
  4. glutathione metabolic process Source: Ensembl
  5. heart development Source: Ensembl
  6. hemopoiesis Source: Ensembl
  7. intrinsic apoptotic signaling pathway in response to DNA damage Source: Ensembl
  8. intrinsic apoptotic signaling pathway in response to oxidative stress Source: Ensembl
  9. iron ion homeostasis Source: Ensembl
  10. liver development Source: Ensembl
  11. locomotory behavior Source: Ensembl
  12. negative regulation of fat cell differentiation Source: Ensembl
  13. negative regulation of fibroblast proliferation Source: Ensembl
  14. negative regulation of neuron apoptotic process Source: Ensembl
  15. negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway Source: Ensembl
  16. neuron development Source: Ensembl
  17. oxygen homeostasis Source: Ensembl
  18. positive regulation of nitric oxide biosynthetic process Source: Ensembl
  19. post-embryonic development Source: Ensembl
  20. protein homotetramerization Source: Ensembl
  21. regulation of catalytic activity Source: Ensembl
  22. regulation of mitochondrial membrane potential Source: Ensembl
  23. regulation of transcription from RNA polymerase II promoter Source: Ensembl
  24. release of cytochrome c from mitochondria Source: Ensembl
  25. respiratory electron transport chain Source: Ensembl
  26. response to activity Source: Ensembl
  27. response to axon injury Source: Ensembl
  28. response to gamma radiation Source: Ensembl
  29. response to hydrogen peroxide Source: Ensembl
  30. response to hyperoxia Source: Ensembl
  31. superoxide anion generation Source: Ensembl
  32. vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Mitochondrial superoxide dismutase 2Imported
Gene namesi
Name:Sod2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi3732. Sod2.

Subcellular locationi

GO - Cellular componenti

  1. extracellular vesicular exosome Source: Ensembl
  2. mitochondrial inner membrane Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiC8CHS6. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000025794.

Family & Domainsi

Sequence similaritiesi

Belongs to the iron/manganese superoxide dismutase family.UniRule annotation

Family and domain databases

InterProiIPR001189. Mn/Fe_SOD.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERiPTHR11404. PTHR11404. 1 hit.
PfamiPF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.

Sequencei

Sequence statusi: Fragment.

C8CHS6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLCRAACSAG RRLGPAASTA GSRHKHSLPD LPYDYGALEP HINAQIMQLH
60 70
HSKHHATYVN NLNVTEEKYH EA
Length:72
Mass (Da):7,988
Last modified:October 13, 2009 - v1
Checksum:i0A7BCC5B21AF1DCD
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei72 – 721Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
GQ404503 mRNA. Translation: ACV32533.1.
UniGeneiRn.10488.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
GQ404503 mRNA. Translation: ACV32533.1 .
UniGenei Rn.10488.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10116.ENSRNOP00000025794.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

RGDi 3732. Sod2.

Miscellaneous databases

NextBioi 35565364.

Gene expression databases

ExpressionAtlasi C8CHS6. baseline and differential.

Family and domain databases

InterProi IPR001189. Mn/Fe_SOD.
IPR019831. Mn/Fe_SOD_N.
[Graphical view ]
PANTHERi PTHR11404. PTHR11404. 1 hit.
Pfami PF00081. Sod_Fe_N. 1 hit.
[Graphical view ]
PRINTSi PR01703. MNSODISMTASE.
SUPFAMi SSF46609. SSF46609. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Rana T., Das S., Bera A.K., Pan D., De S., Sikdar S., Bandyopadhyay S., Bhattacharya D., Das S.K.
    Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: WImported.

Entry informationi

Entry nameiC8CHS6_RAT
AccessioniPrimary (citable) accession number: C8CHS6
Entry historyi
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: October 29, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)