Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Bone morphogenetic protein 2

Gene

BMP2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Bone morphogenetic protein 2Imported
Gene namesi
Name:BMP2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence analysisAdd
BLAST
Chaini24 – 11592Sequence analysisPRO_5007649280Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000368104.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini42 – 11574TGFb_propeptideInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3900. Eukaryota.
ENOG410XT8Z. LUCA.

Family and domain databases

InterProiIPR001111. TGF-b_N.
IPR015615. TGF-beta-rel.
[Graphical view]
PANTHERiPTHR11848. PTHR11848. 1 hit.
PfamiPF00688. TGFb_propeptide. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

C8C069-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVAGTRCLLA LLLPQVLLGG AAGLVPELGR RKFAAASSGR PSSQPSDEVL
60 70 80 90 100
SEFELRLLSM FGLKQRPTPS RDAVVPPYML DLYRRHSGQP GSPAPDHRLE
110
RAASRANTVR SFHHE
Length:115
Mass (Da):12,527
Last modified:October 13, 2009 - v1
Checksum:i51555961B14D43DB
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei115 – 1151Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GQ335538 Genomic DNA. Translation: ACV32594.1.
GQ335539 Genomic DNA. Translation: ACV32595.1.
UniGeneiHs.73853.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GQ335538 Genomic DNA. Translation: ACV32594.1.
GQ335539 Genomic DNA. Translation: ACV32595.1.
UniGeneiHs.73853.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000368104.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG3900. Eukaryota.
ENOG410XT8Z. LUCA.

Miscellaneous databases

ChiTaRSiBMP2. human.

Family and domain databases

InterProiIPR001111. TGF-b_N.
IPR015615. TGF-beta-rel.
[Graphical view]
PANTHERiPTHR11848. PTHR11848. 1 hit.
PfamiPF00688. TGFb_propeptide. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Identification of BMP2 polymorphisms putatively involved in orofacial cleft."
    Prada-Arismendy J., Escobar L.M., Tellez C., Restrepo C., Castellanos J.E.
    Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiC8C069_HUMAN
AccessioniPrimary (citable) accession number: C8C069
Entry historyi
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: July 6, 2016
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.