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C7ZJ53 (C7ZJ53_NECH7) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length496 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively By similarity. PIRNR PIRNR038800

Catalytic activity

L-3-hydroxykynurenine + H2O = 3-hydroxyanthranilate + L-alanine. PIRNR PIRNR038800

L-kynurenine + H2O = anthranilate + L-alanine. PIRNR PIRNR038800

Cofactor

Pyridoxal phosphate By similarity. PIRNR PIRNR038800

Pathway

Amino-acid degradation; L-kynurenine degradation; L-alanine and anthranilate from L-kynurenine: step 1/1. PIRNR PIRNR038800

Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 2/3. PIRNR PIRNR038800

Subunit structure

Homodimer By similarity. PIRNR PIRNR038800

Subcellular location

Cytoplasm By similarity PIRNR PIRNR038800.

Sequence similarities

Belongs to the kynureninase family. PIRNR PIRNR038800

Sequences

Sequence LengthMass (Da)Tools
C7ZJ53 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: 8FA291034D95655B

FASTA49655,011
        10         20         30         40         50         60 
MELSGFVDRL RSGASPKFPQ DANSLEFARH LDSQDKLSHL RDEFVIPTKR SLKKKALDGS 

        70         80         90        100        110        120 
IPSHGASSNG TNGTNGHSNG HNGSSDDSEQ CLYFVGNSLG AQPKAVREYL NAQLETWASI 

       130        140        150        160        170        180 
GVNGHFSAMG NSPLTPWQDM AEDCAIKSAD IVGASPSEIV IMNTLTANLH FLMASFYKPN 

       190        200        210        220        230        240 
EKRHKIILEW KPFPSDHYAI ESQVVWHGLD PEKSMVKIHP NDDFIITTDL ILSTIDEHAE 

       250        260        270        280        290        300 
DTALLLLPGI QYYSGQLFDI PRITAYAQER GIVVGWDLAH AAGNVELKLH DWNVDFACWC 

       310        320        330        340        350        360 
TYKYINAGPG SIAGAYVHEK HGKVEFKDDS GKPTYRPRLM GWYGGDKSVR FNMDNKFVPT 

       370        380        390        400        410        420 
VGAGGFQLSN PSAIDLASLS GALSVFNKTK MYEIRSKALV LTAYAEHLLD QIISESSDET 

       430        440        450        460        470        480 
PLFRIITPRD PAQRGTQLSV LLREGLMERV SEALEENGVI CDKRKPDVIR VAPVPLYTRF 

       490 
EDVWKFMQVL RGALSQ 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
GG698932 Genomic DNA. Translation: EEU35954.1.
RefSeqXP_003041667.1. XM_003041621.1.

3D structure databases

ProteinModelPortalC7ZJ53.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiNechaT49794; NechaP49794; NechaG49794.
GeneID9674071.
KEGGnhe:NECHADRAFT_49794.

Phylogenomic databases

KOK01556.
OrthoDBEOG7V1G0J.

Enzyme and pathway databases

UniPathwayUPA00253; UER00329.
UPA00334; UER00455.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
HAMAPMF_01970. Kynureninase.
InterProIPR000192. Aminotrans_V/Cys_dSase.
IPR010111. Kynureninase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERPTHR14084. PTHR14084. 1 hit.
PfamPF00266. Aminotran_5. 1 hit.
[Graphical view]
PIRSFPIRSF038800. KYNU. 1 hit.
SUPFAMSSF53383. SSF53383. 2 hits.
TIGRFAMsTIGR01814. kynureninase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC7ZJ53_NECH7
AccessionPrimary (citable) accession number: C7ZJ53
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: February 19, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)