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Protein

DNA ligase

Gene

NECHADRAFT_43928

Organism
Nectria haematococca (strain 77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVI) (Fusarium solani subsp. pisi)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:NECHADRAFT_43928Imported
OrganismiNectria haematococca (strain 77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVI) (Fusarium solani subsp. pisi)Imported
Taxonomic identifieri660122 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeHypocrealesNectriaceaeFusariumFusarium solani species complex
ProteomesiUP000005206 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliC7Z9K8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

InParanoidiC7Z9K8.
KOiK10777.
OrthoDBiEOG7QC84G.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR029710. LIG4.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PANTHERiPTHR10459:SF7. PTHR10459:SF7. 1 hit.
PfamiPF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 2 hits.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C7Z9K8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSQQEQRPQ TEDAKHEDEI QYGTVGITQE EMEEKYPNRP KNHSKTLVFS
60 70 80 90 100
ELFRELFNPL SENKKQNATG AGPRKAFRGV NKLSPHEQRR HIIERFIIRW
110 120 130 140 150
RKEVGPDFYP ALRLILPDKD RDRGVYGLKE NAIGKLLVKL MKIDKSSEDG
160 170 180 190 200
YNLLHWKLPG QTTASRLAGD FAGRCFEVIS KRPMRTTVGT MTIAEVNEQL
210 220 230 240 250
DKLAASTGET ENLRIFETFY NHMNAEELMW LIRIVLKQMK VGATEKTFLD
260 270 280 290 300
LWHPDGDALF SVSSSLRRVC WELSDPEIRL EQDEAGVALL QCFQPQLAQF
310 320 330 340 350
QMPASFQKMI QLLRPTEEDP EFWIEEKLDG ERMQMHMVED KKHPGGRRFC
360 370 380 390 400
FWSRKAKDYT YLYGDGLQDE NSSLTRHLKK AFASGVKNLI LDGEMITWDM
410 420 430 440 450
GVDKIVPFGT LKTAALAEQQ NKSDTNSAGH RPLFRVFDIL YLNNKPLTQY
460 470 480 490 500
TLRDRHRALE KAVKSVHRRL EIHNYTSATT SDAIEPLLRE VVANASEGLV
510 520 530 540 550
LKNPRSMYRL NHRNDDWLKV KPEYMSEFGE SLDCVIIGGY YGSGKRGGML
560 570 580 590 600
SSYLCGLRVT QNHIQAGANP EKCFSFFKVG GGFRAEDYAE IRHRTEGKWI
610 620 630 640 650
EWDQKNPPSE YIELGGGELR QYERPDMWIR PKDSVVVSVK AASVGPSDQF
660 670 680 690 700
ARGFTLRFPR FRRLRLDRTW DTALSLEEFQ ELKDRVDEES KEKAMTVEDR
710 720 730 740 750
KRRNPKRIKR ELVIAGEDSA PVEFEGEKTK LFEGLEFCVL SEALKPYKKT
760 770 780 790 800
KTQLESIIKE NGGTISQRAA PGTNMVLIAD KKVVKVASLM KGGDVDLIRP
810 820 830 840 850
KWIKDCLEQD LGQFLLPFEE SHLFHATEAM KRAAEQNTDQ FGDSYARDMS
860 870 880 890 900
IDELKDLMDC MPKIEDGEPF NKNEFLQQLE DHGKDLGNLR SFIFRRCVVL
910 920 930 940 950
FHGVDTGINR VSRLKHFVKY GGGSVTEDAG DLSVTHVVIE GGDPMQMGEA
960 970 980 990
ADMVRKELSS RRTQPRVVAG KWIEDCWKEG TLLDEEQFVV P
Length:991
Mass (Da):113,609
Last modified:October 13, 2009 - v1
Checksum:i7B28DF6B926BF1CC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG698912 Genomic DNA. Translation: EEU39116.1.
RefSeqiXP_003044829.1. XM_003044783.1.

Genome annotation databases

EnsemblFungiiNechaT43928; NechaP43928; NechaG43928.
GeneIDi9673470.
KEGGinhe:NECHADRAFT_43928.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG698912 Genomic DNA. Translation: EEU39116.1.
RefSeqiXP_003044829.1. XM_003044783.1.

3D structure databases

ProteinModelPortaliC7Z9K8.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiNechaT43928; NechaP43928; NechaG43928.
GeneIDi9673470.
KEGGinhe:NECHADRAFT_43928.

Phylogenomic databases

InParanoidiC7Z9K8.
KOiK10777.
OrthoDBiEOG7QC84G.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR029710. LIG4.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PANTHERiPTHR10459:SF7. PTHR10459:SF7. 1 hit.
PfamiPF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 2 hits.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVIImported.

Entry informationi

Entry nameiC7Z9K8_NECH7
AccessioniPrimary (citable) accession number: C7Z9K8
Entry historyi
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: July 22, 2015
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.