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Protein

DNA ligase

Gene

NECHADRAFT_95596

Organism
Nectria haematococca (strain 77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVI) (Fusarium solani subsp. pisi)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:NECHADRAFT_95596Imported
OrganismiNectria haematococca (strain 77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVI) (Fusarium solani subsp. pisi)Imported
Taxonomic identifieri660122 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeHypocrealesNectriaceaeFusariumFusarium solani species complex
ProteomesiUP000005206: Unassembled WGS sequence

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

InParanoidiC7YYZ1.
KOiK10747.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 2 hits.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C7YYZ1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAPKQATLGK FFGAKGAAPV RQTTLSFSTK AKKEEAEEGE ADVSTNGSKA
60 70 80 90 100
DKADKKAEAE SAPIKKEEAE EDSDGPVTKR ARRSRKRVEE EDDDISDEPV
110 120 130 140 150
KKKTPSPKKR KSASPSPKPT PTKKSKARAV KEPAAEEEDE PVKDEASTAS
160 170 180 190 200
ASEAEDDAEV EEEKPEVAAK ARQKAQTKLK TKTKEKDPYP DWEAGTPVPY
210 220 230 240 250
AALCTTFSLI EMTTKRLIIM EHCSLFLRQV MRLTPNDLLP TVLLMINKLA
260 270 280 290 300
PDYAGIELGI GESLIMKAIG ETTGRSLQVI KADQKEIGDL GLVAVKSRST
310 320 330 340 350
QRTMFKPKAL TIRGVHQGLM NIATVTGNGA QGRKVDGIKK LLAAADANST
360 370 380 390 400
GKVDITKDKG GPSEAKFIIR FLEGKLRLGL AEKTVLVSLA QAIVCHEADA
410 420 430 440 450
KDKVPSTSDI EKGESILKTV YSELPSYDVI IPAILEHGIM KLRENCNLRP
460 470 480 490 500
GVPLKPMLAK PTKAITEVLD RFEGQTFTCE YKYDGERAQI HYVAKDAPQQ
510 520 530 540 550
LSQASQGAAK EVGAGVASIF SRNSEDLSKK YPDILAKLST WVKPDTKSFV
560 570 580 590 600
LDCETVAWDV DEKKVLPFQQ LMTRKKKDVK VEDVKVKVCV FAFDLLYLNG
610 620 630 640 650
EAVVERALRE RRELLEAAFI PVEGEFAFAT HMNGQELEEI QVFLDESVKA
660 670 680 690 700
SCEGLMVKML DGRESGYEPS KRSRNWLKIK KDYLSGVGDS LDLVVLGAYY
710 720 730 740 750
GKGKRTSVYG AFLLACYNPN SDTYETVCNI GTGFSEQVLE DLHKQLSEIT
760 770 780 790 800
IDRPKPFYSH SSGGQHQPDV WFEPRYVWEV KTADLTLSPR YKAGAKEGVD
810 820 830 840 850
PSGTKGISLR FPRFIRIRDD KNADSATTSR QVAEMYRKQE SVSKSKGPAV

DDDFEY
Length:856
Mass (Da):94,486
Last modified:October 13, 2009 - v1
Checksum:i8A8FAB7B27E3279E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG698903 Genomic DNA. Translation: EEU43085.1.
RefSeqiXP_003048798.1. XM_003048752.1.

Genome annotation databases

EnsemblFungiiNechaT95596; NechaP95596; NechaG95596.
GeneIDi9665645.
KEGGinhe:NECHADRAFT_95596.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG698903 Genomic DNA. Translation: EEU43085.1.
RefSeqiXP_003048798.1. XM_003048752.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiNechaT95596; NechaP95596; NechaG95596.
GeneIDi9665645.
KEGGinhe:NECHADRAFT_95596.

Phylogenomic databases

InParanoidiC7YYZ1.
KOiK10747.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 2 hits.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVIImported.

Entry informationi

Entry nameiC7YYZ1_NECH7
AccessioniPrimary (citable) accession number: C7YYZ1
Entry historyi
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: January 7, 2015
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.