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Protein

Histone-lysine N-methyltransferase

Gene

SDG2102

Organism
Nectria haematococca (strain 77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVI) (Fusarium solani subsp. pisi)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N6-methyl-L-lysine-[histone].PROSITE-ProRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotationSAAS annotation, Transferase
LigandS-adenosyl-L-methioninePROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferasePROSITE-ProRule annotation (EC:2.1.1.43PROSITE-ProRule annotation)
Gene namesi
Name:SDG2102Imported
ORF Names:NECHADRAFT_106311Imported
OrganismiNectria haematococca (strain 77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVI) (Fusarium solani subsp. pisi)Imported
Taxonomic identifieri660122 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeHypocrealesNectriaceaeFusariumFusarium solani species complex
Proteomesi
  • UP000005206 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi140110.NechaP106311

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini120 – 174AWSInterPro annotationAdd BLAST55
Domaini176 – 293SETInterPro annotationAdd BLAST118
Domaini300 – 316Post-SETInterPro annotationAdd BLAST17
Domaini415 – 491TFIIS N-terminalInterPro annotationAdd BLAST77
Domaini565 – 597WWInterPro annotationAdd BLAST33

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili865 – 899Sequence analysisAdd BLAST35

Sequence similaritiesi

Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

InParanoidiC7YYN9
KOiK11423
OrthoDBiEOG092C3T9B

Family and domain databases

CDDicd00201 WW, 1 hit
Gene3Di1.10.1740.1001 hit
1.20.930.101 hit
InterProiView protein in InterPro
IPR006560 AWS_dom
IPR025788 Hist-Lys_N-MeTrfase_SET2_fun
IPR003616 Post-SET_dom
IPR001214 SET_dom
IPR013257 SRI
IPR038190 SRI_sf
IPR035441 TFIIS/LEDGF_dom_sf
IPR017923 TFIIS_N
IPR001202 WW_dom
IPR036020 WW_dom_sf
PfamiView protein in Pfam
PF08711 Med26, 1 hit
PF00856 SET, 1 hit
PF08236 SRI, 1 hit
SMARTiView protein in SMART
SM00570 AWS, 1 hit
SM00508 PostSET, 1 hit
SM00317 SET, 1 hit
SM00456 WW, 1 hit
SUPFAMiSSF47676 SSF47676, 1 hit
SSF51045 SSF51045, 1 hit
PROSITEiView protein in PROSITE
PS51215 AWS, 1 hit
PS50868 POST_SET, 1 hit
PS51568 SAM_MT43_SET2_1, 1 hit
PS50280 SET, 1 hit
PS51319 TFIIS_N, 1 hit
PS01159 WW_DOMAIN_1, 1 hit
PS50020 WW_DOMAIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

C7YYN9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDDEYTTSK MGEIKLEEGA NGARVKQEGS ASMTTTNDSH DGSRSPTASH
60 70 80 90 100
DGVKSRSESA DTPSSTKPPR LSRKVSQKLA ATREPALFDH LPDVTTESYN
110 120 130 140 150
FFQVIPDCLY GSKHLGSTDN DSLDCECREE WRDGENLACG EDSDCINRAT
160 170 180 190 200
KMECSAEAGN CGGGCQNQRF QRKQYANVSV IKTEKKGFGL RADADLQPND
210 220 230 240 250
FVYEYIGEVI NEPTFRRRML QYDEEGIKHF YFMSLNKSEF VDATKKGNLG
260 270 280 290 300
RFCNHSCNPN CYVDKWVVGD KLRMGIFTLR KIQSGEELVF NYNVDRYGAD
310 320 330 340 350
PQPCYCGEPN CVGFIGGKTQ TERATKLPTA TVEALGIDGG DGWDTSVAKK
360 370 380 390 400
PRKKKPDEDD EEYVNSIQPR NLSEDDARKV MATLMQCKEK WIAVKLLERI
410 420 430 440 450
ERCDDERVIH CVMRMHAYQI LKTALNTFLD DHNLVIQILT ILDKFPRLTR
460 470 480 490 500
NKIQDSKIEA TVEGLTHSDH EDVATRSKKL LDEWSKLEVG YRIRRRKFDP
510 520 530 540 550
NAPTANSFEE RRGAGREDEA AQSTSKTTSP FNNVEVPKGP RNSVPQRNNA
560 570 580 590 600
FFHNGGRPRR APFNAPLPRG WFTAKDAAGN TYFYNKQGVT TWQKPTQPAG
610 620 630 640 650
ESVAKAPSKA MKEQLAIQSI IDQVTEKGTP KHPTVSTPKA AETPTKEPKP
660 670 680 690 700
EKWRSLPIEK QMKIYENTLF PHIKHVLDKF HHKLPKEELK RLGKDIAKKL
710 720 730 740 750
VASDYKNNRV GDPSSPLSDK QAKKMRKFVN DFLDRAVEKY GEHQKRKAAR
760 770 780 790 800
ASQKETNDGE GLDERADRNG GSAADRPAGS SHAKDDVPMA DELDEAALSD
810 820 830 840 850
NDGPRSSTSP DRKRKREVEV EASGSPSLAS SEGPTVKRVR EDEMDEPSPP
860 870 880 890 900
PPPPPPPQSA MENVMTAEQQ ALREQEEALV RENEEAQRLE DEANRTKCTE
910 920
DATRGAEKDA PLASNEPSQL SHEAQGSA
Length:928
Mass (Da):103,862
Last modified:October 13, 2009 - v1
Checksum:i244E381A3CA29ECE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG698903 Genomic DNA Translation: EEU43223.1
RefSeqiXP_003048936.1, XM_003048890.1

Genome annotation databases

EnsemblFungiiNechaT106311; NechaP106311; NechaG106311
GeneIDi9665522
KEGGinhe:NECHADRAFT_106311

Similar proteinsi

Entry informationi

Entry nameiC7YYN9_NECH7
AccessioniPrimary (citable) accession number: C7YYN9
Entry historyiIntegrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: March 28, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported