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C7YYG9 (DAPB_NECH7) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable dipeptidyl-aminopeptidase B

Short name=DPAP B
EC=3.4.14.5
Gene names
Name:DAPB
ORF Names:NECHADRAFT_47100
OrganismNectria haematococca (strain 77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVI) (Fusarium solani subsp. pisi) [Reference proteome]
Taxonomic identifier660122 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeHypocrealesNectriaceaeFusariumFusarium solani species complex

Protein attributes

Sequence length912 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline By similarity.

Catalytic activity

Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline.

Subcellular location

Vacuole membrane; Single-pass type II membrane protein By similarity. Note: Lysosome-like vacuoles By similarity.

Sequence similarities

Belongs to the peptidase S9B family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 912912Probable dipeptidyl-aminopeptidase B
PRO_0000412150

Regions

Topological domain1 – 8585Cytoplasmic Potential
Transmembrane86 – 10621Helical; Signal-anchor for type II membrane protein; Potential
Topological domain107 – 912806Vacuolar Potential

Sites

Active site7491Charge relay system By similarity
Active site8261Charge relay system By similarity
Active site8591Charge relay system By similarity

Amino acid modifications

Glycosylation3441N-linked (GlcNAc...) Potential
Glycosylation8081N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
C7YYG9 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: 316574CA966658A3

FASTA912102,536
        10         20         30         40         50         60 
MSSALSPEGD RRYSDDSLSS VSTTSLVFER IQEKTEMDAD NDKEKDPRAL DDEDPLRDED 

        70         80         90        100        110        120 
DLETGPFLGP GASLHREPMD RGLRRILIIV AVVFIGGWLA GLGIFIASGS YHHESDTEHD 

       130        140        150        160        170        180 
PDANSRGSGK SLSMDQLFDG TWSPKYHSIS WIAGPKGEDG LLLEVGASNK PYIVVEDIRS 

       190        200        210        220        230        240 
DKNVATRDDA EPKASNSRTL MEHPYFEYDG KQYSPSWSEP SPDLTKVLLG VDRKKNWRHS 

       250        260        270        280        290        300 
FSAIYFVLDV KTQEAEPLVP DQVDARIQLA SWSPKSDAVS FTRENNLYIR RLTGDKDVTQ 

       310        320        330        340        350        360 
ITKDGGPEYF YGIPDWVYEE EVFSGRSATW WSDDGKYLAF LRTNETGVPE YPVQFFIERP 

       370        380        390        400        410        420 
SGTTPEDGEE AYPEVEQIKY PKAGAHNPVV DLQFYDIGKK DTFSVEIDGA FADDDRIINN 

       430        440        450        460        470        480 
LLWAGDKAIV KQTNRVSDVL KVVLVDVPSR KGKTINTINI NEIDGGWFEI SHKMTYIPAD 

       490        500        510        520        530        540 
PKNGREHDGY VDSVIHEGYD HLAYFTPLDN SEPIMLTKGN WEVDDAPSAV DLANNLVYFI 

       550        560        570        580        590        600 
AAKESSIQRH VYSVKLDGSD LQALTDPKTE AYYDASFSKG AGFVFLSYRG PKVPTQKVIS 

       610        620        630        640        650        660 
TPVSASSYER IIEDNAELAD RARRHELPIL KYGTLDLDTG VKVNYVERRP PHFDAKKQYP 

       670        680        690        700        710        720 
VLFHQYSGPG SQSVTKRFAV DFQAYVAAAL GYLVITVDPR GTGFLGRKHR VTVRSKLGVH 

       730        740        750        760        770        780 
EAHDHIAAAA SFASRPYVDA ERLAIWGWSY GGFTTLKTLE QDAGRTFSYG MAVAPVTDWR 

       790        800        810        820        830        840 
FYDSIYTERY MRTPQDNPDG YDLSKVANAT ALGENKRFLL MHGVADDNVH FQNSLTLLDD 

       850        860        870        880        890        900 
LDLAGVENYD VHVFPDSDHS IYFHNGNRIV YDKLRNWLIN AFNGEWLKVS NPQPQKDPVE 

       910 
KEKRHMVPQA LV 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
GG698903 Genomic DNA. Translation: EEU43005.1.
RefSeqXP_003048718.1. XM_003048672.1.

3D structure databases

ProteinModelPortalC7YYG9.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiNechaT47100; NechaP47100; NechaG47100.
GeneID9665490.
KEGGnhe:NECHADRAFT_47100.

Phylogenomic databases

KOK01282.
OrthoDBEOG72VHFG.

Family and domain databases

Gene3D2.140.10.30. 1 hit.
3.40.50.1820. 1 hit.
InterProIPR029058. AB_hydrolase.
IPR001375. Peptidase_S9.
IPR002469. Peptidase_S9B.
[Graphical view]
PfamPF00930. DPPIV_N. 1 hit.
PF00326. Peptidase_S9. 1 hit.
[Graphical view]
SUPFAMSSF53474. SSF53474. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDAPB_NECH7
AccessionPrimary (citable) accession number: C7YYG9
Entry history
Integrated into UniProtKB/Swiss-Prot: July 27, 2011
Last sequence update: October 13, 2009
Last modified: June 11, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries