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C7YU48 (C7YU48_NECH7) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length203 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity By similarity. RuleBase RU004203

Catalytic activity

Cleavage of peptide bonds with very broad specificity. RuleBase RU000694

Subunit structure

The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits By similarity.

Subcellular location

Cytoplasm. Nucleus By similarity SAAS SAAS016050 RuleBase RU000694.

Sequence similarities

Belongs to the peptidase T1B family. RuleBase RU004202

Sequences

Sequence LengthMass (Da)Tools
C7YU48 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: 0788854AB834A2FC

FASTA20322,308
        10         20         30         40         50         60 
MEVLLGITGK DFTIIAASKA AMRGATILKA SDDKTRALNK HTLLAFSGEA GDTVQFAEYI 

        70         80         90        100        110        120 
QRNAQLYSMR NESDLSPSGL AHFVRGELAT SLRSRKPYNV NLLMGGVDPI TGKPSLYWLD 

       130        140        150        160        170        180 
YLASLADVPY AAHGYAQYYC LSILDKHHHP DITLGQGIKI LTMCTDELKR RLPIDFKGMV 

       190        200 
VKAVKADGIV DIEFDDDKVV KSA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
GG698900 Genomic DNA. Translation: EEU44740.1.
RefSeqXP_003050453.1. XM_003050407.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiNechaT71878; NechaP71878; NechaG71878.
GeneID9665426.
KEGGnhe:NECHADRAFT_71878.

Phylogenomic databases

KOK02734.
OrthoDBEOG7SJDGT.

Family and domain databases

Gene3D3.60.20.10. 1 hit.
InterProIPR029055. Ntn_hydrolases_N.
IPR016050. Proteasome_bsu_CS.
IPR001353. Proteasome_sua/b.
IPR023333. Proteasome_suB-type.
[Graphical view]
PfamPF00227. Proteasome. 1 hit.
[Graphical view]
SUPFAMSSF56235. SSF56235. 1 hit.
PROSITEPS00854. PROTEASOME_BETA_1. 1 hit.
PS51476. PROTEASOME_BETA_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC7YU48_NECH7
AccessionPrimary (citable) accession number: C7YU48
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: June 11, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)