C7YU48 (C7YU48_NECH7) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Proteasome subunit beta type RuleBase RU004203
EC=3.4.25.1 RuleBase RU004203

Gene names

ORF Names:

NECHADRAFT_71878 EMBL EEU44740.1

Organism

Nectria haematococca (strain 77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVI) (Fusarium solani subsp. pisi) [Reference proteome]

Taxonomic identifier

660122 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › sordariomyceta › Sordariomycetes › Hypocreomycetidae › Hypocreales › Nectriaceae › Nectria › Nectria haematococca complex › Nectria haematococca › Fusarium solani subsp. pisi

Protein attributes

Sequence length	203 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity By similarity. RuleBase RU004203
Catalytic activity	Cleavage of peptide bonds with very broad specificity. RuleBase RU000694
Subunit structure	The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits By similarity.
Subcellular location	Cytoplasm. Nucleus By similarity RuleBase RU000694.
Sequence similarities	Belongs to the peptidase T1B family. RuleBase RU004202

Ontologies

Keywords
Cellular component	Nucleus SAAS SAAS016050 Proteasome RuleBase RU000694
Molecular function	Hydrolase Protease Threonine protease RuleBase RU000694
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	proteolysis involved in cellular protein catabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell proteasome core complex Inferred from electronic annotation. Source: InterPro
Molecular_function	threonine-type endopeptidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C7YU48 [UniParc]. Last modified October 13, 2009. Version 1. Checksum: 0788854AB834A2FC	FASTA	203	22,308
	10 20 30 40 50 60 MEVLLGITGK DFTIIAASKA AMRGATILKA SDDKTRALNK HTLLAFSGEA GDTVQFAEYI 70 80 90 100 110 120 QRNAQLYSMR NESDLSPSGL AHFVRGELAT SLRSRKPYNV NLLMGGVDPI TGKPSLYWLD 130 140 150 160 170 180 YLASLADVPY AAHGYAQYYC LSILDKHHHP DITLGQGIKI LTMCTDELKR RLPIDFKGMV 190 200 VKAVKADGIV DIEFDDDKVV KSA

References

[1]

"The genome of Nectria haematococca: contribution of supernumerary chromosomes to gene expansion." Coleman J.J., Rounsley S.D., Rodriguez-Carres M., Kuo A., Wasmann C.C., Grimwood J., Schmutz J., Taga M., White G.J., Zhou S., Schwartz D.C., Freitag M., Ma L.-J., Danchin E.G.J., Henrissat B., Coutinho P.M., Nelson D.R., Straney D. , Napoli C.A., Barker B.M., Gribskov M., Rep M., Kroken S., Molnar I., Rensing C., Kennell J.C., Zamora J., Farman M.L., Selker E.U., Salamov A., Shapiro H., Pangilinan J., Lindquist E., Lamers C., Grigoriev I.V., Geiser D.M., Covert S.F., Temporini E., VanEtten H.D. PLoS Genet. 5:E1000618-E1000618(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVI.

Cross-references

Sequence databases
EMBL GenBank DDBJ	GG698900 Genomic DNA. Translation: EEU44740.1.
RefSeq	XP_003050453.1. XM_003050407.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	NechaT71878; NechaP71878; NechaG71878.
GeneID	9665426.
KEGG	nhe:NECHADRAFT_71878.
Phylogenomic databases
KO	K02734.
OrthoDB	EOG4TB7MP.
Family and domain databases
InterPro	IPR016050. Proteasome_bsu_CS. IPR001353. Proteasome_sua/b. IPR023333. Proteasome_suB-type. [Graphical view]
Pfam	PF00227. Proteasome. 1 hit. [Graphical view]
PROSITE	PS00854. PROTEASOME_B_1. 1 hit. PS51476. PROTEASOME_B_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C7YU48_NECH7

Accession

Primary (citable) accession number: C7YU48

Entry history

Integrated into UniProtKB/TrEMBL:	October 13, 2009
Last sequence update:	October 13, 2009
Last modified:	June 13, 2012
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)