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C7YTG9

- C7YTG9_NECH7

UniProt

C7YTG9 - C7YTG9_NECH7

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Protein
Histone-lysine N-methyltransferase, H3 lysine-4 specific
Gene
SDG2101, NECHADRAFT_49470
Organism
Nectria haematococca (strain 77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVI) (Fusarium solani subsp. pisi)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation By similarity.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].UniRule annotationSAAS annotations

GO - Molecular functioni

  1. histone-lysine N-methyltransferase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Chromatin regulatorUniRule annotation, MethyltransferaseUniRule annotationSAAS annotationsImported, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineUniRule annotationSAAS annotations

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferase, H3 lysine-4 specificUniRule annotation (EC:2.1.1.43UniRule annotation)
Gene namesi
Name:SDG2101Imported
ORF Names:NECHADRAFT_49470Imported
OrganismiNectria haematococca (strain 77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVI) (Fusarium solani subsp. pisi)
Taxonomic identifieri660122 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeHypocrealesNectriaceaeFusariumFusarium solani species complex
ProteomesiUP000005206: Unassembled WGS sequence

Subcellular locationi

Nucleus By similarity UniRule annotation

GO - Cellular componenti

  1. Set1C/COMPASS complex Source: InterPro
  2. chromosome Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

ChromosomeUniRule annotation, NucleusUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Component of the COMPASS (Set1C) complex By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains SET domain.SAAS annotations
Contains post-SET domain.SAAS annotations

Phylogenomic databases

KOiK11422.
OrthoDBiEOG7P8PH3.

Family and domain databases

InterProiIPR024657. COMPASS_Set1_N-SET.
IPR017111. Hist_H3-K4_MeTrfase_1_fun.
IPR003616. Post-SET_dom.
IPR024636. SET_assoc.
IPR001214. SET_dom.
[Graphical view]
PfamiPF11764. N-SET. 1 hit.
PF00856. SET. 1 hit.
PF11767. SET_assoc. 1 hit.
[Graphical view]
PIRSFiPIRSF037104. Histone_H3-K4_mtfrase_Set1_fun. 1 hit.
SMARTiSM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS50868. POST_SET. 1 hit.
PS51572. SAM_MT43_1. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C7YTG9-1 [UniParc]FASTAAdd to Basket

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MTRPPGASFA QFFPTAPKVK AQAQSRADRD RDRDRPKTTS SSASINGGAS     50
DPTPASAGFD AHANASAQPA PGPNGHLAVS DTLSAHPDDN GSPLADIPST 100
VDSASSYSSA ASSIFSTSAR HGAAATATSS RLPTSSLTPI ASKDSPSNSS 150
ATAPTKPDMS ASLAADRAAR QSSHNSPAVG PNGSISDGPL AIERPPARDP 200
MPSVKGLKCT YDPLLDRVHN KSVSRNAKPT YKEFGRDDDA PPTDPRLSKP 250
GGRLGYINTD YYLPKARLRP APENIKPYPY DPKTSIGPGP PTQIVVTRYN 300
PLVPFSKVTA IFATFGEIAE SSNKMHPETG SYLGFATIRY RDSKRPDRPR 350
VSAIDAARRA VRTRGIKVDA DVVRVDYDPE GRRSRRMLEE HLRREKERME 400
KKEKERLAQA VQAPPIGPKS TPASNFTRPP PTAPKGPAAQ RPAGAPSTPQ 450
PTTTPVQPKG HAAVEVKNLA SQLTDDPYIY IAGDSVPVLT SIVPHMKKRL 500
KNYGFEDIRL DKSGYYIVFR NSFTGKSEAE RCFRAVNHTE FFNYDMTMQL 550
CLPRPRRSDE SPERRRQASA SPDRKPRGET GQRDEKDRRR REEEADLEEE 600
KKQRAKNFDP VIEAVEVVRR EMTEHLIRHI RTKVAAPFLS EFLDPANHVA 650
KRRKLNIEHP DDIEEIPSIE DGNDSSRVGT PNSRADPIER RTGRLEPKAL 700
PRIRKTKVKG QAQRSAFIDP FARQRPVARN AFRSLHHRLR SLDSDVESDD 750
DTDTRALLAR ETEEPESRPR SRMSTDDEAS KDDFASWGPG EDDSMTEASF 800
HITDPLISRK RKLDASVETA FKRQKKSDEE LFGVKLGQLG TGFVAREDSV 850
DIIPEPETGD DLESRVSRSE TPASVIGKTL KKKPAKAKKK TKKAVFEERE 900
ALKRQAETDS QRGDEDEVVE APKAEPKVEE KPPVAEPVPE PVVEKYDEKL 950
LSTEPLTPAL VLPDGFKPDL SLFQGLALGV NDKPDVAKLS KRFAVKDIGD 1000
PELWLWKRNR IRELNSTKGT LEKPVSIEGY YVPNPTGCAR TEGVKKILNS 1050
EKSKYLPHHI KVQKARQERE ARFKKSGKDA AAAAAEAAKL AAEKLIAKGN 1100
SRANRATNRR YVADLNDQKK TLGQDSDVFK FNQLKKRKKP VKFARSAIHN 1150
WGLYAMENIA KDDMIIEYVG EEVRQQIAEI RENRYLKSGI GSSYLFRIDE 1200
NTVIDATKKG GIARFINHSC MPNCTAKIIK VEGSKRIVIY ALRDIAMNEE 1250
LTYDYKFERE IGSLDRIPCL CGTAACKGFL N 1281
Length:1,281
Mass (Da):142,018
Last modified:October 13, 2009 - v1
Checksum:i82B0188A5F8DC822
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
GG698900 Genomic DNA. Translation: EEU44617.1.
RefSeqiXP_003050330.1. XM_003050284.1.

Genome annotation databases

EnsemblFungiiNechaT49470; NechaP49470; NechaG49470.
GeneIDi9665737.
KEGGinhe:NECHADRAFT_49470.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
GG698900 Genomic DNA. Translation: EEU44617.1 .
RefSeqi XP_003050330.1. XM_003050284.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii NechaT49470 ; NechaP49470 ; NechaG49470 .
GeneIDi 9665737.
KEGGi nhe:NECHADRAFT_49470.

Phylogenomic databases

KOi K11422.
OrthoDBi EOG7P8PH3.

Family and domain databases

InterProi IPR024657. COMPASS_Set1_N-SET.
IPR017111. Hist_H3-K4_MeTrfase_1_fun.
IPR003616. Post-SET_dom.
IPR024636. SET_assoc.
IPR001214. SET_dom.
[Graphical view ]
Pfami PF11764. N-SET. 1 hit.
PF00856. SET. 1 hit.
PF11767. SET_assoc. 1 hit.
[Graphical view ]
PIRSFi PIRSF037104. Histone_H3-K4_mtfrase_Set1_fun. 1 hit.
SMARTi SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view ]
PROSITEi PS50868. POST_SET. 1 hit.
PS51572. SAM_MT43_1. 1 hit.
PS50280. SET. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVI.

Entry informationi

Entry nameiC7YTG9_NECH7
AccessioniPrimary (citable) accession number: C7YTG9
Entry historyi
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: May 14, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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