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C7YTG9 (C7YTG9_NECH7) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length1281 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation By similarity. PIRNR PIRNR037104

Catalytic activity

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. PIRNR PIRNR037104 SAAS SAAS001214

Subunit structure

Component of the COMPASS (Set1C) complex By similarity. PIRNR PIRNR037104

Subcellular location

Nucleus By similarity PIRNR PIRNR037104.

Sequence similarities

Contains 1 SET domain. RuleBase RU004538

Contains SET domain. SAAS SAAS001214

Contains post-SET domain. SAAS SAAS001214

Sequences

Sequence LengthMass (Da)Tools
C7YTG9 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: 82B0188A5F8DC822

FASTA1,281142,018
        10         20         30         40         50         60 
MTRPPGASFA QFFPTAPKVK AQAQSRADRD RDRDRPKTTS SSASINGGAS DPTPASAGFD 

        70         80         90        100        110        120 
AHANASAQPA PGPNGHLAVS DTLSAHPDDN GSPLADIPST VDSASSYSSA ASSIFSTSAR 

       130        140        150        160        170        180 
HGAAATATSS RLPTSSLTPI ASKDSPSNSS ATAPTKPDMS ASLAADRAAR QSSHNSPAVG 

       190        200        210        220        230        240 
PNGSISDGPL AIERPPARDP MPSVKGLKCT YDPLLDRVHN KSVSRNAKPT YKEFGRDDDA 

       250        260        270        280        290        300 
PPTDPRLSKP GGRLGYINTD YYLPKARLRP APENIKPYPY DPKTSIGPGP PTQIVVTRYN 

       310        320        330        340        350        360 
PLVPFSKVTA IFATFGEIAE SSNKMHPETG SYLGFATIRY RDSKRPDRPR VSAIDAARRA 

       370        380        390        400        410        420 
VRTRGIKVDA DVVRVDYDPE GRRSRRMLEE HLRREKERME KKEKERLAQA VQAPPIGPKS 

       430        440        450        460        470        480 
TPASNFTRPP PTAPKGPAAQ RPAGAPSTPQ PTTTPVQPKG HAAVEVKNLA SQLTDDPYIY 

       490        500        510        520        530        540 
IAGDSVPVLT SIVPHMKKRL KNYGFEDIRL DKSGYYIVFR NSFTGKSEAE RCFRAVNHTE 

       550        560        570        580        590        600 
FFNYDMTMQL CLPRPRRSDE SPERRRQASA SPDRKPRGET GQRDEKDRRR REEEADLEEE 

       610        620        630        640        650        660 
KKQRAKNFDP VIEAVEVVRR EMTEHLIRHI RTKVAAPFLS EFLDPANHVA KRRKLNIEHP 

       670        680        690        700        710        720 
DDIEEIPSIE DGNDSSRVGT PNSRADPIER RTGRLEPKAL PRIRKTKVKG QAQRSAFIDP 

       730        740        750        760        770        780 
FARQRPVARN AFRSLHHRLR SLDSDVESDD DTDTRALLAR ETEEPESRPR SRMSTDDEAS 

       790        800        810        820        830        840 
KDDFASWGPG EDDSMTEASF HITDPLISRK RKLDASVETA FKRQKKSDEE LFGVKLGQLG 

       850        860        870        880        890        900 
TGFVAREDSV DIIPEPETGD DLESRVSRSE TPASVIGKTL KKKPAKAKKK TKKAVFEERE 

       910        920        930        940        950        960 
ALKRQAETDS QRGDEDEVVE APKAEPKVEE KPPVAEPVPE PVVEKYDEKL LSTEPLTPAL 

       970        980        990       1000       1010       1020 
VLPDGFKPDL SLFQGLALGV NDKPDVAKLS KRFAVKDIGD PELWLWKRNR IRELNSTKGT 

      1030       1040       1050       1060       1070       1080 
LEKPVSIEGY YVPNPTGCAR TEGVKKILNS EKSKYLPHHI KVQKARQERE ARFKKSGKDA 

      1090       1100       1110       1120       1130       1140 
AAAAAEAAKL AAEKLIAKGN SRANRATNRR YVADLNDQKK TLGQDSDVFK FNQLKKRKKP 

      1150       1160       1170       1180       1190       1200 
VKFARSAIHN WGLYAMENIA KDDMIIEYVG EEVRQQIAEI RENRYLKSGI GSSYLFRIDE 

      1210       1220       1230       1240       1250       1260 
NTVIDATKKG GIARFINHSC MPNCTAKIIK VEGSKRIVIY ALRDIAMNEE LTYDYKFERE 

      1270       1280 
IGSLDRIPCL CGTAACKGFL N 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
GG698900 Genomic DNA. Translation: EEU44617.1.
RefSeqXP_003050330.1. XM_003050284.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiNechaT49470; NechaP49470; NechaG49470.
GeneID9665737.
KEGGnhe:NECHADRAFT_49470.

Phylogenomic databases

KOK11422.
OrthoDBEOG7P8PH3.

Family and domain databases

InterProIPR024657. COMPASS_Set1_N-SET.
IPR017111. Hist_H3-K4_MeTrfase_1_fun.
IPR015722. Histone-lysine_MeTfrase.
IPR003616. Post-SET_dom.
IPR024636. SET_assoc.
IPR001214. SET_dom.
[Graphical view]
PANTHERPTHR22884:SF10. PTHR22884:SF10. 1 hit.
PfamPF11764. N-SET. 1 hit.
PF00856. SET. 1 hit.
PF11767. SET_assoc. 1 hit.
[Graphical view]
PIRSFPIRSF037104. Histone_H3-K4_mtfrase_Set1_fun. 1 hit.
SMARTSM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEPS50868. POST_SET. 1 hit.
PS51572. SAM_MT43_1. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC7YTG9_NECH7
AccessionPrimary (citable) accession number: C7YTG9
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: April 16, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)