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C7YTG9

- C7YTG9_NECH7

UniProt

C7YTG9 - C7YTG9_NECH7

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Protein

Histone-lysine N-methyltransferase, H3 lysine-4 specific

Gene

SDG2101

Organism
Nectria haematococca (strain 77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVI) (Fusarium solani subsp. pisi)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].UniRule annotationSAAS annotation

GO - Molecular functioni

  1. histone-lysine N-methyltransferase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Chromatin regulatorUniRule annotation, MethyltransferaseUniRule annotation, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferase, H3 lysine-4 specificUniRule annotation (EC:2.1.1.43UniRule annotation)
Gene namesi
Name:SDG2101Imported
ORF Names:NECHADRAFT_49470Imported
OrganismiNectria haematococca (strain 77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVI) (Fusarium solani subsp. pisi)Imported
Taxonomic identifieri660122 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeHypocrealesNectriaceaeFusariumFusarium solani species complex
ProteomesiUP000005206: Unassembled WGS sequence

Subcellular locationi

Nucleus UniRule annotation

GO - Cellular componenti

  1. chromosome Source: UniProtKB-KW
  2. Set1C/COMPASS complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

ChromosomeUniRule annotation, NucleusUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Component of the COMPASS (Set1C) complex.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains SET domain.SAAS annotation
Contains post-SET domain.SAAS annotation

Phylogenomic databases

InParanoidiC7YTG9.
KOiK11422.
OrthoDBiEOG7P8PH3.

Family and domain databases

InterProiIPR024657. COMPASS_Set1_N-SET.
IPR017111. Hist_H3-K4_MeTrfase_1_fun.
IPR003616. Post-SET_dom.
IPR024636. SET_assoc.
IPR001214. SET_dom.
[Graphical view]
PfamiPF11764. N-SET. 1 hit.
PF00856. SET. 1 hit.
PF11767. SET_assoc. 1 hit.
[Graphical view]
PIRSFiPIRSF037104. Histone_H3-K4_mtfrase_Set1_fun. 1 hit.
SMARTiSM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS50868. POST_SET. 1 hit.
PS51572. SAM_MT43_1. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C7YTG9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTRPPGASFA QFFPTAPKVK AQAQSRADRD RDRDRPKTTS SSASINGGAS
60 70 80 90 100
DPTPASAGFD AHANASAQPA PGPNGHLAVS DTLSAHPDDN GSPLADIPST
110 120 130 140 150
VDSASSYSSA ASSIFSTSAR HGAAATATSS RLPTSSLTPI ASKDSPSNSS
160 170 180 190 200
ATAPTKPDMS ASLAADRAAR QSSHNSPAVG PNGSISDGPL AIERPPARDP
210 220 230 240 250
MPSVKGLKCT YDPLLDRVHN KSVSRNAKPT YKEFGRDDDA PPTDPRLSKP
260 270 280 290 300
GGRLGYINTD YYLPKARLRP APENIKPYPY DPKTSIGPGP PTQIVVTRYN
310 320 330 340 350
PLVPFSKVTA IFATFGEIAE SSNKMHPETG SYLGFATIRY RDSKRPDRPR
360 370 380 390 400
VSAIDAARRA VRTRGIKVDA DVVRVDYDPE GRRSRRMLEE HLRREKERME
410 420 430 440 450
KKEKERLAQA VQAPPIGPKS TPASNFTRPP PTAPKGPAAQ RPAGAPSTPQ
460 470 480 490 500
PTTTPVQPKG HAAVEVKNLA SQLTDDPYIY IAGDSVPVLT SIVPHMKKRL
510 520 530 540 550
KNYGFEDIRL DKSGYYIVFR NSFTGKSEAE RCFRAVNHTE FFNYDMTMQL
560 570 580 590 600
CLPRPRRSDE SPERRRQASA SPDRKPRGET GQRDEKDRRR REEEADLEEE
610 620 630 640 650
KKQRAKNFDP VIEAVEVVRR EMTEHLIRHI RTKVAAPFLS EFLDPANHVA
660 670 680 690 700
KRRKLNIEHP DDIEEIPSIE DGNDSSRVGT PNSRADPIER RTGRLEPKAL
710 720 730 740 750
PRIRKTKVKG QAQRSAFIDP FARQRPVARN AFRSLHHRLR SLDSDVESDD
760 770 780 790 800
DTDTRALLAR ETEEPESRPR SRMSTDDEAS KDDFASWGPG EDDSMTEASF
810 820 830 840 850
HITDPLISRK RKLDASVETA FKRQKKSDEE LFGVKLGQLG TGFVAREDSV
860 870 880 890 900
DIIPEPETGD DLESRVSRSE TPASVIGKTL KKKPAKAKKK TKKAVFEERE
910 920 930 940 950
ALKRQAETDS QRGDEDEVVE APKAEPKVEE KPPVAEPVPE PVVEKYDEKL
960 970 980 990 1000
LSTEPLTPAL VLPDGFKPDL SLFQGLALGV NDKPDVAKLS KRFAVKDIGD
1010 1020 1030 1040 1050
PELWLWKRNR IRELNSTKGT LEKPVSIEGY YVPNPTGCAR TEGVKKILNS
1060 1070 1080 1090 1100
EKSKYLPHHI KVQKARQERE ARFKKSGKDA AAAAAEAAKL AAEKLIAKGN
1110 1120 1130 1140 1150
SRANRATNRR YVADLNDQKK TLGQDSDVFK FNQLKKRKKP VKFARSAIHN
1160 1170 1180 1190 1200
WGLYAMENIA KDDMIIEYVG EEVRQQIAEI RENRYLKSGI GSSYLFRIDE
1210 1220 1230 1240 1250
NTVIDATKKG GIARFINHSC MPNCTAKIIK VEGSKRIVIY ALRDIAMNEE
1260 1270 1280
LTYDYKFERE IGSLDRIPCL CGTAACKGFL N
Length:1,281
Mass (Da):142,018
Last modified:October 13, 2009 - v1
Checksum:i82B0188A5F8DC822
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
GG698900 Genomic DNA. Translation: EEU44617.1.
RefSeqiXP_003050330.1. XM_003050284.1.

Genome annotation databases

EnsemblFungiiNechaT49470; NechaP49470; NechaG49470.
GeneIDi9665737.
KEGGinhe:NECHADRAFT_49470.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
GG698900 Genomic DNA. Translation: EEU44617.1 .
RefSeqi XP_003050330.1. XM_003050284.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii NechaT49470 ; NechaP49470 ; NechaG49470 .
GeneIDi 9665737.
KEGGi nhe:NECHADRAFT_49470.

Phylogenomic databases

InParanoidi C7YTG9.
KOi K11422.
OrthoDBi EOG7P8PH3.

Family and domain databases

InterProi IPR024657. COMPASS_Set1_N-SET.
IPR017111. Hist_H3-K4_MeTrfase_1_fun.
IPR003616. Post-SET_dom.
IPR024636. SET_assoc.
IPR001214. SET_dom.
[Graphical view ]
Pfami PF11764. N-SET. 1 hit.
PF00856. SET. 1 hit.
PF11767. SET_assoc. 1 hit.
[Graphical view ]
PIRSFi PIRSF037104. Histone_H3-K4_mtfrase_Set1_fun. 1 hit.
SMARTi SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view ]
PROSITEi PS50868. POST_SET. 1 hit.
PS51572. SAM_MT43_1. 1 hit.
PS50280. SET. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVIImported.

Entry informationi

Entry nameiC7YTG9_NECH7
AccessioniPrimary (citable) accession number: C7YTG9
Entry historyi
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: October 29, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3