ID   C7YHN6_FUSV7            Unreviewed;       839 AA.
AC   C7YHN6;
DT   13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT   13-OCT-2009, sequence version 1.
DT   27-MAR-2024, entry version 65.
DE   RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
GN   ORFNames=NECHADRAFT_90203 {ECO:0000313|EMBL:EEU48669.1};
OS   Fusarium vanettenii (strain ATCC MYA-4622 / CBS 123669 / FGSC 9596 / NRRL
OS   45880 / 77-13-4) (Fusarium solani subsp. pisi).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium solani species complex; Fusarium vanettenii.
OX   NCBI_TaxID=660122 {ECO:0000313|EMBL:EEU48669.1, ECO:0000313|Proteomes:UP000005206};
RN   [1] {ECO:0000313|EMBL:EEU48669.1, ECO:0000313|Proteomes:UP000005206}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4622 / CBS 123669 / FGSC 9596 / NRRL 45880 / 77-13-4
RC   {ECO:0000313|Proteomes:UP000005206};
RX   PubMed=19714214; DOI=10.1371/journal.pgen.1000618;
RA   Coleman J.J., Rounsley S.D., Rodriguez-Carres M., Kuo A., Wasmann C.C.,
RA   Grimwood J., Schmutz J., Taga M., White G.J., Zhou S., Schwartz D.C.,
RA   Freitag M., Ma L.J., Danchin E.G., Henrissat B., Coutinho P.M.,
RA   Nelson D.R., Straney D., Napoli C.A., Barker B.M., Gribskov M., Rep M.,
RA   Kroken S., Molnar I., Rensing C., Kennell J.C., Zamora J., Farman M.L.,
RA   Selker E.U., Salamov A., Shapiro H., Pangilinan J., Lindquist E.,
RA   Lamers C., Grigoriev I.V., Geiser D.M., Covert S.F., Temporini E.,
RA   Vanetten H.D.;
RT   "The genome of Nectria haematococca: contribution of supernumerary
RT   chromosomes to gene expansion.";
RL   PLoS Genet. 5:E1000618-E1000618(2009).
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
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DR   EMBL; GG698896; EEU48669.1; -; Genomic_DNA.
DR   RefSeq; XP_003054382.1; XM_003054336.1.
DR   AlphaFoldDB; C7YHN6; -.
DR   STRING; 660122.C7YHN6; -.
DR   EnsemblFungi; NechaT90203; NechaP90203; NechaG90203.
DR   GeneID; 9674606; -.
DR   KEGG; nhe:NECHADRAFT_90203; -.
DR   VEuPathDB; FungiDB:NECHADRAFT_90203; -.
DR   eggNOG; KOG2166; Eukaryota.
DR   HOGENOM; CLU_004747_7_1_1; -.
DR   InParanoid; C7YHN6; -.
DR   OMA; NVVQSCF; -.
DR   OrthoDB; 5474206at2759; -.
DR   Proteomes; UP000005206; Unassembled WGS sequence.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF168; CULLIN-3; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005206}.
FT   DOMAIN          450..704
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          375..396
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        375..391
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   839 AA;  95869 MW;  5F60B0DB498C57E3 CRC64;
     MISGRGGSGA RTGRIRPPRR IVRPNERDEG GDFEACWNML KEALRDIHQK NCSRLSFEEL
     YRAAYKIVLK KKGEALYDRV KAFEEQWFAD HVIPKIRDLV TTSLINIGVE RTSVTSVNER
     RQTGEKFLKG LRDTWEDHNM SMNMTADILM YLDRGYSHLE AQRVPIFATT IALFRDHILR
     SCLNSNTKDT VIDILISVIL DQIDMEREGD IIDRNLVRSC SRMLSCLYET EEESENDKLY
     LTVFEPRFLA NSKTYYAAEG KKLLRESDAG TWLRHTQQRL NEEIDRCGTT IELETLPKVT
     ETIDQELIVA HMSEFLALEG SGLRWMIDND KIDELSILYR LISRVDSKKT ALKEILQHRV
     VELGLEIEKN LKSTDFSAGH GEGEEGGEGD KSKTLNPAAQ QTAAAVKWVD DVLRLKDKFD
     ALWAQCFQND LIIQSALTKS FSDFINMFSR CSEYVSLFID DNLKRGIKGK TEAEVDVVLE
     KAIVLIRYLQ DRDLFQTYYQ RHLARRLLHA KSESHDVEKQ IISRMKQEMG QQFTSKFEGM
     FRDLATSSDL SSGYRDHIRN VGDGAKVIDL NINVLTTNYW PPEVMGRTAQ IGEGSRVTCE
     YPPEVQRLQA SFEQFYLTNR NGRKLTWIGT TGSADVKCTF PAIPGKSGPL ARERRYEINV
     PTFGMVVLLL FNDLAEGESL SFEEIQAKTN ISTQDLMRTL TAIAVAPKSR VLAKEPLSKS
     VKPTDKFTFN ASFQSKTIRI KAPIINAVSK VEDTSERKKT EEKNNQTRAH IVDAAVVRIM
     KSRKELSHSQ LVSEVLTQLS GRFRPEVSLI KKRIEDLIAR EYLERPDEDG MPSLYRYVA
//