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Protein
Submitted name:

Cathepsin D (Lysosomal aspartyl protease)

Gene

ctsd

Organism
Schistosoma japonicum (Blood fluke)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionAspartyl proteaseUniRule annotation, Hydrolase, Protease

Protein family/group databases

MEROPSiA01.009.

Names & Taxonomyi

Protein namesi
Submitted name:
Cathepsin D (Lysosomal aspartyl protease)Imported (EC:3.4.23.5Imported)
Gene namesi
Name:ctsdImported
OrganismiSchistosoma japonicum (Blood fluke)Imported
Taxonomic identifieri6182 [NCBI]
Taxonomic lineageiEukaryotaMetazoaPlatyhelminthesTrematodaDigeneaStrigeididaSchistosomatoideaSchistosomatidaeSchistosoma

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini66 – 240Peptidase A1InterPro annotationAdd BLAST175

Sequence similaritiesi

Belongs to the peptidase A1 family.PROSITE-ProRule annotationSAAS annotation

Family and domain databases

Gene3Di2.40.70.10. 1 hit.
InterProiView protein in InterPro
IPR001461. Aspartic_peptidase_A1.
IPR001969. Aspartic_peptidase_AS.
IPR012848. Aspartic_peptidase_N.
IPR033121. PEPTIDASE_A1.
IPR021109. Peptidase_aspartic_dom_sf.
PANTHERiPTHR13683. PTHR13683. 1 hit.
PfamiView protein in Pfam
PF07966. A1_Propeptide. 1 hit.
PF00026. Asp. 1 hit.
PRINTSiPR00792. PEPSIN.
SUPFAMiSSF50630. SSF50630. 1 hit.
PROSITEiView protein in PROSITE
PS00141. ASP_PROTEASE. 1 hit.
PS51767. PEPTIDASE_A1. 1 hit.

Sequencei

Sequence statusi: Fragment.

C7TZL5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLHLLLLLHL VSSEVVRVPL YPLKSARRSL IEFETSLENV QKVWFSRFSN
60 70 80 90 100
VEPRPEYLKN YLDAQYYGDI TIGTPPQTFS VVFDTGSSNL WVPSKHCSYF
110 120 130 140 150
DIACLLHRKY DSSKSTTYVP NGTDFSIRYG TGSLSGFLST DSLQLGSLGV
160 170 180 190 200
KGQTFGEATK QPGLVFVMAK FDGILGMAYP SLAVGGVTPV FVNMIKQGVV
210 220 230 240
DSPVFSFYLS RNITNVLGGE LMIGGIDDKY YTGEINYVNL
Length:240
Mass (Da):26,576
Last modified:October 13, 2009 - v1
Checksum:i12AACF91B9A928F5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei240Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN330832 mRNA. Translation: CAX83049.1.

Similar proteinsi

Entry informationi

Entry nameiC7TZL5_SCHJA
AccessioniPrimary (citable) accession number: C7TZL5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: November 22, 2017
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation