C7TC74 (C7TC74_LACRG) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Pyruvate dehydrogenase complex E2 component EMBL BAI41795.1

Submitted name:
Pyruvate dehydrogenase complex E2 component,dihydrolipoyllysine-residue acetyltransferase EMBL CAR87217.1

Gene names

Name:	pdhC EMBL CAR87217.1
Ordered Locus Names:	LGG_01322, LRHM_1268 EMBL BAI41795.1

Organism

Lactobacillus rhamnosus (strain ATCC 53103 / GG) [Complete proteome] [HAMAP]

Taxonomic identifier

568703 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lactobacillus › Lactobacillus rhamnosus

Protein attributes

Sequence length	441 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the 2-oxoacid dehydrogenase family. RuleBase RU003423 Contains 1 lipoyl-binding domain. RuleBase RU000447

Ontologies

Keywords
Domain	Lipoyl SAAS SAAS003016 RuleBase RU000447
Ligand	Pyruvate EMBL CAR87217.1
Molecular function	Acyltransferase RuleBase RU003765 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	transferase activity, transferring acyl groups Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C7TC74 [UniParc]. Last modified October 13, 2009. Version 1. Checksum: F2F39FD03472A93A	FASTA	441	46,808
	10 20 30 40 50 60 MAFEFKLPEL GEGLAEGEIV KWDVKPGDDI KEDDTLLEVQ SDKSVEEIPS PVSGKILKIL 70 80 90 100 110 120 VPEGETATVG EALVDIDAPG HNDTPVASGT AAAPQANTDT AAPAAAPAAA GSVPAITDPN 130 140 150 160 170 180 REILAMPSVR QYAREQGIDI SQVPATGKHG RITKADIDAF KAGAPAAAPA QPAATSAPKA 190 200 210 220 230 240 AQPAPAATPA APKPQPVAPY VSTGSEAELE TREKMTPTRK AIAKAMLASK QRSPHVTSFD 250 260 270 280 290 300 EVEVSKLMAH RKKYKQYAAD KGIKLTFLPY IVKALVTVLR EYPEFNASID DTTDEIVYKH 310 320 330 340 350 360 YFNIGIATNT DHGLYVPVIK NADAKSMFEI AKEISDNAQK AYDSKLKPDE MRGGSMTISN 370 380 390 400 410 420 VGSIGGGWFT PVINQPEVAI LGVGKIAKEP YVNADNEIVV GNLLKLSLSY DHRLIDGALA 430 440 QTALNLMDKL LADPDLLLME G

References

[1]

"Complete genome sequence of the probiotic Lactobacillus rhamnosus ATCC 53103." Morita H., Toh H., Oshima K., Murakami M., Taylor T.D., Igimi S., Hattori M. J. Bacteriol. 191:7630-7631(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 53103 EMBL BAI41795.1 and ATCC 53103 / GG [Tokyo].

[2]

"Comparative genomic analysis of Lactobacillus rhamnosus GG reveals pili containing a human- mucus binding protein." Kankainen M., Paulin L., Tynkkynen S., von Ossowski I., Reunanen J., Partanen P., Satokari R., Vesterlund S., Hendrickx A.P.A., Lebeer S., De Keersmaecker S.C.J., Vanderleyden J., Hamalinen T., Laukkanen S., Salovuori N., Ritari J., Alatalo E., Korpela R. , Mattila-Sandholm T., Lassig A., Hatakka K., Kinnunen K.T., Karjalainen H., Saxelin M., Laakso K., Surakka A., Palva A., SalusjArvi T., Auvinen P., de Vos W.M. Proc. Natl. Acad. Sci. U.S.A. 106:17193-17198(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 53103 / GG [Helsinki].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP011548 Genomic DNA. Translation: BAI41795.1. FM179322 Genomic DNA. Translation: CAR87217.1.
RefSeq	YP_003171068.1. NC_013198.1. YP_005865760.1. NC_017482.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	568703.LGG_01322.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAI41795; BAI41795; LRHM_1268. CAR87217; CAR87217; LGG_01322.
GeneID	12474386. 8422631.
KEGG	lrg:LRHM_1268. lrh:LGG_01322.
PATRIC	22263920. VBILacRha2892_1241.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0508.
HOGENOM	HOG000281564.
KO	K00627.
OMA	VNADNEI.
Enzyme and pathway databases
BioCyc	LRHA568703:GCGS-1311-MONOMER.
Family and domain databases
Gene3D	3.30.559.10. 1 hit. 4.10.320.10. 1 hit.
InterPro	IPR003016. 2-oxoA_DH_lipoyl-BS. IPR001078. 2-oxoacid_DH_actylTfrase. IPR000089. Biotin_lipoyl. IPR023213. CAT-like_dom. IPR004167. E3-bd. IPR011053. Single_hybrid_motif. [Graphical view]
Pfam	PF00198. 2-oxoacid_dh. 1 hit. PF00364. Biotin_lipoyl. 1 hit. PF02817. E3_binding. 1 hit. [Graphical view]
SUPFAM	SSF47005. E3_bd. 1 hit. SSF51230. Hybrid_motif. 1 hit.
PROSITE	PS50968. BIOTINYL_LIPOYL. 1 hit. PS00189. LIPOYL. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C7TC74_LACRG

Accession

Primary (citable) accession number: C7TC74
Secondary accession number(s): C8UTU1

Entry history

Integrated into UniProtKB/TrEMBL:	October 13, 2009
Last sequence update:	October 13, 2009
Last modified:	May 29, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)