Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

C7TBS1 (C7TBS1_LACRG) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Protein attributes

Sequence length197 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. RuleBase RU000544 HAMAP-Rule MF_00124 SAAS SAAS020634

Subunit structure

Homotetramer By similarity. SAAS SAAS020633 HAMAP-Rule MF_00124

Subcellular location

Cytoplasm By similarity SAAS SAAS020633 HAMAP-Rule MF_00124.

Sequence similarities

Belongs to the thymidine kinase family. RuleBase RU004165 HAMAP-Rule MF_00124

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding9 – 168ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding85 – 884ATP By similarity HAMAP-Rule MF_00124

Sites

Active site861Proton acceptor By similarity HAMAP-Rule MF_00124
Metal binding1431Zinc By similarity HAMAP-Rule MF_00124
Metal binding1461Zinc By similarity HAMAP-Rule MF_00124
Metal binding1801Zinc By similarity HAMAP-Rule MF_00124
Metal binding1831Zinc By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
C7TBS1 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: 3F6C5FEE5C8910BB

FASTA19722,617
        10         20         30         40         50         60 
MAQLFFRYGA MNSGKSIEIL KVAHNYEEQN KRVILMTSAV DDRAGVGMIA SRIGLERTAI 

        70         80         90        100        110        120 
PIAHETNLYD VIKTTDPKAA CVLIDEAQFL QKHHIFEAAR VVDELHIPVM AFGLKNDFRN 

       130        140        150        160        170        180 
ELFEGSKYLL LYADKIEEMK TICWFCAKKA IMNLRIHDGK PVYEGEQVLI GGNESYYPVC 

       190 
RHHYFHPPLD RIDQDEE 

« Hide

References

« Hide 'large scale' references
[1]"Complete genome sequence of the probiotic Lactobacillus rhamnosus ATCC 53103."
Morita H., Toh H., Oshima K., Murakami M., Taylor T.D., Igimi S., Hattori M.
J. Bacteriol. 191:7630-7631(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 53103 EMBL BAI41643.1 and ATCC 53103 / GG [Tokyo].
[2]"Comparative genomic analysis of Lactobacillus rhamnosus GG reveals pili containing a human- mucus binding protein."
Kankainen M., Paulin L., Tynkkynen S., von Ossowski I., Reunanen J., Partanen P., Satokari R., Vesterlund S., Hendrickx A.P., Lebeer S., De Keersmaecker S.C., Vanderleyden J., Hamalainen T., Laukkanen S., Salovuori N., Ritari J., Alatalo E., Korpela R. expand/collapse author list , Mattila-Sandholm T., Lassig A., Hatakka K., Kinnunen K.T., Karjalainen H., Saxelin M., Laakso K., Surakka A., Palva A., Salusjarvi T., Auvinen P., de Vos W.M.
Proc. Natl. Acad. Sci. U.S.A. 106:17193-17198(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 53103 / GG [Helsinki].
[3]"Genomic Adaptation of the Lactobacillus casei Group."
Toh H., Oshima K., Nakano A., Takahata M., Murakami M., Takaki T., Nishiyama H., Igimi S., Hattori M., Morita H.
PLoS ONE 8:e75073-e75073(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: ATCC 53103 EMBL BAI41643.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP011548 Genomic DNA. Translation: BAI41643.1.
FM179322 Genomic DNA. Translation: CAR87064.1.
RefSeqYP_003170915.1. NC_013198.1.
YP_005865608.1. NC_017482.1.

3D structure databases

ProteinModelPortalC7TBS1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING568703.LGG_01169.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAI41643; BAI41643; LRHM_1116.
CAR87064; CAR87064; LGG_01169.
GeneID12474234.
8422509.
KEGGlrg:LRHM_1116.
lrh:LGG_01169.
PATRIC22263625. VBILacRha2892_1094.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1435.
HOGENOMHOG000076391.
KOK00857.
OMARTICHCG.
OrthoDBEOG69D3J2.
ProtClustDBCLSK2544169.

Enzyme and pathway databases

BioCycLRHA568703:GCGS-1159-MONOMER.

Family and domain databases

HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC7TBS1_LACRG
AccessionPrimary (citable) accession number: C7TBS1
Secondary accession number(s): C8UTD9
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: April 16, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)