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C7S316

- C7S316_HUMAN

UniProt

C7S316 - C7S316_HUMAN

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Protein
Submitted name:

Potassium voltage-gated channel Isk-related family member 1

Gene

KCNE1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. voltage-gated potassium channel activity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Potassium voltage-gated channel Isk-related family member 1Imported
Gene namesi
Name:KCNE1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA211.

Expressioni

Gene expression databases

ExpressionAtlasiC7S316. baseline.

Structurei

3D structure databases

ProteinModelPortaliC7S316.
SMRiC7S316. Positions 1-129.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

KOiK04894.
OMAiSYRACYV.
PhylomeDBiC7S316.

Family and domain databases

InterProiIPR000369. K_chnl_volt-dep_bsu_KCNE.
IPR005424. K_chnl_volt-dep_bsu_KCNE1.
[Graphical view]
PANTHERiPTHR17028. PTHR17028. 1 hit.
PfamiPF02060. ISK_Channel. 1 hit.
[Graphical view]
PRINTSiPR01604. KCNE1CHANNEL.
PR00168. KCNECHANNEL.

Sequencei

Sequence statusi: Complete.

C7S316-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MILSNTTAVT PFLTKLWQET VQQGGNMSGL ARRSPRSSDG KLEALYVLMV
60 70 80 90 100
LGFFGFFTLG IMLSYIRSKK LEHSNDPFNV YIESDAWQEK DKAYVQARVL
110 120
ESYRSCYVVE NHLAIEQPNT HLPETKPSP
Length:129
Mass (Da):14,675
Last modified:October 13, 2009 - v1
Checksum:i5442D70929D4E87E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
EF514881 Genomic DNA. Translation: ABS84249.1.
EF514882 mRNA. Translation: ABS84250.1.
RefSeqiNP_000210.2. NM_000219.5.
NP_001121140.1. NM_001127668.3.
NP_001121141.1. NM_001127669.3.
NP_001121142.1. NM_001127670.3.
NP_001257331.1. NM_001270402.2.
NP_001257332.1. NM_001270403.2.
NP_001257333.1. NM_001270404.2.
NP_001257334.1. NM_001270405.2.
UniGeneiHs.121495.
Hs.745384.

Genome annotation databases

GeneIDi3753.
KEGGihsa:3753.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
EF514881 Genomic DNA. Translation: ABS84249.1 .
EF514882 mRNA. Translation: ABS84250.1 .
RefSeqi NP_000210.2. NM_000219.5.
NP_001121140.1. NM_001127668.3.
NP_001121141.1. NM_001127669.3.
NP_001121142.1. NM_001127670.3.
NP_001257331.1. NM_001270402.2.
NP_001257332.1. NM_001270403.2.
NP_001257333.1. NM_001270404.2.
NP_001257334.1. NM_001270405.2.
UniGenei Hs.121495.
Hs.745384.

3D structure databases

ProteinModelPortali C7S316.
SMRi C7S316. Positions 1-129.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

DNASUi 3753.
Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3753.
KEGGi hsa:3753.

Organism-specific databases

CTDi 3753.
PharmGKBi PA211.

Phylogenomic databases

KOi K04894.
OMAi SYRACYV.
PhylomeDBi C7S316.

Miscellaneous databases

GenomeRNAii 3753.
NextBioi 14697.

Gene expression databases

ExpressionAtlasi C7S316. baseline.

Family and domain databases

InterProi IPR000369. K_chnl_volt-dep_bsu_KCNE.
IPR005424. K_chnl_volt-dep_bsu_KCNE1.
[Graphical view ]
PANTHERi PTHR17028. PTHR17028. 1 hit.
Pfami PF02060. ISK_Channel. 1 hit.
[Graphical view ]
PRINTSi PR01604. KCNE1CHANNEL.
PR00168. KCNECHANNEL.
ProtoNeti Search...

Publicationsi

  1. "Positive selection at codon 38 of the human KCNE1 (= minK) gene and sporadic absence of 38Ser-coding mRNAs in Gly38Ser heterozygotes."
    Herlyn H., Zechner U., Oswald F., Pfeufer A., Zischler H., Haaf T.
    BMC Evol. Biol. 9:188-188(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiC7S316_HUMAN
AccessioniPrimary (citable) accession number: C7S316
Entry historyi
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: October 29, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.