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Protein
Submitted name:

Potassium voltage-gated channel Isk-related family member 1

Gene

KCNE1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Potassium voltage-gated channel Isk-related family member 1Imported
Gene namesi
Name:KCNE1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA211.

PTM / Processingi

Proteomic databases

PRIDEiC7S316.

Expressioni

Gene expression databases

BgeeiC7S316.
ExpressionAtlasiC7S316. baseline.
GenevisibleiC7S316. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000337255.

Structurei

3D structure databases

ProteinModelPortaliC7S316.
SMRiC7S316. Positions 1-129.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

KOiK04894.
OMAiALYILMV.
PhylomeDBiC7S316.

Family and domain databases

InterProiIPR000369. K_chnl_KCNE.
IPR005424. K_chnl_volt-dep_bsu_KCNE1.
[Graphical view]
PANTHERiPTHR17028. PTHR17028. 1 hit.
PfamiPF02060. ISK_Channel. 1 hit.
[Graphical view]
PRINTSiPR01604. KCNE1CHANNEL.
PR00168. KCNECHANNEL.

Sequencei

Sequence statusi: Complete.

C7S316-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MILSNTTAVT PFLTKLWQET VQQGGNMSGL ARRSPRSSDG KLEALYVLMV
60 70 80 90 100
LGFFGFFTLG IMLSYIRSKK LEHSNDPFNV YIESDAWQEK DKAYVQARVL
110 120
ESYRSCYVVE NHLAIEQPNT HLPETKPSP
Length:129
Mass (Da):14,675
Last modified:October 13, 2009 - v1
Checksum:i5442D70929D4E87E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF514881 Genomic DNA. Translation: ABS84249.1.
EF514882 mRNA. Translation: ABS84250.1.
RefSeqiNP_000210.2. NM_000219.5.
NP_001121140.1. NM_001127668.3.
NP_001121141.1. NM_001127669.3.
NP_001121142.1. NM_001127670.3.
NP_001257331.1. NM_001270402.2.
NP_001257332.1. NM_001270403.2.
NP_001257333.1. NM_001270404.2.
NP_001257334.1. NM_001270405.2.
UniGeneiHs.121495.
Hs.745384.

Genome annotation databases

GeneIDi3753.
KEGGihsa:3753.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF514881 Genomic DNA. Translation: ABS84249.1.
EF514882 mRNA. Translation: ABS84250.1.
RefSeqiNP_000210.2. NM_000219.5.
NP_001121140.1. NM_001127668.3.
NP_001121141.1. NM_001127669.3.
NP_001121142.1. NM_001127670.3.
NP_001257331.1. NM_001270402.2.
NP_001257332.1. NM_001270403.2.
NP_001257333.1. NM_001270404.2.
NP_001257334.1. NM_001270405.2.
UniGeneiHs.121495.
Hs.745384.

3D structure databases

ProteinModelPortaliC7S316.
SMRiC7S316. Positions 1-129.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000337255.

Chemistry

BindingDBiC7S316.

Proteomic databases

PRIDEiC7S316.

Protocols and materials databases

DNASUi3753.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3753.
KEGGihsa:3753.

Organism-specific databases

CTDi3753.
PharmGKBiPA211.

Phylogenomic databases

KOiK04894.
OMAiALYILMV.
PhylomeDBiC7S316.

Miscellaneous databases

ChiTaRSiKCNE1. human.
GenomeRNAii3753.
NextBioi14697.

Gene expression databases

BgeeiC7S316.
ExpressionAtlasiC7S316. baseline.
GenevisibleiC7S316. HS.

Family and domain databases

InterProiIPR000369. K_chnl_KCNE.
IPR005424. K_chnl_volt-dep_bsu_KCNE1.
[Graphical view]
PANTHERiPTHR17028. PTHR17028. 1 hit.
PfamiPF02060. ISK_Channel. 1 hit.
[Graphical view]
PRINTSiPR01604. KCNE1CHANNEL.
PR00168. KCNECHANNEL.
ProtoNetiSearch...

Publicationsi

  1. "Positive selection at codon 38 of the human KCNE1 (= minK) gene and sporadic absence of 38Ser-coding mRNAs in Gly38Ser heterozygotes."
    Herlyn H., Zechner U., Oswald F., Pfeufer A., Zischler H., Haaf T.
    BMC Evol. Biol. 9:188-188(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiC7S316_HUMAN
AccessioniPrimary (citable) accession number: C7S316
Entry historyi
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: June 24, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.