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C7S316

- C7S316_HUMAN

UniProt

C7S316 - C7S316_HUMAN

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Protein
Submitted name:

Potassium voltage-gated channel Isk-related family member 1

Gene
KCNE1
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. delayed rectifier potassium channel activity Source: Ensembl

GO - Biological processi

  1. cellular response to acidity Source: Ensembl
  2. epithelial cell maturation Source: Ensembl
  3. heart contraction Source: Ensembl
  4. male gonad development Source: Ensembl
  5. negative regulation of protein targeting to membrane Source: Ensembl
  6. positive regulation of potassium ion transmembrane transport Source: Ensembl
  7. regulation of heart rate by cardiac conduction Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Potassium voltage-gated channel Isk-related family member 1Imported
Gene namesi
Name:KCNE1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. apical plasma membrane Source: Ensembl
  2. endoplasmic reticulum Source: Ensembl
  3. voltage-gated potassium channel complex Source: Ensembl
  4. Z disc Source: Ensembl
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA211.

Family & Domainsi

Phylogenomic databases

KOiK04894.
OMAiSYRACYV.

Family and domain databases

InterProiIPR000369. K_chnl_volt-dep_bsu_KCNE.
IPR005424. K_chnl_volt-dep_bsu_KCNE1.
[Graphical view]
PANTHERiPTHR17028. PTHR17028. 1 hit.
PfamiPF02060. ISK_Channel. 1 hit.
[Graphical view]
PRINTSiPR01604. KCNE1CHANNEL.
PR00168. KCNECHANNEL.

Sequencei

Sequence statusi: Complete.

C7S316-1 [UniParc]FASTAAdd to Basket

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MILSNTTAVT PFLTKLWQET VQQGGNMSGL ARRSPRSSDG KLEALYVLMV    50
LGFFGFFTLG IMLSYIRSKK LEHSNDPFNV YIESDAWQEK DKAYVQARVL 100
ESYRSCYVVE NHLAIEQPNT HLPETKPSP 129
Length:129
Mass (Da):14,675
Last modified:October 13, 2009 - v1
Checksum:i5442D70929D4E87E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
EF514881 Genomic DNA. Translation: ABS84249.1.
EF514882 mRNA. Translation: ABS84250.1.
RefSeqiNP_000210.2. NM_000219.5.
NP_001121140.1. NM_001127668.3.
NP_001121141.1. NM_001127669.3.
NP_001121142.1. NM_001127670.3.
NP_001257331.1. NM_001270402.2.
NP_001257332.1. NM_001270403.2.
NP_001257333.1. NM_001270404.2.
NP_001257334.1. NM_001270405.2.
UniGeneiHs.121495.
Hs.745384.

Genome annotation databases

GeneIDi3753.
KEGGihsa:3753.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
EF514881 Genomic DNA. Translation: ABS84249.1 .
EF514882 mRNA. Translation: ABS84250.1 .
RefSeqi NP_000210.2. NM_000219.5.
NP_001121140.1. NM_001127668.3.
NP_001121141.1. NM_001127669.3.
NP_001121142.1. NM_001127670.3.
NP_001257331.1. NM_001270402.2.
NP_001257332.1. NM_001270403.2.
NP_001257333.1. NM_001270404.2.
NP_001257334.1. NM_001270405.2.
UniGenei Hs.121495.
Hs.745384.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

DNASUi 3753.
Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3753.
KEGGi hsa:3753.

Organism-specific databases

CTDi 3753.
PharmGKBi PA211.

Phylogenomic databases

KOi K04894.
OMAi SYRACYV.

Miscellaneous databases

GenomeRNAii 3753.
NextBioi 14697.

Family and domain databases

InterProi IPR000369. K_chnl_volt-dep_bsu_KCNE.
IPR005424. K_chnl_volt-dep_bsu_KCNE1.
[Graphical view ]
PANTHERi PTHR17028. PTHR17028. 1 hit.
Pfami PF02060. ISK_Channel. 1 hit.
[Graphical view ]
PRINTSi PR01604. KCNE1CHANNEL.
PR00168. KCNECHANNEL.
ProtoNeti Search...

Publicationsi

  1. "Positive selection at codon 38 of the human KCNE1 (= minK) gene and sporadic absence of 38Ser-coding mRNAs in Gly38Ser heterozygotes."
    Herlyn H., Zechner U., Oswald F., Pfeufer A., Zischler H., Haaf T.
    BMC Evol. Biol. 9:188-188(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiC7S316_HUMAN
AccessioniPrimary (citable) accession number: C7S316
Entry historyi
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: September 3, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.