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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Accumulibacter phosphatis (strain UW-1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei148 – 1481UniRule annotation
Active sitei581 – 5811UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciAPHO522306:GHXL-1523-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:CAP2UW1_1517Imported
OrganismiAccumulibacter phosphatis (strain UW-1)Imported
Taxonomic identifieri522306 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaCandidatus Accumulibacter
ProteomesiUP000001619 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi522306.CAP2UW1_1517.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C7RT89-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEAFPEDKD LPLREDIRLL GRLLGDTLRA QEGEATFELV ERIRVSAIRF
60 70 80 90 100
HRDEDSGARQ ELAAILDSLS RDQTQTVVRA FSHFSHLANI AEDQHHIRRS
110 120 130 140 150
RAHLIAGSPP HAGSLAHALA RARAAGCDVA QLYGFFDDAS IVPVLTAHPT
160 170 180 190 200
EVQRKSTLNG QRAIAHLLHR RDNSRLTPDE QESLDEGLRR AVLALWQTRM
210 220 230 240 250
LRTTRLMVLD EVANGLSYYD YTFLRELPRL YCWLEDHLAA ADGGRPASEL
260 270 280 290 300
PGFLQLGSWM GGDRDGNPFV TAPVTRAALR LQSACALRFH LDEIHALGAE
310 320 330 340 350
LSLAEGLVSV SDALQSLADS SPDTAAARSD EPYRRALTGI YARLAATARK
360 370 380 390 400
LDGLEPERHP VGESAPYANC GEFAADLDVI HRSLVANGSQ LLARGRLRTL
410 420 430 440 450
RRAARVFGFH LAALDLRQNS EVHERVVGEL LEAASPGTNY REHDEAGRVE
460 470 480 490 500
LLLREISSTR PLASSHLAYS DETRGELEIF RTAADAHRAF GSQAVQNYII
510 520 530 540 550
SKTDGVSDLL EVALLLKECG LLLPQSRELA VNIVPLFETI PDLRNCPRVM
560 570 580 590 600
DEVLSLPAYR RLVASRGDLQ EVMLGYSDSN KDGGFLTSGW ELYRAEIALV
610 620 630 640 650
EVFARHGVKL RLFHGRGGSV GRGGGPSYQA ILAQPGGAVQ GRLRLTEQGE
660 670 680 690 700
VIASKYSNPE VGRRNLEILA SAVLEATLLA APDPAPQPEY LEAMAMLSQS
710 720 730 740 750
AYRAYRGLVY ETEGFERYFW ESTVIAEIAH LNIGSRPASR KKTTAIEDLR
760 770 780 790 800
AIPWVFSWAQ CRLMLPGWYG FGTAVREFLA VHPEGLEVLQ RMHHEWGFFR
810 820 830 840 850
TLLSNMDMVL AKTDLAIAAR YAELVTDPAL RAAIFPRLKA EWQATIDALL
860 870 880 890 900
AISGQQCLLE DNPLLARSIR NRFPYLDPLN HLQIELIRRL RAGNEDERVK
910
RAIHLTINGI AAGLRNSG
Length:918
Mass (Da):101,697
Last modified:October 13, 2009 - v1
Checksum:i2BC6791B5AEA8DC0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001715 Genomic DNA. Translation: ACV34832.1.
RefSeqiWP_015766053.1. NC_013194.1.

Genome annotation databases

EnsemblBacteriaiACV34832; ACV34832; CAP2UW1_1517.
KEGGiapp:CAP2UW1_1517.
PATRICi21259091. VBICanAcc132554_1805.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001715 Genomic DNA. Translation: ACV34832.1.
RefSeqiWP_015766053.1. NC_013194.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi522306.CAP2UW1_1517.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACV34832; ACV34832; CAP2UW1_1517.
KEGGiapp:CAP2UW1_1517.
PATRICi21259091. VBICanAcc132554_1805.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciAPHO522306:GHXL-1523-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome of Candidatus Accumulibacter phosphatis clade IIA str. UW-1."
    US DOE Joint Genome Institute
    Martin H.G., Ivanova N., Kunin V., Warnecke F., Barry K., He S., Salamov A., Szeto E., Dalin E., Pangilinan J.L., Lapidus A., Lowry S., Kyrpides N.C., McMahon K.D., Hugenholtz P.
    Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: UW-1Imported.

Entry informationi

Entry nameiC7RT89_ACCPU
AccessioniPrimary (citable) accession number: C7RT89
Entry historyi
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: July 22, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.