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C7RSN4

- C7RSN4_ACCPU

UniProt

C7RSN4 - C7RSN4_ACCPU

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Protein
Alanine racemase
Gene
CAP2UW1_2650
Organism
Accumulibacter phosphatis (strain UW-1)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei39 – 391Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei135 – 1351Substrate By similarityUniRule annotation
Active sitei264 – 2641Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei312 – 3121Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciAPHO522306:GHXL-2676-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:CAP2UW1_2650Imported
OrganismiAccumulibacter phosphatis (strain UW-1)Imported
Taxonomic identifieri522306 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaCandidatus Accumulibacter
ProteomesiUP000001619: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei39 – 391N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi522306.CAP2UW1_2650.

Structurei

3D structure databases

ProteinModelPortaliC7RSN4.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031446.
KOiK01775.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C7RSN4-1 [UniParc]FASTAAdd to Basket

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MPRPIAARID GGALRHNYLL ARNQARRGEG RARAWAVVKA NAYGHGLLRA    50
ARALADVADG FALLDLEEAV RLRDAGIRQP ILLLEGFFEA ADLAVCAAHD 100
LTLVVHRLEQ LQMLRRASLP VRLPIFLKLN SGMNRLGLTA AELPAVRREL 150
AASPAVSAVT LMTHFAEADG DGGEACITWQ LERFAGMLAD WPEAATWPVS 200
LANSAAILRY PQTARDWVRP GIMLYGGSPF ADQDAASLGL KPVMTLHSRI 250
LAVQEIAVGE RVGYGGTFVA RRPTRVGVVA CGYADGYPRH APGGTPIVVA 300
GQATTTLGRV SMDMLACDLT DLPAAGVNSP VVLWGEGLAA DAVAAAAGTI 350
SYELFCALAR RVPVVEV 367
Length:367
Mass (Da):38,966
Last modified:October 13, 2009 - v1
Checksum:i86B56C528F5AB78D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001715 Genomic DNA. Translation: ACV35936.1.
RefSeqiYP_003167865.1. NC_013194.1.

Genome annotation databases

EnsemblBacteriaiACV35936; ACV35936; CAP2UW1_2650.
GeneIDi8404809.
KEGGiapp:CAP2UW1_2650.
PATRICi21261483. VBICanAcc132554_2980.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001715 Genomic DNA. Translation: ACV35936.1 .
RefSeqi YP_003167865.1. NC_013194.1.

3D structure databases

ProteinModelPortali C7RSN4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 522306.CAP2UW1_2650.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACV35936 ; ACV35936 ; CAP2UW1_2650 .
GeneIDi 8404809.
KEGGi app:CAP2UW1_2650.
PATRICi 21261483. VBICanAcc132554_2980.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000031446.
KOi K01775.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci APHO522306:GHXL-2676-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome of Candidatus Accumulibacter phosphatis clade IIA str. UW-1."
    US DOE Joint Genome Institute
    Martin H.G., Ivanova N., Kunin V., Warnecke F., Barry K., He S., Salamov A., Szeto E., Dalin E., Pangilinan J.L., Lapidus A., Lowry S., Kyrpides N.C., McMahon K.D., Hugenholtz P.
    Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: UW-1Imported.

Entry informationi

Entry nameiC7RSN4_ACCPU
AccessioniPrimary (citable) accession number: C7RSN4
Entry historyi
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: July 9, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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