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C7RB77

- C7RB77_KANKD

UniProt

C7RB77 - C7RB77_KANKD

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Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene

Kkor_1100

Organism
Kangiella koreensis (strain DSM 16069 / KCTC 12182 / SW-125)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei145 – 1451Substrate
Sitei255 – 2551Critical for catalysisUniRule annotation
Metal bindingi350 – 3501Magnesium or manganeseUniRule annotation
Sitei420 – 4201Critical for catalysisUniRule annotation
Binding sitei547 – 5471Substrate
Metal bindingi548 – 5481Magnesium or manganeseUniRule annotation
Metal bindingi552 – 5521Magnesium or manganeseUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciKKOR523791:GHCO-1126-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
Gene namesi
Ordered Locus Names:Kkor_1100Imported
OrganismiKangiella koreensis (strain DSM 16069 / KCTC 12182 / SW-125)Imported
Taxonomic identifieri523791 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesAlcanivoracaceaeKangiella
ProteomesiUP000001231: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi523791.Kkor_1100.

Structurei

3D structure databases

ProteinModelPortaliC7RB77.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni132 – 1398Substrate bindingUniRule annotation

Phylogenomic databases

eggNOGiCOG2838.
HOGENOMiHOG000240860.
KOiK00031.
OMAiEEQRIGD.
OrthoDBiEOG6DVJPP.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

C7RB77-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTSSKIIYTK TDEAPALATY SLLPIVEAFA KAAGIEVETS DISLAGRVIA
60 70 80 90 100
SFPEYLKEEQ RIPDALAELG ELVKKPEANI IKLPNISASI PQLKATIKEL
110 120 130 140 150
QDKGYALPDY PDNASSDEEK DIRNRYDKIK GSAVNPVLRE GNSDRRAPNA
160 170 180 190 200
VKNYAKKNPH SMGEWSKDSK SHVASMQSGD FFSNEKSITV DGNNDVKIEF
210 220 230 240 250
VGNDGSKQVL KESTPLLAGE VIDATVLNKN ALVKFLEEQV EDAKKQDVLF
260 270 280 290 300
SLHMKATMMK VSDPIIFGHG VKVFFKDVFE KHADALAQVG ANPNNGFGNV
310 320 330 340 350
LSAIESLPAE KRDEIKADIE AVYAKNPELA MVNSDKGITN LHVPSDVIID
360 370 380 390 400
ASMPAMIRTS GMMWGPDGQP KDTKAVIPDS SYSGVYSATI DFCREHGAFD
410 420 430 440 450
PRTMGTVPNV GLMAQKAEEY GSHDKTFEMT GNGHVRVTDK DGNVVLEHAV
460 470 480 490 500
EEGDIWRMCQ VKDAPIRDWV KLAVTRSRLS GMPAVFWLDK NRAHDAQLIQ
510 520 530 540 550
KVETYLKDHD TSGLEIHIMS PVDATKFTLQ RMKDGKDTIS VTGNVLRDYL
560 570 580 590 600
TDLFPILELG TSAKMLSIVP LMNGGGLFET GAGGSAPKHV QQFMEENHLR
610 620 630 640 650
WDSLGEFLAL AVSFEHMAQT TNNKKAQVLA DTLDRATGKF LDNGKSPSRK
660 670 680 690 700
VNELDNRGSH FYLAMYWAQE LASQTDDAEL KGLFAKVSEA LTSNEAKIVD
710 720 730 740
ELNAVQGQAM DIGGYYKPDD NLGFKAMRPS TTLNTALELI
Length:740
Mass (Da):81,223
Last modified:October 13, 2009 - v1
Checksum:i1D5F7D181DB841EA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001707 Genomic DNA. Translation: ACV26519.1.
RefSeqiYP_003146287.1. NC_013166.1.

Genome annotation databases

EnsemblBacteriaiACV26519; ACV26519; Kkor_1100.
GeneIDi8369894.
KEGGikko:Kkor_1100.
PATRICi22167640. VBIKanKor123990_1088.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001707 Genomic DNA. Translation: ACV26519.1 .
RefSeqi YP_003146287.1. NC_013166.1.

3D structure databases

ProteinModelPortali C7RB77.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 523791.Kkor_1100.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACV26519 ; ACV26519 ; Kkor_1100 .
GeneIDi 8369894.
KEGGi kko:Kkor_1100.
PATRICi 22167640. VBIKanKor123990_1088.

Phylogenomic databases

eggNOGi COG2838.
HOGENOMi HOG000240860.
KOi K00031.
OMAi EEQRIGD.
OrthoDBi EOG6DVJPP.

Enzyme and pathway databases

BioCyci KKOR523791:GHCO-1126-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 16069 / KCTC 12182 / SW-125Imported.

Entry informationi

Entry nameiC7RB77_KANKD
AccessioniPrimary (citable) accession number: C7RB77
Entry historyi
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: October 29, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3