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C7RB77

- C7RB77_KANKD

UniProt

C7RB77 - C7RB77_KANKD

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Protein
Submitted name: Isocitrate dehydrogenase, NADP-dependent
Gene
Kkor_1100
Organism
Kangiella koreensis (strain DSM 16069 / KCTC 12182 / SW-125)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei145 – 1451Substrate By similarityUniRule annotation
Sitei255 – 2551Critical for catalysis By similarityUniRule annotation
Metal bindingi350 – 3501Magnesium or manganese By similarity
Sitei420 – 4201Critical for catalysis By similarityUniRule annotation
Binding sitei547 – 5471Substrate By similarityUniRule annotation
Metal bindingi548 – 5481Magnesium or manganese By similarity
Metal bindingi552 – 5521Magnesium or manganese By similarity

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciKKOR523791:GHCO-1126-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
Gene namesi
Ordered Locus Names:Kkor_1100Imported
OrganismiKangiella koreensis (strain DSM 16069 / KCTC 12182 / SW-125)Imported
Taxonomic identifieri523791 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesAlcanivoracaceaeKangiella
ProteomesiUP000001231: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi523791.Kkor_1100.

Structurei

3D structure databases

ProteinModelPortaliC7RB77.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni132 – 1398Substrate binding By similarityUniRule annotation

Phylogenomic databases

eggNOGiCOG2838.
HOGENOMiHOG000240860.
KOiK00031.
OMAiEEQRIGD.
OrthoDBiEOG6DVJPP.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

C7RB77-1 [UniParc]FASTAAdd to Basket

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MTSSKIIYTK TDEAPALATY SLLPIVEAFA KAAGIEVETS DISLAGRVIA    50
SFPEYLKEEQ RIPDALAELG ELVKKPEANI IKLPNISASI PQLKATIKEL 100
QDKGYALPDY PDNASSDEEK DIRNRYDKIK GSAVNPVLRE GNSDRRAPNA 150
VKNYAKKNPH SMGEWSKDSK SHVASMQSGD FFSNEKSITV DGNNDVKIEF 200
VGNDGSKQVL KESTPLLAGE VIDATVLNKN ALVKFLEEQV EDAKKQDVLF 250
SLHMKATMMK VSDPIIFGHG VKVFFKDVFE KHADALAQVG ANPNNGFGNV 300
LSAIESLPAE KRDEIKADIE AVYAKNPELA MVNSDKGITN LHVPSDVIID 350
ASMPAMIRTS GMMWGPDGQP KDTKAVIPDS SYSGVYSATI DFCREHGAFD 400
PRTMGTVPNV GLMAQKAEEY GSHDKTFEMT GNGHVRVTDK DGNVVLEHAV 450
EEGDIWRMCQ VKDAPIRDWV KLAVTRSRLS GMPAVFWLDK NRAHDAQLIQ 500
KVETYLKDHD TSGLEIHIMS PVDATKFTLQ RMKDGKDTIS VTGNVLRDYL 550
TDLFPILELG TSAKMLSIVP LMNGGGLFET GAGGSAPKHV QQFMEENHLR 600
WDSLGEFLAL AVSFEHMAQT TNNKKAQVLA DTLDRATGKF LDNGKSPSRK 650
VNELDNRGSH FYLAMYWAQE LASQTDDAEL KGLFAKVSEA LTSNEAKIVD 700
ELNAVQGQAM DIGGYYKPDD NLGFKAMRPS TTLNTALELI 740
Length:740
Mass (Da):81,223
Last modified:October 13, 2009 - v1
Checksum:i1D5F7D181DB841EA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001707 Genomic DNA. Translation: ACV26519.1.
RefSeqiYP_003146287.1. NC_013166.1.

Genome annotation databases

EnsemblBacteriaiACV26519; ACV26519; Kkor_1100.
GeneIDi8369894.
KEGGikko:Kkor_1100.
PATRICi22167640. VBIKanKor123990_1088.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001707 Genomic DNA. Translation: ACV26519.1 .
RefSeqi YP_003146287.1. NC_013166.1.

3D structure databases

ProteinModelPortali C7RB77.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 523791.Kkor_1100.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACV26519 ; ACV26519 ; Kkor_1100 .
GeneIDi 8369894.
KEGGi kko:Kkor_1100.
PATRICi 22167640. VBIKanKor123990_1088.

Phylogenomic databases

eggNOGi COG2838.
HOGENOMi HOG000240860.
KOi K00031.
OMAi EEQRIGD.
OrthoDBi EOG6DVJPP.

Enzyme and pathway databases

BioCyci KKOR523791:GHCO-1126-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 16069 / KCTC 12182 / SW-125.

Entry informationi

Entry nameiC7RB77_KANKD
AccessioniPrimary (citable) accession number: C7RB77
Entry historyi
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: July 9, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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