Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

C7R3N7 (C7R3N7_JONDD) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
Ordered Locus Names:Jden_2550 EMBL ACV10182.1
OrganismJonesia denitrificans (strain ATCC 14870 / DSM 20603 / CIP 55134) (Listeria denitrificans) [Complete proteome] [HAMAP] EMBL ACV10182.1
Taxonomic identifier471856 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeJonesiaceaeJonesia

Protein attributes

Sequence length319 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS011095

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS011095

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS011095.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011095

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain103 – 308206ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding137 – 19256ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2621Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2751Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2751Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2771Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
C7R3N7 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: 020344C07DE0B491

FASTA31933,829
        10         20         30         40         50         60 
MSSHPFVVIL AGGLSHERDV SLRSGRRVAE ALRSTGMTVS VVDVDAQLLP RLQSHRPDLV 

        70         80         90        100        110        120 
WPLLHGASGE DGSIRDVLEL LDLPYLGTRP RESRVAWNKP VAKAVLAAAG VLTPSYVTLP 

       130        140        150        160        170        180 
QSLFRELGAR SVMEPVTAKL GLPLVVKPAQ GGSALGVTLV TSAEQLPQAL VDCFAYGDLA 

       190        200        210        220        230        240 
LIEEAITGTE VSVSVVESPD VTALPAVEII TDGPYDYDAR YNPGRTQYFT PARLDPEIAD 

       250        260        270        280        290        300 
AAARVALTAH TTLGLRHVSR SDLIIDGKGQ VWFLEVNVAP GMTETSLLPQ AVVASGQSLP 

       310 
DAYSSWVRAA LVVADSAAQ 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001706 Genomic DNA. Translation: ACV10182.1.
RefSeqYP_003162485.1. NC_013174.1.

3D structure databases

ProteinModelPortalC7R3N7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING471856.Jden_2550.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACV10182; ACV10182; Jden_2550.
GeneID8381703.
KEGGjde:Jden_2550.
PATRIC22165397. VBIJonDen9837_2652.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1181.
HOGENOMHOG000011592.
KOK01921.
OMADYTARYT.
OrthoDBEOG6ND0KB.

Enzyme and pathway databases

BioCycJDEN471856:GH77-2630-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC7R3N7_JONDD
AccessionPrimary (citable) accession number: C7R3N7
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: June 11, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)