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C7R322 (C7R322_JONDD) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
tRNA (guanine-N(1)-)-methyltransferase HAMAP MF_00605
EC=2.1.1.228 HAMAP MF_00605
Alternative name(s):
M1G-methyltransferase HAMAP MF_00605
tRNA [GM37] methyltransferase HAMAP MF_00605
Gene names
Name:trmD HAMAP MF_00605
Ordered Locus Names:Jden_0988
OrganismJonesia denitrificans (strain ATCC 14870 / DSM 20603 / CIP 55134) (Listeria denitrificans) [Complete proteome] [HAMAP]
Taxonomic identifier471856 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Jonesiaceae › Jonesia

Protein attributes

Sequence length294 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates guanosine-37 in various tRNAs By similarity. HAMAP MF_00605

Catalytic activity

S-adenosyl-L-methionine + guanine(37) in tRNA = S-adenosyl-L-homocysteine + N(1)-methylguanine(37) in tRNA. HAMAP MF_00605

Subunit structure

Homodimer By similarity. HAMAP MF_00605

Subcellular location

Cytoplasm By similarity HAMAP MF_00605.

Sequence similarities

Belongs to the RNA methyltransferase TrmD family. HAMAP MF_00605

Ontologies

Keywords
   Biological processtRNA processing HAMAP MF_00605
   Cellular componentCytoplasm HAMAP MF_00605
   LigandS-adenosyl-L-methionine HAMAP MF_00605
   Molecular functionMethyltransferase HAMAP MF_00605 EMBL ACV08644.1
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionRNA binding

Inferred from electronic annotation. Source: InterPro

tRNA (guanine-N1-)-methyltransferase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region164 – 1696S-adenosyl-L-methionine binding By similarity HAMAP MF_00605

Sites

Binding site1391S-adenosyl-L-methionine; via amide nitrogen By similarity HAMAP MF_00605

Sequences

Sequence LengthMass (Da)Tools
C7R322 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: 70B70827EE3C126D

FASTA29431,664
        10         20         30         40         50         60 
MIIDVVSIFP DYLAPLGLSL VGKAREQGTV TINVHDLRQW TTDRHRTVDD TPLGGGAGMV 

        70         80         90        100        110        120 
MKPDVWGQAL DSVFAHEELI APHGDKEAAG VVSPDGAVTD GGESPPRRVL IIPTPSGQSF 

       130        140        150        160        170        180 
SQRHAHDLAT VDHIAVACGR YEGIDARVAD HYRDRGIEVA ELSIGDYVLN GGEVAAMVMI 

       190        200        210        220        230        240 
EAIVRLIPGV VGNPHSLVEE SHGEAGLLEY PVFTRPPSWR GLDAPAVLLS GHHGRIARWR 

       250        260        270        280        290 
RDQSLERTAR RRPDMIEALD VTELDAHDQA LLTELGFIVT SHGVCSSSVG DVAQ

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001706 Genomic DNA. Translation: ACV08644.1.
RefSeqYP_003160947.1. NC_013174.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGC7R322.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8380165.
GenomeReviewsGene locus Jden_0988 in contig CP001706_GR.
KEGGjde:Jden_0988.
PATRIC22162070. VBIJonDen9837_1032.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAVCGRFEG.

Family and domain databases

HAMAPMF_00605. TrmD.
[Tree]
InterProIPR016009. tRNA_m1G_MeTrfase.
IPR002649. tRNA_m1G_MeTrfase_bac.
IPR023148. tRNA_m1G_MeTrfase_C.
[Graphical view]
Gene3DG3DSA:1.10.1270.20. tRNA_m1G_MeTrfase_C. 1 hit.
KOK00554.
PANTHERPTHR10056. PTHR10056. 1 hit.
PfamPF01746. tRNA_m1G_MT. 1 hit.
[Graphical view]
PIRSFPIRSF000386. tRNA_mtase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC7R322_JONDD
AccessionPrimary (citable) accession number: C7R322
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: December 14, 2011
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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