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C7R191

- C7R191_JONDD

UniProt

C7R191 - C7R191_JONDD

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Protein

Acetate kinase

Gene

ackA

Organism
Jonesia denitrificans (strain ATCC 14870 / DSM 20603 / CIP 55134) (Listeria denitrificans)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.UniRule annotation

Catalytic activityi

ATP + acetate = ADP + acetyl phosphate.UniRule annotation

Cofactori

Note: Mg(2+). Can also accept Mn(2+).UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi10 – 101MagnesiumUniRule annotation
Binding sitei17 – 171ATPUniRule annotation
Binding sitei91 – 911SubstrateUniRule annotation
Active sitei148 – 1481Proton donor/acceptorUniRule annotation
Sitei180 – 1801Transition state stabilizerUniRule annotation
Sitei241 – 2411Transition state stabilizerUniRule annotation
Metal bindingi385 – 3851MagnesiumUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi208 – 2125ATPUniRule annotation
Nucleotide bindingi282 – 2843ATPUniRule annotation
Nucleotide bindingi331 – 3355ATPUniRule annotation

GO - Molecular functioni

  1. acetate kinase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-KW
  3. magnesium ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. acetyl-CoA biosynthetic process Source: UniProtKB-UniPathway
  2. organic acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciJDEN471856:GH77-660-MONOMER.
UniPathwayiUPA00340; UER00458.

Names & Taxonomyi

Protein namesi
Recommended name:
Acetate kinaseUniRule annotation (EC:2.7.2.1UniRule annotation)
Alternative name(s):
AcetokinaseUniRule annotation
Gene namesi
Name:ackAUniRule annotation
Ordered Locus Names:Jden_0642Imported
OrganismiJonesia denitrificans (strain ATCC 14870 / DSM 20603 / CIP 55134) (Listeria denitrificans)Imported
Taxonomic identifieri471856 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeJonesiaceaeJonesia
ProteomesiUP000000628: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi471856.Jden_0642.

Structurei

3D structure databases

ProteinModelPortaliC7R191.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the acetokinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0282.
HOGENOMiHOG000288399.
KOiK00925.
OMAiKYVTQRA.
OrthoDBiEOG69975F.

Family and domain databases

HAMAPiMF_00020. Acetate_kinase.
InterProiIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
PANTHERiPTHR21060. PTHR21060. 1 hit.
PfamiPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFiPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSiPR00471. ACETATEKNASE.
TIGRFAMsiTIGR00016. ackA. 1 hit.
PROSITEiPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C7R191-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSHATVLVIN AGSSTIKYQL VDPTSGEAIA GGLVERIGES NGLVEHRYHG
60 70 80 90 100
EEHSEELPIT DHGHGLREVL RLFDTHGPRL ADAHIVAVGH RVVQGGSVFP
110 120 130 140 150
HPTVVDDDVV EKIRDLIPLA PLHNPGSVRG IEVARELFSD IPHVVVFDTS
160 170 180 190 200
FFQTMPASAY TYALPKDLAA EHSIRRYGFH GTSHQYVSEQ AALLLGRDLT
210 220 230 240 250
SFNQIVAHLG SGASISAIAG GTAVDTSMGL TPLEGLVMGT RTGDMDPAIV
260 270 280 290 300
LHLQRAAGLS IDEVNTLLNK ESGLKGLCGN NDFREVLAMI EAGNQDAALA
310 320 330 340 350
FDVYVHRLVK YIGSYMAVLG GLPEVITFTA GVGENNALIR ERVADALAGF
360 370 380 390
GVRIDKEANA VRSKEARIVS TPDSTVAVAV IPTNEELAIA RQTLALVEA
Length:399
Mass (Da):42,517
Last modified:October 13, 2009 - v1
Checksum:iCFE10FEF9B9ECD48
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001706 Genomic DNA. Translation: ACV08306.1.
RefSeqiYP_003160609.1. NC_013174.1.

Genome annotation databases

EnsemblBacteriaiACV08306; ACV08306; Jden_0642.
GeneIDi8379827.
KEGGijde:Jden_0642.
PATRICi22161332. VBIJonDen9837_0674.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001706 Genomic DNA. Translation: ACV08306.1 .
RefSeqi YP_003160609.1. NC_013174.1.

3D structure databases

ProteinModelPortali C7R191.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 471856.Jden_0642.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACV08306 ; ACV08306 ; Jden_0642 .
GeneIDi 8379827.
KEGGi jde:Jden_0642.
PATRICi 22161332. VBIJonDen9837_0674.

Phylogenomic databases

eggNOGi COG0282.
HOGENOMi HOG000288399.
KOi K00925.
OMAi KYVTQRA.
OrthoDBi EOG69975F.

Enzyme and pathway databases

UniPathwayi UPA00340 ; UER00458 .
BioCyci JDEN471856:GH77-660-MONOMER.

Family and domain databases

HAMAPi MF_00020. Acetate_kinase.
InterProi IPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view ]
PANTHERi PTHR21060. PTHR21060. 1 hit.
Pfami PF00871. Acetate_kinase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSi PR00471. ACETATEKNASE.
TIGRFAMsi TIGR00016. ackA. 1 hit.
PROSITEi PS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 14870 / DSM 20603 / CIP 55134Imported.

Entry informationi

Entry nameiC7R191_JONDD
AccessioniPrimary (citable) accession number: C7R191
Entry historyi
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: November 26, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3