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C7R191

- C7R191_JONDD

UniProt

C7R191 - C7R191_JONDD

Protein

Acetate kinase

Gene

ackA

Organism
Jonesia denitrificans (strain ATCC 14870 / DSM 20603 / CIP 55134) (Listeria denitrificans)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (13 Oct 2009)
      Previous versions | rss
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    Functioni

    Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.UniRule annotation

    Catalytic activityi

    ATP + acetate = ADP + acetyl phosphate.UniRule annotation

    Cofactori

    Mg2+. Can also accept Mn2+.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi10 – 101MagnesiumUniRule annotation
    Binding sitei17 – 171ATPUniRule annotation
    Binding sitei91 – 911SubstrateUniRule annotation
    Active sitei148 – 1481Proton donor/acceptorUniRule annotation
    Sitei180 – 1801Transition state stabilizerUniRule annotation
    Sitei241 – 2411Transition state stabilizerUniRule annotation
    Metal bindingi385 – 3851MagnesiumUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi208 – 2125ATPUniRule annotation
    Nucleotide bindingi282 – 2843ATPUniRule annotation
    Nucleotide bindingi331 – 3355ATPUniRule annotation

    GO - Molecular functioni

    1. acetate kinase activity Source: UniProtKB-HAMAP
    2. ATP binding Source: UniProtKB-KW
    3. magnesium ion binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. acetyl-CoA biosynthetic process Source: UniProtKB-UniPathway
    2. organic acid metabolic process Source: InterPro

    Keywords - Molecular functioni

    KinaseUniRule annotationSAAS annotationImported, Transferase

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciJDEN471856:GH77-660-MONOMER.
    UniPathwayiUPA00340; UER00458.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acetate kinaseUniRule annotation (EC:2.7.2.1UniRule annotation)
    Alternative name(s):
    AcetokinaseUniRule annotation
    Gene namesi
    Name:ackAUniRule annotation
    Ordered Locus Names:Jden_0642Imported
    OrganismiJonesia denitrificans (strain ATCC 14870 / DSM 20603 / CIP 55134) (Listeria denitrificans)Imported
    Taxonomic identifieri471856 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeJonesiaceaeJonesia
    ProteomesiUP000000628: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi471856.Jden_0642.

    Structurei

    3D structure databases

    ProteinModelPortaliC7R191.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the acetokinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0282.
    HOGENOMiHOG000288399.
    KOiK00925.
    OMAiKYVTQRA.
    OrthoDBiEOG69975F.

    Family and domain databases

    HAMAPiMF_00020. Acetate_kinase.
    InterProiIPR004372. Ac/Proprionate_kinase.
    IPR000890. Aliphatic_acid_kin_short-chain.
    IPR023865. Aliphatic_acid_kinase_CS.
    [Graphical view]
    PANTHERiPTHR21060. PTHR21060. 1 hit.
    PfamiPF00871. Acetate_kinase. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000722. Acetate_prop_kin. 1 hit.
    PRINTSiPR00471. ACETATEKNASE.
    TIGRFAMsiTIGR00016. ackA. 1 hit.
    PROSITEiPS01075. ACETATE_KINASE_1. 1 hit.
    PS01076. ACETATE_KINASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C7R191-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSHATVLVIN AGSSTIKYQL VDPTSGEAIA GGLVERIGES NGLVEHRYHG    50
    EEHSEELPIT DHGHGLREVL RLFDTHGPRL ADAHIVAVGH RVVQGGSVFP 100
    HPTVVDDDVV EKIRDLIPLA PLHNPGSVRG IEVARELFSD IPHVVVFDTS 150
    FFQTMPASAY TYALPKDLAA EHSIRRYGFH GTSHQYVSEQ AALLLGRDLT 200
    SFNQIVAHLG SGASISAIAG GTAVDTSMGL TPLEGLVMGT RTGDMDPAIV 250
    LHLQRAAGLS IDEVNTLLNK ESGLKGLCGN NDFREVLAMI EAGNQDAALA 300
    FDVYVHRLVK YIGSYMAVLG GLPEVITFTA GVGENNALIR ERVADALAGF 350
    GVRIDKEANA VRSKEARIVS TPDSTVAVAV IPTNEELAIA RQTLALVEA 399
    Length:399
    Mass (Da):42,517
    Last modified:October 13, 2009 - v1
    Checksum:iCFE10FEF9B9ECD48
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001706 Genomic DNA. Translation: ACV08306.1.
    RefSeqiYP_003160609.1. NC_013174.1.

    Genome annotation databases

    EnsemblBacteriaiACV08306; ACV08306; Jden_0642.
    GeneIDi8379827.
    KEGGijde:Jden_0642.
    PATRICi22161332. VBIJonDen9837_0674.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001706 Genomic DNA. Translation: ACV08306.1 .
    RefSeqi YP_003160609.1. NC_013174.1.

    3D structure databases

    ProteinModelPortali C7R191.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 471856.Jden_0642.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACV08306 ; ACV08306 ; Jden_0642 .
    GeneIDi 8379827.
    KEGGi jde:Jden_0642.
    PATRICi 22161332. VBIJonDen9837_0674.

    Phylogenomic databases

    eggNOGi COG0282.
    HOGENOMi HOG000288399.
    KOi K00925.
    OMAi KYVTQRA.
    OrthoDBi EOG69975F.

    Enzyme and pathway databases

    UniPathwayi UPA00340 ; UER00458 .
    BioCyci JDEN471856:GH77-660-MONOMER.

    Family and domain databases

    HAMAPi MF_00020. Acetate_kinase.
    InterProi IPR004372. Ac/Proprionate_kinase.
    IPR000890. Aliphatic_acid_kin_short-chain.
    IPR023865. Aliphatic_acid_kinase_CS.
    [Graphical view ]
    PANTHERi PTHR21060. PTHR21060. 1 hit.
    Pfami PF00871. Acetate_kinase. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000722. Acetate_prop_kin. 1 hit.
    PRINTSi PR00471. ACETATEKNASE.
    TIGRFAMsi TIGR00016. ackA. 1 hit.
    PROSITEi PS01075. ACETATE_KINASE_1. 1 hit.
    PS01076. ACETATE_KINASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 14870 / DSM 20603 / CIP 55134Imported.

    Entry informationi

    Entry nameiC7R191_JONDD
    AccessioniPrimary (citable) accession number: C7R191
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 13, 2009
    Last sequence update: October 13, 2009
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3