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C7R191 (C7R191_JONDD) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase HAMAP-Rule MF_00020
EC=2.7.2.1 HAMAP-Rule MF_00020
Alternative name(s):
Acetokinase HAMAP-Rule MF_00020
Gene names
Name:ackA HAMAP-Rule MF_00020
Ordered Locus Names:Jden_0642
OrganismJonesia denitrificans (strain ATCC 14870 / DSM 20603 / CIP 55134) (Listeria denitrificans) [Complete proteome] [HAMAP]
Taxonomic identifier471856 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Jonesiaceae › Jonesia ›

Protein attributes

Sequence length399 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction By similarity. HAMAP-Rule MF_00020

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP-Rule MF_00020

Cofactor

Mg2+. Can also accept Mn2+ By similarity. HAMAP-Rule MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP-Rule MF_00020

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00020

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00020 SAAS SAAS000890.

Sequence similarities

Belongs to the acetokinase family. RuleBase RU003835

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding208 – 2125ATP By similarity HAMAP-Rule MF_00020
Nucleotide binding282 – 2843ATP By similarity HAMAP-Rule MF_00020
Nucleotide binding331 – 3355ATP By similarity HAMAP-Rule MF_00020

Sites

Active site1481Proton donor/acceptor By similarity HAMAP-Rule MF_00020
Metal binding101Magnesium By similarity HAMAP-Rule MF_00020
Metal binding3851Magnesium By similarity HAMAP-Rule MF_00020
Binding site171ATP By similarity HAMAP-Rule MF_00020
Binding site911Substrate By similarity HAMAP-Rule MF_00020
Site1801Transition state stabilizer By similarity HAMAP-Rule MF_00020
Site2411Transition state stabilizer By similarity HAMAP-Rule MF_00020

Sequences

Sequence LengthMass (Da)Tools
C7R191 [UniParc].

Last modified October 13, 2009. Version 1.
Checksum: CFE10FEF9B9ECD48

FASTA39942,517
        10         20         30         40         50         60 
MSHATVLVIN AGSSTIKYQL VDPTSGEAIA GGLVERIGES NGLVEHRYHG EEHSEELPIT 

        70         80         90        100        110        120 
DHGHGLREVL RLFDTHGPRL ADAHIVAVGH RVVQGGSVFP HPTVVDDDVV EKIRDLIPLA 

       130        140        150        160        170        180 
PLHNPGSVRG IEVARELFSD IPHVVVFDTS FFQTMPASAY TYALPKDLAA EHSIRRYGFH 

       190        200        210        220        230        240 
GTSHQYVSEQ AALLLGRDLT SFNQIVAHLG SGASISAIAG GTAVDTSMGL TPLEGLVMGT 

       250        260        270        280        290        300 
RTGDMDPAIV LHLQRAAGLS IDEVNTLLNK ESGLKGLCGN NDFREVLAMI EAGNQDAALA 

       310        320        330        340        350        360 
FDVYVHRLVK YIGSYMAVLG GLPEVITFTA GVGENNALIR ERVADALAGF GVRIDKEANA 

       370        380        390 
VRSKEARIVS TPDSTVAVAV IPTNEELAIA RQTLALVEA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001706 Genomic DNA. Translation: ACV08306.1.
RefSeqYP_003160609.1. NC_013174.1.

3D structure databases

ProteinModelPortalC7R191.
ModBaseSearch...

Protein-protein interaction databases

STRING471856.Jden_0642.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACV08306; ACV08306; Jden_0642.
GeneID8379827.
KEGGjde:Jden_0642.
PATRIC22161332. VBIJonDen9837_0674.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0282.
HOGENOMHOG000288399.
KOK00925.
OMARSKEARI.

Enzyme and pathway databases

BioCycJDEN471856:GH77-660-MONOMER.
UniPathwayUPA00340; UER00458.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
PANTHERPTHR21060. PTHR21060. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. ackA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC7R191_JONDD
AccessionPrimary (citable) accession number: C7R191
Entry history
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: May 29, 2013
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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