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C7R176

- C7R176_JONDD

UniProt

C7R176 - C7R176_JONDD

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Protein

Alanine racemase

Gene

Jden_0627

Organism
Jonesia denitrificans (strain ATCC 14870 / DSM 20603 / CIP 55134) (Listeria denitrificans)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei48 – 481Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei146 – 1461SubstrateUniRule annotation
Active sitei280 – 2801Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei333 – 3331Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciJDEN471856:GH77-645-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Jden_0627Imported
OrganismiJonesia denitrificans (strain ATCC 14870 / DSM 20603 / CIP 55134) (Listeria denitrificans)Imported
Taxonomic identifieri471856 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeJonesiaceaeJonesia
ProteomesiUP000000628: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei48 – 481N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi471856.Jden_0627.

Structurei

3D structure databases

ProteinModelPortaliC7R176.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031444.
KOiK01775.
OMAiLWQLEAI.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C7R176-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSDNHQPPPG TYPGRAIIDL AAISQNVSTL ATRLGDNGSH AAIMAVVKAN
60 70 80 90 100
AYGHGLVPAA RAALHGGATW LGVAHAHEAL ALRQAGITDR ILTWLHAPGV
110 120 130 140 150
PYRDLIAADI DVSVAAPWAA QEVISAAQAA GRPARVHLKV DTGLGRNGVT
160 170 180 190 200
PADLPFLLAT LIDAQHAGHL TLVGVWSHLA FADEPHHPSV REQARVFDDA
210 220 230 240 250
ITIVQAAGAH LEVRHIANSA ATLTAPELAY DLVRPGLAIY GLSPIPQVAS
260 270 280 290 300
AAELGLRPAM TVQADIATAK RLPAGHGVSY AHHYVTARDT HIAVIPLGYA
310 320 330 340 350
DGIPRHASGH NGELGAPVSI NGVTYAIAGR VCMDQIVIDV HDDSVRAGHT
360 370 380 390 400
ATLFGDPTLG VPSAQQWADA TGTISYEITT RIADRLPRMY LPTSDLHHAP
410
TVSQHSHTGG
Length:410
Mass (Da):42,844
Last modified:October 13, 2009 - v1
Checksum:i8F8F7BAA0CDC0FDF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001706 Genomic DNA. Translation: ACV08291.1.
RefSeqiWP_015770919.1. NC_013174.1.
YP_003160594.1. NC_013174.1.

Genome annotation databases

EnsemblBacteriaiACV08291; ACV08291; Jden_0627.
GeneIDi8379812.
KEGGijde:Jden_0627.
PATRICi22161302. VBIJonDen9837_0659.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001706 Genomic DNA. Translation: ACV08291.1 .
RefSeqi WP_015770919.1. NC_013174.1.
YP_003160594.1. NC_013174.1.

3D structure databases

ProteinModelPortali C7R176.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 471856.Jden_0627.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACV08291 ; ACV08291 ; Jden_0627 .
GeneIDi 8379812.
KEGGi jde:Jden_0627.
PATRICi 22161302. VBIJonDen9837_0659.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000031444.
KOi K01775.
OMAi LWQLEAI.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci JDEN471856:GH77-645-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 14870 / DSM 20603 / CIP 55134Imported.

Entry informationi

Entry nameiC7R176_JONDD
AccessioniPrimary (citable) accession number: C7R176
Entry historyi
Integrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: October 29, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3